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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciRTYP257363:G1G0L-599-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:RT0593
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
Proteomesi
  • UP000000604 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001878061 – 185Peptidyl-tRNA hydrolaseAdd BLAST185

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi257363.RT0593

Structurei

3D structure databases

ProteinModelPortaliQ68WD4
SMRiQ68WD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH
OrthoDBiPOG091H02CU

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.14701 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit
PS01196 PEPT_TRNA_HYDROL_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q68WD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILVIGLGNP GIVYQYTRHN IGFIAIERIA NKYHLSFSTK QKFNCKIAEA
60 70 80 90 100
IIDRQKICFI KPTTYMNLSG KSVILVKTYY NINYEKVFVI HDDIDLEIGR
110 120 130 140 150
IKFKTGGSNG GHNGLKSIDS IIGSHYNRIR IGIGRPQNNH DVADYVLSNF
160 170 180
SESEYKTVMQ SIDNVANNFG LILEHKLAEF KNKIV
Length:185
Mass (Da):21,000
Last modified:October 11, 2004 - v1
Checksum:iE883C0F496FCE7E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA Translation: AAU04058.1
RefSeqiWP_011191039.1, NC_006142.1

Genome annotation databases

EnsemblBacteriaiAAU04058; AAU04058; RT0593
KEGGirty:RT0593

Similar proteinsi

Entry informationi

Entry nameiPTH_RICTY
AccessioniPrimary (citable) accession number: Q68WD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: October 11, 2004
Last modified: February 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome