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Protein

50S ribosomal protein L22

Gene

rplV

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).UniRule annotation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-677-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L22UniRule annotation
Gene namesi
Name:rplVUniRule annotation
Ordered Locus Names:RT0646
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11911950S ribosomal protein L22PRO_0000243200Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi257363.RT0646.

Structurei

3D structure databases

ProteinModelPortaliQ68W83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L22P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0091.
HOGENOMiHOG000205046.
KOiK02890.
OMAiGRAFRIN.
OrthoDBiEOG6V4GKB.

Family and domain databases

Gene3Di3.90.470.10. 1 hit.
HAMAPiMF_01331_B. Ribosomal_L22_B.
InterProiIPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68W83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQENKNFAT AKAKSIRVSP RKLNLVASFI RNMKVSEALI QLTFSPKRIA
60 70 80 90 100
KIVKDCLRSA VANAENNLGL DIDRLIITKA TVGKSVVMKR IMPRAKGRAT
110
RINKFFSNLD ITVTEKEDN
Length:119
Mass (Da):13,345
Last modified:October 11, 2004 - v1
Checksum:iC82FF54CA899ECBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU04109.1.
RefSeqiWP_011191086.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU04109; AAU04109; RT0646.
KEGGirty:RT0646.
PATRICi17910534. VBIRicTyp34752_0666.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU04109.1.
RefSeqiWP_011191086.1. NC_006142.1.

3D structure databases

ProteinModelPortaliQ68W83.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi257363.RT0646.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAU04109; AAU04109; RT0646.
KEGGirty:RT0646.
PATRICi17910534. VBIRicTyp34752_0666.

Phylogenomic databases

eggNOGiCOG0091.
HOGENOMiHOG000205046.
KOiK02890.
OMAiGRAFRIN.
OrthoDBiEOG6V4GKB.

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-677-MONOMER.

Family and domain databases

Gene3Di3.90.470.10. 1 hit.
HAMAPiMF_01331_B. Ribosomal_L22_B.
InterProiIPR001063. Ribosomal_L22.
IPR018260. Ribosomal_L22/L17_CS.
IPR005727. Ribosomal_L22_bac/chlpt-type.
[Graphical view]
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiPF00237. Ribosomal_L22. 1 hit.
[Graphical view]
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01044. rplV_bact. 1 hit.
PROSITEiPS00464. RIBOSOMAL_L22. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiRL22_RICTY
AccessioniPrimary (citable) accession number: Q68W83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: October 11, 2004
Last modified: July 22, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.