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Q68X09 (LNT_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Apolipoprotein N-acyltransferase

Short name=ALP N-acyltransferase
EC=2.3.1.-
Gene names
Name:lnt
Ordered Locus Names:RT0354
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers the fatty acyl group on membrane lipoproteins By similarity. HAMAP-Rule MF_01148

Pathway

Protein modification; lipoprotein biosynthesis (N-acyl transfer). HAMAP-Rule MF_01148

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01148.

Sequence similarities

Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.

Contains 1 CN hydrolase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 496496Apolipoprotein N-acyltransferase HAMAP-Rule MF_01148
PRO_0000278000

Regions

Transmembrane6 – 2621Helical; Potential
Transmembrane50 – 7021Helical; Potential
Transmembrane77 – 9721Helical; Potential
Transmembrane114 – 13421Helical; Potential
Transmembrane148 – 16821Helical; Potential
Transmembrane183 – 20321Helical; Potential
Domain215 – 496282CN hydrolase

Sites

Active site2591Proton acceptor Potential
Active site3361 Potential
Active site3721Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q68X09 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 1B86933596436171

FASTA49656,753
        10         20         30         40         50         60 
MYKTKIICFL LGILSGLVFA PTFFIPALFT FSYLCYIVQK SQNWQAAAKF GYLFGFGHFL 

        70         80         90        100        110        120 
SGMYWISIGV SVYIADFWWA IPFALFGLPI ILAFFISTNC TLSFFAKNNK YYQLIFCLLW 

       130        140        150        160        170        180 
VLFEWIRSWI CTGLPWNLIG YAFSFSEILI QPLSITGIYG LSFIVIYIAT SAYPVFSKNF 

       190        200        210        220        230        240 
TKLKILLASS MLILTVMVIY GAMRVSTNPT HFTDIKVRLV QPSIPQTAKW DEEEFWHNLM 

       250        260        270        280        290        300 
LHINLSEKLE PTDLIIWSEA ALVVPDDIPQ VKLELLNMLN STNAILITGG ISDNKKHGDK 

       310        320        330        340        350        360 
FELYSAMYAL DKNNHKLFEY HKSHLVPFGE YMPLKKILPF KKLTHGLIDY KEGNGGLVYI 

       370        380        390        400        410        420 
KKYHLKIKPL ICYESIFPNF VQTNNEIADV IINITNDSWY GKSSGPYQHF HISRSRAVEN 

       430        440        450        460        470        480 
GLPMIRVANN GISAIVDPVG RIVKKLNLNE INYIQGLIPQ KLTTPTIFSQ FGNFAMLLPI 

       490 
VFILLIHYLL SLIFDD 

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017197 Genomic DNA. Translation: AAU03833.1.
RefSeqYP_067315.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68X09.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257363.RT0354.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU03833; AAU03833; RT0354.
GeneID2958633.
KEGGrty:RT0354.
PATRIC17909912. VBIRicTyp34752_0370.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0815.
HOGENOMHOG000010749.
KOK03820.
OMAPIGEFVP.
OrthoDBEOG6VTJXM.
ProtClustDBPRK00302.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-371-MONOMER.
UniPathwayUPA00666.

Family and domain databases

Gene3D3.60.110.10. 1 hit.
HAMAPMF_01148. Lnt.
InterProIPR004563. Apolipo_AcylTrfase.
IPR003010. C-N_Hydrolase.
[Graphical view]
PfamPF00795. CN_hydrolase. 1 hit.
[Graphical view]
SUPFAMSSF56317. SSF56317. 1 hit.
TIGRFAMsTIGR00546. lnt. 1 hit.
PROSITEPS50263. CN_HYDROLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLNT_RICTY
AccessionPrimary (citable) accession number: Q68X09
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: October 11, 2004
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways