ID   AMPG1_RICTY             Reviewed;         443 AA.
AC   Q68WQ5;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   RecName: Full=Putative transporter AmpG 1;
GN   Name=ampG1; OrderedLocusNames=RT0462;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE017197; AAU03937.1; -; Genomic_DNA.
DR   RefSeq; WP_011190920.1; NC_006142.1.
DR   AlphaFoldDB; Q68WQ5; -.
DR   KEGG; rty:RT0462; -.
DR   eggNOG; COG2807; Bacteria.
DR   HOGENOM; CLU_029352_1_2_5; -.
DR   OrthoDB; 9787815at2; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR004752; AmpG_permease/AT-1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   NCBIfam; TIGR00901; 2A0125; 1.
DR   PANTHER; PTHR12778:SF10; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR12778; SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..443
FT                   /note="Putative transporter AmpG 1"
FT                   /id="PRO_0000281102"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        394..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        416..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   443 AA;  50116 MW;  83770F2880DF074E CRC64;
     MLKNSHVCII IWLFGFISGF NIMITGNTLN YWFAKKDIAL QTIGILSFIT LPYSINFLLA
     PVFDTVQIKC LNKILGHRLS WICLTSTTLI SLTSILSFLD PGTDLVLLSF IAFIISFFSA
     TQDTILSALR TEIVPKELLG FTSGIYIFGY RVGMLLASSG AIYLSIYLTF NKIYQIFACV
     IFVYLILLIL VSRYTNSVDV IEENTSYFYV ARCYTMEEMH LKNEFFIKHY FNFFKNCISA
     YLLKIFSGSH VYRNDISLAY FIVLILIFLV LYRLPDNLIN VMINPFLLHL GYNAFEIASV
     CKFCGVIGAI IGGLIGGIIM KYKNMLYSIL LFGIIHALSH ILFILLEVNG KNSLILFITI
     GIESITGGMT MTAYIAFISS LCQGKFRATQ YSLLSSMMGI SRSIFPIISG YMVVNFGWQN
     FFLFTTIITI PSLLILLKIQ TKL
//