Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q68WV5

- CDSA_RICTY

UniProt

Q68WV5 - CDSA_RICTY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-432-MONOMER.
UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:RT0410
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei31 – 5121HelicalSequence AnalysisAdd
BLAST
Transmembranei65 – 8521HelicalSequence AnalysisAdd
BLAST
Transmembranei93 – 11321HelicalSequence AnalysisAdd
BLAST
Transmembranei131 – 15121HelicalSequence AnalysisAdd
BLAST
Transmembranei165 – 18521HelicalSequence AnalysisAdd
BLAST
Transmembranei206 – 22621HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228Phosphatidate cytidylyltransferasePRO_0000281059Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0410.

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
HOGENOMiHOG000006169.
KOiK00981.
OMAiKTWSGLI.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68WV5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MITQKEKEHL AKDKQNIYLR IISGIVLVSL FVVAILWFKT LFYILMILVG
60 70 80 90 100
LGMLSEWCNM TSSSIHYLLI GFIIIPIPIS LLIFLSTQES NRLVIMLYFC
110 120 130 140 150
IIWSVDTFAM IGGKTFKGTK LAPKISPKKT WTGLIIGTIS AGLIAVLVSL
160 170 180 190 200
IPYYHIENYY FSNKIYLFII SCILALIAQS SDLFISYFKR KFNIKDSGHI
210 220
IPGHGGVLDR FDSIILTAPV FFGINIYL
Length:228
Mass (Da):25,817
Last modified:October 11, 2004 - v1
Checksum:i44225A1426C3E856
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03887.1.
RefSeqiYP_067369.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU03887; AAU03887; RT0410.
GeneIDi2958598.
KEGGirty:RT0410.
PATRICi17910054. VBIRicTyp34752_0439.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU03887.1 .
RefSeqi YP_067369.1. NC_006142.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0410.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU03887 ; AAU03887 ; RT0410 .
GeneIDi 2958598.
KEGGi rty:RT0410.
PATRICi 17910054. VBIRicTyp34752_0439.

Phylogenomic databases

eggNOGi COG0575.
HOGENOMi HOG000006169.
KOi K00981.
OMAi KTWSGLI.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .
BioCyci RTYP257363:GJEQ-432-MONOMER.

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiCDSA_RICTY
AccessioniPrimary (citable) accession number: Q68WV5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 11, 2004
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3