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Q68W83

- RL22_RICTY

UniProt

Q68W83 - RL22_RICTY

Protein

50S ribosomal protein L22

Gene

rplV

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity.UniRule annotation
    The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-677-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L22UniRule annotation
    Gene namesi
    Name:rplVUniRule annotation
    Ordered Locus Names:RT0646
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11911950S ribosomal protein L22PRO_0000243200Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi257363.RT0646.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68W83.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L22P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0091.
    HOGENOMiHOG000205046.
    KOiK02890.
    OMAiRILKPTC.
    OrthoDBiEOG6V4GKB.

    Family and domain databases

    Gene3Di3.90.470.10. 1 hit.
    HAMAPiMF_01331_B. Ribosomal_L22_B.
    InterProiIPR001063. Ribosomal_L22.
    IPR018260. Ribosomal_L22/L17_CS.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view]
    PANTHERiPTHR13501. PTHR13501. 1 hit.
    PfamiPF00237. Ribosomal_L22. 1 hit.
    [Graphical view]
    SUPFAMiSSF54843. SSF54843. 1 hit.
    TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
    PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q68W83-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIQENKNFAT AKAKSIRVSP RKLNLVASFI RNMKVSEALI QLTFSPKRIA    50
    KIVKDCLRSA VANAENNLGL DIDRLIITKA TVGKSVVMKR IMPRAKGRAT 100
    RINKFFSNLD ITVTEKEDN 119
    Length:119
    Mass (Da):13,345
    Last modified:October 11, 2004 - v1
    Checksum:iC82FF54CA899ECBA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04109.1.
    RefSeqiYP_067591.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU04109; AAU04109; RT0646.
    GeneIDi2958919.
    KEGGirty:RT0646.
    PATRICi17910534. VBIRicTyp34752_0666.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04109.1 .
    RefSeqi YP_067591.1. NC_006142.1.

    3D structure databases

    ProteinModelPortali Q68W83.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0646.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU04109 ; AAU04109 ; RT0646 .
    GeneIDi 2958919.
    KEGGi rty:RT0646.
    PATRICi 17910534. VBIRicTyp34752_0666.

    Phylogenomic databases

    eggNOGi COG0091.
    HOGENOMi HOG000205046.
    KOi K02890.
    OMAi RILKPTC.
    OrthoDBi EOG6V4GKB.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-677-MONOMER.

    Family and domain databases

    Gene3Di 3.90.470.10. 1 hit.
    HAMAPi MF_01331_B. Ribosomal_L22_B.
    InterProi IPR001063. Ribosomal_L22.
    IPR018260. Ribosomal_L22/L17_CS.
    IPR005727. Ribosomal_L22_bac/chlpt-type.
    [Graphical view ]
    PANTHERi PTHR13501. PTHR13501. 1 hit.
    Pfami PF00237. Ribosomal_L22. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54843. SSF54843. 1 hit.
    TIGRFAMsi TIGR01044. rplV_bact. 1 hit.
    PROSITEi PS00464. RIBOSOMAL_L22. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiRL22_RICTY
    AccessioniPrimary (citable) accession number: Q68W83
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 27, 2006
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Ribosomal proteins
      Ribosomal proteins families and list of entries
    2. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3