Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q68WJ7

- NUON_RICTY

UniProt

Q68WJ7 - NUON_RICTY

Protein

NADH-quinone oxidoreductase subunit N

Gene

nuoN

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.UniRule annotation

    Catalytic activityi

    NADH + quinone = NAD+ + quinol.UniRule annotation

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
    2. quinone binding Source: UniProtKB-KW

    GO - Biological processi

    1. ATP synthesis coupled electron transport Source: InterPro
    2. transport Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-552-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH-quinone oxidoreductase subunit NUniRule annotation (EC:1.6.99.5UniRule annotation)
    Alternative name(s):
    NADH dehydrogenase I subunit NUniRule annotation
    NDH-1 subunit NUniRule annotation
    Gene namesi
    Name:nuoNUniRule annotation
    Ordered Locus Names:RT0526
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 458458NADH-quinone oxidoreductase subunit NPRO_0000272333Add
    BLAST

    Keywords - PTMi

    Quinone

    Interactioni

    Subunit structurei

    NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi257363.RT0526.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei2 – 2221HelicalUniRule annotationAdd
    BLAST
    Transmembranei30 – 5021HelicalUniRule annotationAdd
    BLAST
    Transmembranei62 – 8221HelicalUniRule annotationAdd
    BLAST
    Transmembranei93 – 11321HelicalUniRule annotationAdd
    BLAST
    Transmembranei118 – 13821HelicalUniRule annotationAdd
    BLAST
    Transmembranei153 – 17321HelicalUniRule annotationAdd
    BLAST
    Transmembranei196 – 21621HelicalUniRule annotationAdd
    BLAST
    Transmembranei235 – 25521HelicalUniRule annotationAdd
    BLAST
    Transmembranei261 – 28121HelicalUniRule annotationAdd
    BLAST
    Transmembranei290 – 31021HelicalUniRule annotationAdd
    BLAST
    Transmembranei319 – 33921HelicalUniRule annotationAdd
    BLAST
    Transmembranei361 – 38121HelicalUniRule annotationAdd
    BLAST
    Transmembranei397 – 41721HelicalUniRule annotationAdd
    BLAST
    Transmembranei438 – 45821HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I subunit 2 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1007.
    HOGENOMiHOG000010703.
    KOiK00343.
    OMAiIDKLSWI.
    OrthoDBiEOG64JFNZ.

    Family and domain databases

    HAMAPiMF_00445. NDH1_NuoN_1.
    InterProiIPR010096. NADH-Q_OxRdtase_suN/2.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    [Graphical view]
    PfamiPF00361. Oxidored_q1. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01770. NDH_I_N. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q68WJ7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLLILPEITL TLIALLGQCF ALMIPNKNKI IYNIVILLCI ISIFLTFKYS    50
    SYEGIWHSFA TGINIGISKS IVLLFTIVSL IIYRDYSNLI GEAIKFEFIT 100
    LILLSIVGIF VAISSRNFLL LFCGMELTAL TSYALAGFKL DDIQSSEGAL 150
    KYFILGSLVT CLSLFGISFI YGFGGSIQFE DILHQLNNNS EIKPGLIIGI 200
    VLFLSSIFFK LASSPLHFWI PDVYEGSPIS SITYFTSAAK IGMVIVLFNI 250
    SKLIIGNYYP INYNLIKIIA ILSMLFGAFG AIQQTSLKRL MAYSTILNIG 300
    YVLIGVILPN QEGYKAALLY ILIYAVVSIG FFTCLIMLFG KDVDKASFKT 350
    IQGIAETHKT IAALISIVMF SMIGIPPLTG FFGKYYLFYQ AINKQEFTLA 400
    YCGIFTSVVA AFYYLKVVKA MYFSKKNSII KLPIQYGLLL INYLVLVFLL 450
    FGSFIILF 458
    Length:458
    Mass (Da):51,036
    Last modified:October 11, 2004 - v1
    Checksum:i38151D913207A51A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU03995.1.
    RefSeqiYP_067477.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU03995; AAU03995; RT0526.
    GeneIDi2958745.
    KEGGirty:RT0526.
    PATRICi17910290. VBIRicTyp34752_0550.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU03995.1 .
    RefSeqi YP_067477.1. NC_006142.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0526.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU03995 ; AAU03995 ; RT0526 .
    GeneIDi 2958745.
    KEGGi rty:RT0526.
    PATRICi 17910290. VBIRicTyp34752_0550.

    Phylogenomic databases

    eggNOGi COG1007.
    HOGENOMi HOG000010703.
    KOi K00343.
    OMAi IDKLSWI.
    OrthoDBi EOG64JFNZ.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-552-MONOMER.

    Family and domain databases

    HAMAPi MF_00445. NDH1_NuoN_1.
    InterProi IPR010096. NADH-Q_OxRdtase_suN/2.
    IPR001750. NADH_UbQ/plastoQ_OxRdtase.
    [Graphical view ]
    Pfami PF00361. Oxidored_q1. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01770. NDH_I_N. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiNUON_RICTY
    AccessioniPrimary (citable) accession number: Q68WJ7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 23, 2007
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3