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Q68WK0

- SODF_RICTY

UniProt

Q68WK0 - SODF_RICTY

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Protein
Superoxide dismutase [Mn/Fe]
Gene
sodB, RT0523
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Binds 1 manganese or iron ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi38 – 381Manganese or iron By similarity
Metal bindingi90 – 901Manganese or iron By similarity
Metal bindingi172 – 1721Manganese or iron By similarity
Metal bindingi176 – 1761Manganese or iron By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    Iron, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-549-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Superoxide dismutase [Mn/Fe] (EC:1.15.1.1)
    Gene namesi
    Name:sodB
    Ordered Locus Names:RT0523
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 209209Superoxide dismutase [Mn/Fe]
    PRO_0000286503Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi257363.RT0523.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68WK0.
    SMRiQ68WK0. Positions 14-207.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0605.
    HOGENOMiHOG000013584.
    KOiK04564.
    OMAiDSLINWD.
    OrthoDBiEOG63NMNT.

    Family and domain databases

    InterProiIPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view]
    PANTHERiPTHR11404. PTHR11404. 1 hit.
    PfamiPF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000349. SODismutase. 1 hit.
    PRINTSiPR01703. MNSODISMTASE.
    SUPFAMiSSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEiPS00088. SOD_MN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q68WK0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTYCRKANQT SYPFILPDLP YAKESFKPHF TCETFDYHHG KHHNSYVQNL    50
    NNLLKDREEL QKKDLEGIIK WSSKNSEVTV FNNASQIWNH TFFWYSIKPH 100
    GGGKPSGKVF EQISQDFGSF EQFCEQFKQE ALGQFGSGWV WVVYNNNKLQ 150
    IIKTSNADTP IVNLMKPILV CDVWEHAYYI DYRNKRSDYI DIFISHMINW 200
    KFVEDNLIQ 209
    Length:209
    Mass (Da):24,737
    Last modified:October 11, 2004 - v1
    Checksum:i1EB8AB024554EB8A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU03992.1.
    RefSeqiYP_067474.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU03992; AAU03992; RT0523.
    GeneIDi2958824.
    KEGGirty:RT0523.
    PATRICi17910286. VBIRicTyp34752_0548.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU03992.1 .
    RefSeqi YP_067474.1. NC_006142.1.

    3D structure databases

    ProteinModelPortali Q68WK0.
    SMRi Q68WK0. Positions 14-207.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0523.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU03992 ; AAU03992 ; RT0523 .
    GeneIDi 2958824.
    KEGGi rty:RT0523.
    PATRICi 17910286. VBIRicTyp34752_0548.

    Phylogenomic databases

    eggNOGi COG0605.
    HOGENOMi HOG000013584.
    KOi K04564.
    OMAi DSLINWD.
    OrthoDBi EOG63NMNT.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-549-MONOMER.

    Family and domain databases

    InterProi IPR001189. Mn/Fe_SOD.
    IPR019833. Mn/Fe_SOD_BS.
    IPR019832. Mn/Fe_SOD_C.
    IPR019831. Mn/Fe_SOD_N.
    [Graphical view ]
    PANTHERi PTHR11404. PTHR11404. 1 hit.
    Pfami PF02777. Sod_Fe_C. 1 hit.
    PF00081. Sod_Fe_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000349. SODismutase. 1 hit.
    PRINTSi PR01703. MNSODISMTASE.
    SUPFAMi SSF46609. SSF46609. 1 hit.
    SSF54719. SSF54719. 1 hit.
    PROSITEi PS00088. SOD_MN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiSODF_RICTY
    AccessioniPrimary (citable) accession number: Q68WK0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 15, 2007
    Last sequence update: October 11, 2004
    Last modified: July 9, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3

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