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Protein

Apolipoprotein N-acyltransferase

Gene

lnt

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transfers the fatty acyl group on membrane lipoproteins.UniRule annotation

Pathwayi: lipoprotein biosynthesis (N-acyl transfer)

This protein is involved in the pathway lipoprotein biosynthesis (N-acyl transfer), which is part of Protein modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway lipoprotein biosynthesis (N-acyl transfer) and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei259Proton acceptorUniRule annotation1
Active sitei336UniRule annotation1
Active sitei372NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Hydrolase, Transferase

Enzyme and pathway databases

BioCyciRTYP257363:G1G0L-360-MONOMER
UniPathwayiUPA00666

Names & Taxonomyi

Protein namesi
Recommended name:
Apolipoprotein N-acyltransferaseUniRule annotation (EC:2.3.1.-UniRule annotation)
Short name:
ALP N-acyltransferaseUniRule annotation
Gene namesi
Name:lntUniRule annotation
Ordered Locus Names:RT0354
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000000604 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalUniRule annotationAdd BLAST21
Transmembranei50 – 70HelicalUniRule annotationAdd BLAST21
Transmembranei77 – 97HelicalUniRule annotationAdd BLAST21
Transmembranei114 – 134HelicalUniRule annotationAdd BLAST21
Transmembranei148 – 168HelicalUniRule annotationAdd BLAST21
Transmembranei183 – 203HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002780001 – 496Apolipoprotein N-acyltransferaseAdd BLAST496

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0354

Structurei

3D structure databases

ProteinModelPortaliQ68X09
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini220 – 464CN hydrolasePROSITE-ProRule annotationAdd BLAST245

Sequence similaritiesi

Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CE8 Bacteria
COG0815 LUCA
HOGENOMiHOG000010749
KOiK03820
OMAiPIGEFVP
OrthoDBiPOG091H05IH

Family and domain databases

CDDicd07571 ALP_N-acyl_transferase, 1 hit
Gene3Di3.60.110.10, 1 hit
HAMAPiMF_01148 Lnt, 1 hit
InterProiView protein in InterPro
IPR004563 Apolipo_AcylTrfase
IPR003010 C-N_Hydrolase
IPR036526 C-N_Hydrolase_sf
PfamiView protein in Pfam
PF00795 CN_hydrolase, 1 hit
SUPFAMiSSF56317 SSF56317, 1 hit
TIGRFAMsiTIGR00546 lnt, 1 hit
PROSITEiView protein in PROSITE
PS50263 CN_HYDROLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q68X09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKTKIICFL LGILSGLVFA PTFFIPALFT FSYLCYIVQK SQNWQAAAKF
60 70 80 90 100
GYLFGFGHFL SGMYWISIGV SVYIADFWWA IPFALFGLPI ILAFFISTNC
110 120 130 140 150
TLSFFAKNNK YYQLIFCLLW VLFEWIRSWI CTGLPWNLIG YAFSFSEILI
160 170 180 190 200
QPLSITGIYG LSFIVIYIAT SAYPVFSKNF TKLKILLASS MLILTVMVIY
210 220 230 240 250
GAMRVSTNPT HFTDIKVRLV QPSIPQTAKW DEEEFWHNLM LHINLSEKLE
260 270 280 290 300
PTDLIIWSEA ALVVPDDIPQ VKLELLNMLN STNAILITGG ISDNKKHGDK
310 320 330 340 350
FELYSAMYAL DKNNHKLFEY HKSHLVPFGE YMPLKKILPF KKLTHGLIDY
360 370 380 390 400
KEGNGGLVYI KKYHLKIKPL ICYESIFPNF VQTNNEIADV IINITNDSWY
410 420 430 440 450
GKSSGPYQHF HISRSRAVEN GLPMIRVANN GISAIVDPVG RIVKKLNLNE
460 470 480 490
INYIQGLIPQ KLTTPTIFSQ FGNFAMLLPI VFILLIHYLL SLIFDD
Length:496
Mass (Da):56,753
Last modified:October 11, 2004 - v1
Checksum:i1B86933596436171
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA Translation: AAU03833.1
RefSeqiWP_011190817.1, NC_006142.1

Genome annotation databases

EnsemblBacteriaiAAU03833; AAU03833; RT0354
KEGGirty:RT0354

Similar proteinsi

Entry informationi

Entry nameiLNT_RICTY
AccessioniPrimary (citable) accession number: Q68X09
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: October 11, 2004
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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