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Q68WD4

- PTH_RICTY

UniProt

Q68WD4 - PTH_RICTY

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Protein

Peptidyl-tRNA hydrolase

Gene
pth, RT0593
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA hydrolase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-623-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolase (EC:3.1.1.29)
Short name:
PTH
Gene namesi
Name:pth
Ordered Locus Names:RT0593
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 185185Peptidyl-tRNA hydrolaseUniRule annotationPRO_0000187806Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi257363.RT0593.

Structurei

3D structure databases

ProteinModelPortaliQ68WD4.

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.

Phylogenomic databases

eggNOGiCOG0193.
HOGENOMiHOG000004797.
KOiK01056.
OMAiSLDAHCG.
OrthoDBiEOG6C5RTR.

Family and domain databases

Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68WD4-1 [UniParc]FASTAAdd to Basket

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MILVIGLGNP GIVYQYTRHN IGFIAIERIA NKYHLSFSTK QKFNCKIAEA    50
IIDRQKICFI KPTTYMNLSG KSVILVKTYY NINYEKVFVI HDDIDLEIGR 100
IKFKTGGSNG GHNGLKSIDS IIGSHYNRIR IGIGRPQNNH DVADYVLSNF 150
SESEYKTVMQ SIDNVANNFG LILEHKLAEF KNKIV 185
Length:185
Mass (Da):21,000
Last modified:October 11, 2004 - v1
Checksum:iE883C0F496FCE7E9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU04058.1.
RefSeqiYP_067540.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU04058; AAU04058; RT0593.
GeneIDi2959396.
KEGGirty:RT0593.
PATRICi17910426. VBIRicTyp34752_0614.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU04058.1 .
RefSeqi YP_067540.1. NC_006142.1.

3D structure databases

ProteinModelPortali Q68WD4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0593.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU04058 ; AAU04058 ; RT0593 .
GeneIDi 2959396.
KEGGi rty:RT0593.
PATRICi 17910426. VBIRicTyp34752_0614.

Phylogenomic databases

eggNOGi COG0193.
HOGENOMi HOG000004797.
KOi K01056.
OMAi SLDAHCG.
OrthoDBi EOG6C5RTR.

Enzyme and pathway databases

BioCyci RTYP257363:GJEQ-623-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1470. 1 hit.
HAMAPi MF_00083. Pept_tRNA_hydro_bact.
InterProi IPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view ]
PANTHERi PTHR17224. PTHR17224. 1 hit.
Pfami PF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view ]
SUPFAMi SSF53178. SSF53178. 1 hit.
TIGRFAMsi TIGR00447. pth. 1 hit.
PROSITEi PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiPTH_RICTY
AccessioniPrimary (citable) accession number: Q68WD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi