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Q68W83

- RL22_RICTY

UniProt

Q68W83 - RL22_RICTY

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Protein

50S ribosomal protein L22

Gene

rplV

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).UniRule annotation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-677-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L22UniRule annotation
Gene namesi
Name:rplVUniRule annotation
Ordered Locus Names:RT0646
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11911950S ribosomal protein L22PRO_0000243200Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi257363.RT0646.

Structurei

3D structure databases

ProteinModelPortaliQ68W83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L22P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0091.
HOGENOMiHOG000205046.
KOiK02890.
OMAiRILKPTC.
OrthoDBiEOG6V4GKB.

Family and domain databases

Gene3Di3.90.470.10. 1 hit.
HAMAPiMF_01331_B. Ribosomal_L22_B.
InterProiIPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68W83-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIQENKNFAT AKAKSIRVSP RKLNLVASFI RNMKVSEALI QLTFSPKRIA
60 70 80 90 100
KIVKDCLRSA VANAENNLGL DIDRLIITKA TVGKSVVMKR IMPRAKGRAT
110
RINKFFSNLD ITVTEKEDN
Length:119
Mass (Da):13,345
Last modified:October 11, 2004 - v1
Checksum:iC82FF54CA899ECBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU04109.1.
RefSeqiYP_067591.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU04109; AAU04109; RT0646.
GeneIDi2958919.
KEGGirty:RT0646.
PATRICi17910534. VBIRicTyp34752_0666.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU04109.1 .
RefSeqi YP_067591.1. NC_006142.1.

3D structure databases

ProteinModelPortali Q68W83.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0646.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU04109 ; AAU04109 ; RT0646 .
GeneIDi 2958919.
KEGGi rty:RT0646.
PATRICi 17910534. VBIRicTyp34752_0666.

Phylogenomic databases

eggNOGi COG0091.
HOGENOMi HOG000205046.
KOi K02890.
OMAi RILKPTC.
OrthoDBi EOG6V4GKB.

Enzyme and pathway databases

BioCyci RTYP257363:GJEQ-677-MONOMER.

Family and domain databases

Gene3Di 3.90.470.10. 1 hit.
HAMAPi MF_01331_B. Ribosomal_L22_B.
InterProi IPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view ]
PANTHERi PTHR13501. PTHR13501. 1 hit.
Pfami PF00237. Ribosomal_L22. 1 hit.
[Graphical view ]
SUPFAMi SSF54843. SSF54843. 1 hit.
TIGRFAMsi TIGR01044. rplV_bact. 1 hit.
PROSITEi PS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiRL22_RICTY
AccessioniPrimary (citable) accession number: Q68W83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2004
Last modified: October 1, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3