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Q68WQ3

- TLCC_RICTY

UniProt

Q68WQ3 - TLCC_RICTY

Protein

ADP,ATP carrier protein 3

Gene

tlcC

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism By similarity.By similarity

    GO - Molecular functioni

    1. ATP:ADP antiporter activity Source: InterPro
    2. ATP binding Source: UniProtKB-KW

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-486-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ADP,ATP carrier protein 3
    Alternative name(s):
    ADP/ATP translocase 3
    Gene namesi
    Name:tlcC
    Synonyms:tlc3
    Ordered Locus Names:RT0464
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 501501ADP,ATP carrier protein 3PRO_0000286474Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi257363.RT0464.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei23 – 4321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei59 – 7921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei90 – 11021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei146 – 16621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei183 – 20321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei227 – 24721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei293 – 31321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei326 – 34621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei361 – 38121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei383 – 40321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei446 – 46621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei470 – 49021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ADP/ATP translocase tlc family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG3202.
    HOGENOMiHOG000238123.
    OMAiHPNTIDY.
    OrthoDBiEOG6BCSND.

    Family and domain databases

    InterProiIPR004667. ADP_ATP_car.
    [Graphical view]
    PfamiPF03219. TLC. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00769. AAA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q68WQ3-1 [UniParc]FASTAAdd to Basket

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    MLPPKIFFEK FKEIIWPIER KELKLFIPMA LMMLCILFNF GALRSIKDSL    50
    VVPSMGAEII SFLKLWLVLP SCVIFTVLYV KLSNKLNFEY IFYSIVGTFL 100
    LFFLLFAYII YPNQDIYHPN DAMINNLIAS YPNLKWFIKI GSKWSYALMY 150
    IFSELWSAVV INLMFWQFAN HIFDTAKAKR FYPVLGMIGN IGLIIAGSVL 200
    VFFSSGQYII DSELLTDSFN SSSCNSIILQ PIISIIVTAG IIAMFLFRII 250
    NRFILTNAIN VLDVKKAAAR TKTKLALIES IKLIIHSKYI GRIALLIICY 300
    GLLINIVEGP WKAKIKELHP NTIDYVNFMG MFNIWMGISC VTFMIIGSNI 350
    LRRLGWLISA LLTPIMLSIT GFIFFIFIIF IEEIGTCFGD FNLLYVAIIV 400
    GAIQNILSKS SKYSLFDSTK EMAYIPLSLE LRTKGKAAVE VIGTKFGKSL 450
    GAFIQSLIFI IIPTATFDSI IIYLLVIFIV MMNLWIWNII KLNKEYIKLC 500
    K 501
    Length:501
    Mass (Da):57,193
    Last modified:October 11, 2004 - v1
    Checksum:i5145AEB78D2B2F23
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU03939.1.
    RefSeqiYP_067421.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU03939; AAU03939; RT0464.
    GeneIDi2958702.
    KEGGirty:RT0464.
    PATRICi17910170. VBIRicTyp34752_0495.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU03939.1 .
    RefSeqi YP_067421.1. NC_006142.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0464.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU03939 ; AAU03939 ; RT0464 .
    GeneIDi 2958702.
    KEGGi rty:RT0464.
    PATRICi 17910170. VBIRicTyp34752_0495.

    Phylogenomic databases

    eggNOGi COG3202.
    HOGENOMi HOG000238123.
    OMAi HPNTIDY.
    OrthoDBi EOG6BCSND.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-486-MONOMER.

    Family and domain databases

    InterProi IPR004667. ADP_ATP_car.
    [Graphical view ]
    Pfami PF03219. TLC. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00769. AAA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiTLCC_RICTY
    AccessioniPrimary (citable) accession number: Q68WQ3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3