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Q68WM3 (Q68WM3_RICTY) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase subunit beta PIRNR PIRNR000355
EC=1.17.4.1 PIRNR PIRNR000355
Gene names
Name:nrdB EMBL AAU03969.1
Ordered Locus Names:RT0497
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP] EMBL AAU03969.1
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group ›

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. PIRNR PIRNR000355

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. PIRNR PIRNR000355

Cofactor

Binds 2 iron ions per subunit By similarity. PIRNR PIRNR000355

Pathway

Genetic information processing; DNA replication. PIRNR PIRNR000355

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family. PIRNR PIRNR000355

Sequences

Sequence LengthMass (Da)Tools
Q68WM3 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 7240884EC9767498

FASTA32438,015
        10         20         30         40         50         60 
MSLLDASPIY KPFSYPWAYE AWHTQQKIHW LPEEVPLAYD VKDWKYNLTP GEKHLLTQIF 

        70         80         90        100        110        120 
RFFTQADIEV NNCYMKHYSR VFKPTEVLMM LSAFSNMETV HIAAYSHLLD TVGMPEVEYS 

       130        140        150        160        170        180 
AFLKYKEMKD KYDYMQQFGV DNKEDIATTL AVFGAFTEGL QLFASFAIML NFPRFNKMKG 

       190        200        210        220        230        240 
MGQIIAWSVR DETLHTNSII TLFKTFVREN PEVWTETLRK RIYEACTTIV HFEDAFIELA 

       250        260        270        280        290        300 
FEVGGIEGLT AYEVRQYIRY IADRRLMQLG LKDVYLVNHN PLPWLDEMLN GVEHTNFFEN 

       310        320 
RATEYSKAAT TGSWEEVFAE MDNK

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References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017197 Genomic DNA. Translation: AAU03969.1.
RefSeqYP_067451.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68WM3.
ModBaseSearch...

Protein-protein interaction databases

STRING257363.RT0497.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU03969; AAU03969; RT0497.
GeneID2958575.
KEGGrty:RT0497.
PATRIC17910238. VBIRicTyp34752_0527.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000064511.
KOK00526.
OMAICNRRCQ.
ProtClustDBPRK09614.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-522-MONOMER.
UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFPIRSF000355. NrdB. 1 hit.
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ68WM3_RICTY
AccessionPrimary (citable) accession number: Q68WM3
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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