Q68WY2 (Y383_RICTY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative peptidyl-prolyl cis-trans isomerase RT0383
Short name=PPIase RT0383
EC=5.2.1.8

Alternative name(s):
Rotamase RT0383

Gene names

Ordered Locus Names:

RT0383

Organism

Rickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]

Taxonomic identifier

257363 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › Rickettsia typhi

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	Peptidylproline (omega=180) = peptidylproline (omega=0).
Sequence similarities	Contains 1 PPIase FKBP-type domain.

Ontologies

Keywords
Molecular function	Isomerase Rotamase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW protein peptidyl-prolyl isomerization Inferred from electronic annotation. Source: GOC
Molecular_function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 333	333	Putative peptidyl-prolyl cis-trans isomerase RT0383		PRO_0000279683
Regions
	Domain	129 – 227	99	PPIase FKBP-type

Sequences

	Sequence		Length	Mass (Da)
	Q68WY2 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: DAECDF4FFFBE1BC8	FASTA	333	37,058
	10 20 30 40 50 60 MQKFLSLIIV ILILYNIVKL KIYPEDNNNS TTIEQITSNN SSTNAHQASI NNEPTISLNG 70 80 90 100 110 120 NLFERTVSKI VINALKTEEG KVFFENILQP LNGPINPNDY TIEVHKDLVK TLFKINTFGS 130 140 150 160 170 180 GNIGPASCGH VVTVFYQISD MNNNLISEDT KTFTLGSAPV MLGLDNVIIG MMVGESREAI 190 200 210 220 230 240 IPAKYTVNNS NNTIFDDAYN YKVTVILKSI LPQNFVKSNK VKIYDDEIAY RVPLLCGEKV 250 260 270 280 290 300 SFNAKITRLS NGKILFDSKS TGQPIDMKIG DITYPLIFSY ALQGKVQVGT RSVIAESKTF 310 320 330 KALGSNLNKV IPHESLPIHE YLLLELNDFK QIK

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017197 Genomic DNA. Translation: AAU03860.1.
RefSeq	YP_067342.1. NC_006142.1.
3D structure databases
ProteinModelPortal	Q68WY2.
ModBase	Search...
Protein-protein interaction databases
STRING	257363.RT0383.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAU03860; AAU03860; RT0383.
GeneID	2958988.
KEGG	rty:RT0383.
PATRIC	17909982. VBIRicTyp34752_0403.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG10500.
HOGENOM	HOG000272836.
OMA	LLCGEKV.
ProtClustDB	CLSK870898.
Enzyme and pathway databases
BioCyc	RTYP257363:GJEQ-403-MONOMER.
Family and domain databases
InterPro	IPR001179. PPIase_FKBP_dom. [Graphical view]
Pfam	PF00254. FKBP_C. 1 hit. [Graphical view]
PROSITE	PS50059. FKBP_PPIASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y383_RICTY

Accession

Primary (citable) accession number: Q68WY2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 6, 2007
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program