Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q68WD8

- DNAA_RICTY

UniProt

Q68WD8 - DNAA_RICTY

Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi168 – 1758ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA replication origin binding Source: UniProtKB-HAMAP
    3. nucleoside-triphosphatase activity Source: InterPro

    GO - Biological processi

    1. DNA replication initiation Source: UniProtKB-HAMAP
    2. regulation of DNA replication Source: UniProtKB-HAMAP

    Keywords - Biological processi

    DNA replication

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-619-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chromosomal replication initiator protein DnaAUniRule annotation
    Gene namesi
    Name:dnaAUniRule annotation
    Ordered Locus Names:RT0589
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 463463Chromosomal replication initiator protein DnaAPRO_0000114248Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi257363.RT0589.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68WD8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the DnaA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0593.
    HOGENOMiHOG000235660.
    KOiK02313.
    OMAiLPHEPRQ.
    OrthoDBiEOG689HR1.

    Family and domain databases

    Gene3Di1.10.1750.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00377. DnaA_bact.
    InterProiIPR003593. AAA+_ATPase.
    IPR001957. Chromosome_initiator_DnaA.
    IPR020591. Chromosome_initiator_DnaA-like.
    IPR018312. Chromosome_initiator_DnaA_CS.
    IPR013159. DnaA_C.
    IPR013317. DnaA_Hda.
    IPR024633. DnaA_N_dom.
    IPR027417. P-loop_NTPase.
    IPR010921. Trp_repressor/repl_initiator.
    [Graphical view]
    PfamiPF00308. Bac_DnaA. 1 hit.
    PF08299. Bac_DnaA_C. 1 hit.
    PF11638. DnaA_N. 1 hit.
    [Graphical view]
    PRINTSiPR00051. DNAA.
    SMARTiSM00382. AAA. 1 hit.
    SM00760. Bac_DnaA_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48295. SSF48295. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00362. DnaA. 1 hit.
    PROSITEiPS01008. DNAA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q68WD8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTNQIPLTD QGDNYVNVWS YVAQDLYNHY GETLYNSWFS KVNFIESSLN    50
    TVILCAPTNF IRDWIKSKYA MVILQLFQHY NNAIKSIEII TKEVPGTTQT 100
    VIELPTKTFS NISNSALNSE NTISTLDLRF TFDNFVVGAP NELAYAAARA 150
    VAESSGAVFE SNPLFLYGGV GLGKTHLMHA IGWYIKQNNP SRKVIYMSAE 200
    KFMYQFVKAL RNKEVILFKE KFRSVDVLMI DDIQFICGKD STQEEFFHTF 250
    NTLIDNNRQM VISCDRSPSD LDNIEDRIKS RLGWGLVADV HSTTYELRLG 300
    ILESKIEQMN VKIPKDVINF LASKIVSNVR ELEGALNKVI AHSNFTLKAI 350
    TLENTQNILR DLLRSNERII TVEDIQKKVA NRYNIKLSDM YSSRRLREVA 400
    RPRQIAMYLS KILTPKSLAD IGKKFGKKDH TTVMHAIKKV EELLENDIEL 450
    REEINLLMKI LQN 463
    Length:463
    Mass (Da):53,050
    Last modified:October 11, 2004 - v1
    Checksum:i4ECCE1C474171366
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04054.1.
    RefSeqiYP_067536.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU04054; AAU04054; RT0589.
    GeneIDi2959355.
    KEGGirty:RT0589.
    PATRICi17910414. VBIRicTyp34752_0608.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04054.1 .
    RefSeqi YP_067536.1. NC_006142.1.

    3D structure databases

    ProteinModelPortali Q68WD8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0589.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU04054 ; AAU04054 ; RT0589 .
    GeneIDi 2959355.
    KEGGi rty:RT0589.
    PATRICi 17910414. VBIRicTyp34752_0608.

    Phylogenomic databases

    eggNOGi COG0593.
    HOGENOMi HOG000235660.
    KOi K02313.
    OMAi LPHEPRQ.
    OrthoDBi EOG689HR1.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-619-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1750.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00377. DnaA_bact.
    InterProi IPR003593. AAA+_ATPase.
    IPR001957. Chromosome_initiator_DnaA.
    IPR020591. Chromosome_initiator_DnaA-like.
    IPR018312. Chromosome_initiator_DnaA_CS.
    IPR013159. DnaA_C.
    IPR013317. DnaA_Hda.
    IPR024633. DnaA_N_dom.
    IPR027417. P-loop_NTPase.
    IPR010921. Trp_repressor/repl_initiator.
    [Graphical view ]
    Pfami PF00308. Bac_DnaA. 1 hit.
    PF08299. Bac_DnaA_C. 1 hit.
    PF11638. DnaA_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00051. DNAA.
    SMARTi SM00382. AAA. 1 hit.
    SM00760. Bac_DnaA_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48295. SSF48295. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00362. DnaA. 1 hit.
    PROSITEi PS01008. DNAA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiDNAA_RICTY
    AccessioniPrimary (citable) accession number: Q68WD8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 15, 2005
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3