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Q68WK0 (SODF_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Superoxide dismutase [Mn/Fe]
EC=1.15.1.1
Gene names
Name:sodB
Ordered Locus Names:RT0523
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group ›

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 manganese or iron ion per subunit By similarity.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
   LigandIron
Manganese
Metal-binding
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processsuperoxide metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 209209Superoxide dismutase [Mn/Fe]
PRO_0000286503

Sites

Metal binding381Manganese or iron By similarity
Metal binding901Manganese or iron By similarity
Metal binding1721Manganese or iron By similarity
Metal binding1761Manganese or iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q68WK0 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 1EB8AB024554EB8A

FASTA20924,737
        10         20         30         40         50         60 
MTYCRKANQT SYPFILPDLP YAKESFKPHF TCETFDYHHG KHHNSYVQNL NNLLKDREEL 

        70         80         90        100        110        120 
QKKDLEGIIK WSSKNSEVTV FNNASQIWNH TFFWYSIKPH GGGKPSGKVF EQISQDFGSF 

       130        140        150        160        170        180 
EQFCEQFKQE ALGQFGSGWV WVVYNNNKLQ IIKTSNADTP IVNLMKPILV CDVWEHAYYI 

       190        200 
DYRNKRSDYI DIFISHMINW KFVEDNLIQ

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References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017197 Genomic DNA. Translation: AAU03992.1.
RefSeqYP_067474.1. NC_006142.1.

3D structure databases

HSSPHSSP built from PDB template 2A03 based on UniProtKB Q4YW77.
ProteinModelPortalQ68WK0.
SMRQ68WK0. Positions 14-207.
ModBaseSearch...

Protein-protein interaction databases

STRING257363.RT0523.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU03992; AAU03992; RT0523.
GeneID2958824.
KEGGrty:RT0523.
PATRIC17910286. VBIRicTyp34752_0548.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0605.
HOGENOMHOG000013584.
KOK04564.
OMANCMAPNG.
ProtClustDBCLSK870979.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-549-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SODismutase. 1 hit.
SSF54719. SODismutase. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODF_RICTY
AccessionPrimary (citable) accession number: Q68WK0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: October 11, 2004
Last modified: May 1, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names

SIMILARITY comments

Index of protein domains and families

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