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Q68WQ3

- TLCC_RICTY

UniProt

Q68WQ3 - TLCC_RICTY

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Protein

ADP,ATP carrier protein 3

Gene
tlcC, tlc3, RT0464
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.

GO - Molecular functioni

  1. ATP:ADP antiporter activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-486-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
ADP,ATP carrier protein 3
Alternative name(s):
ADP/ATP translocase 3
Gene namesi
Name:tlcC
Synonyms:tlc3
Ordered Locus Names:RT0464
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321Helical; Reviewed predictionAdd
BLAST
Transmembranei59 – 7921Helical; Reviewed predictionAdd
BLAST
Transmembranei90 – 11021Helical; Reviewed predictionAdd
BLAST
Transmembranei146 – 16621Helical; Reviewed predictionAdd
BLAST
Transmembranei183 – 20321Helical; Reviewed predictionAdd
BLAST
Transmembranei227 – 24721Helical; Reviewed predictionAdd
BLAST
Transmembranei293 – 31321Helical; Reviewed predictionAdd
BLAST
Transmembranei326 – 34621Helical; Reviewed predictionAdd
BLAST
Transmembranei361 – 38121Helical; Reviewed predictionAdd
BLAST
Transmembranei383 – 40321Helical; Reviewed predictionAdd
BLAST
Transmembranei446 – 46621Helical; Reviewed predictionAdd
BLAST
Transmembranei470 – 49021Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 501501ADP,ATP carrier protein 3PRO_0000286474Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0464.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3202.
HOGENOMiHOG000238123.
OMAiHPNTIDY.
OrthoDBiEOG6BCSND.

Family and domain databases

InterProiIPR004667. ADP_ATP_car.
[Graphical view]
PfamiPF03219. TLC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00769. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q68WQ3-1 [UniParc]FASTAAdd to Basket

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MLPPKIFFEK FKEIIWPIER KELKLFIPMA LMMLCILFNF GALRSIKDSL    50
VVPSMGAEII SFLKLWLVLP SCVIFTVLYV KLSNKLNFEY IFYSIVGTFL 100
LFFLLFAYII YPNQDIYHPN DAMINNLIAS YPNLKWFIKI GSKWSYALMY 150
IFSELWSAVV INLMFWQFAN HIFDTAKAKR FYPVLGMIGN IGLIIAGSVL 200
VFFSSGQYII DSELLTDSFN SSSCNSIILQ PIISIIVTAG IIAMFLFRII 250
NRFILTNAIN VLDVKKAAAR TKTKLALIES IKLIIHSKYI GRIALLIICY 300
GLLINIVEGP WKAKIKELHP NTIDYVNFMG MFNIWMGISC VTFMIIGSNI 350
LRRLGWLISA LLTPIMLSIT GFIFFIFIIF IEEIGTCFGD FNLLYVAIIV 400
GAIQNILSKS SKYSLFDSTK EMAYIPLSLE LRTKGKAAVE VIGTKFGKSL 450
GAFIQSLIFI IIPTATFDSI IIYLLVIFIV MMNLWIWNII KLNKEYIKLC 500
K 501
Length:501
Mass (Da):57,193
Last modified:October 11, 2004 - v1
Checksum:i5145AEB78D2B2F23
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU03939.1.
RefSeqiYP_067421.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU03939; AAU03939; RT0464.
GeneIDi2958702.
KEGGirty:RT0464.
PATRICi17910170. VBIRicTyp34752_0495.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU03939.1 .
RefSeqi YP_067421.1. NC_006142.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0464.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU03939 ; AAU03939 ; RT0464 .
GeneIDi 2958702.
KEGGi rty:RT0464.
PATRICi 17910170. VBIRicTyp34752_0495.

Phylogenomic databases

eggNOGi COG3202.
HOGENOMi HOG000238123.
OMAi HPNTIDY.
OrthoDBi EOG6BCSND.

Enzyme and pathway databases

BioCyci RTYP257363:GJEQ-486-MONOMER.

Family and domain databases

InterProi IPR004667. ADP_ATP_car.
[Graphical view ]
Pfami PF03219. TLC. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00769. AAA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiTLCC_RICTY
AccessioniPrimary (citable) accession number: Q68WQ3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi