Q68WV5 (CDSA_RICTY) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 58.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphatidate cytidylyltransferase EC=2.7.7.41 Alternative name(s): CDP-DAG synthase CDP-DG synthase CDP-diacylglycerol synthase Short name=CDS CDP-diglyceride pyrophosphorylase CDP-diglyceride synthase CTP:phosphatidate cytidylyltransferase | ||||
| Gene names |
| ||||
| Organism | Rickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 257363 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group › ![]() |
Protein attributes
| Sequence length | 228 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | CTP + phosphatidate = diphosphate + CDP-diacylglycerol. |
| Pathway | |
| Subcellular location | Cell membrane; Multi-pass membrane protein By similarity. |
| Sequence similarities | Belongs to the CDS family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Lipid biosynthesis Lipid metabolism Phospholipid biosynthesis Phospholipid metabolism |
| Cellular component | Cell membrane Membrane |
| Domain | Transmembrane Transmembrane helix |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | CDP-diacylglycerol biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | phosphatidate cytidylyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 228 | 228 | Phosphatidate cytidylyltransferase | PRO_0000281059 | |||||
Regions | |||||||||
| Transmembrane | 31 – 51 | 21 | Helical; Potential | ||||||
| Transmembrane | 65 – 85 | 21 | Helical; Potential | ||||||
| Transmembrane | 93 – 113 | 21 | Helical; Potential | ||||||
| Transmembrane | 131 – 151 | 21 | Helical; Potential | ||||||
| Transmembrane | 165 – 185 | 21 | Helical; Potential | ||||||
| Transmembrane | 206 – 226 | 21 | Helical; Potential | ||||||
Sequences
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References
| [1] | "Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. Weinstock G.M.J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE017197 Genomic DNA. Translation: AAU03887.1. |
| RefSeq | YP_067369.1. NC_006142.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 257363.RT0410. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AAU03887; AAU03887; RT0410. |
| GeneID | 2958598. |
| KEGG | rty:RT0410. |
| PATRIC | 17910054. VBIRicTyp34752_0439. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0575. |
| HOGENOM | HOG000006169. |
| KO | K00981. |
| OMA | VELFNIM. |
| ProtClustDB | CLSK870917. |
Enzyme and pathway databases | |
| BioCyc | RTYP257363:GJEQ-432-MONOMER. |
| UniPathway | UPA00557; UER00614. |
Family and domain databases | |
| InterPro | IPR000374. PC_trans. [Graphical view] |
| Pfam | PF01148. CTP_transf_1. 1 hit. [Graphical view] |
| PROSITE | PS01315. CDS. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | CDSA_RICTY | ||||||||
| Accession | Primary (citable) accession number: Q68WV5 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Rickettsia typhi Rickettsia typhi (strain Wilmington): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
