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Q68W81

- RL2_RICTY

UniProt

Q68W81 - RL2_RICTY

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Protein

50S ribosomal protein L2

Gene

rplB

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro
  3. transferase activity Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-679-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L2UniRule annotation
Gene namesi
Name:rplBUniRule annotation
Ordered Locus Names:RT0648
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. large ribosomal subunit Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 27327350S ribosomal protein L2PRO_0000237236Add
BLAST

Proteomic databases

PRIDEiQ68W81.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi257363.RT0648.

Structurei

3D structure databases

ProteinModelPortaliQ68W81.
SMRiQ68W81. Positions 39-266.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L2P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0090.
HOGENOMiHOG000232982.
KOiK02886.
OMAiHKGIRPS.
OrthoDBiEOG6TR0J1.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
4.10.950.10. 1 hit.
HAMAPiMF_01320_B. Ribosomal_L2_B.
InterProiIPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR005880. Ribosomal_L2_bac/org-type.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERiPTHR13691. PTHR13691. 1 hit.
PTHR13691:SF5. PTHR13691:SF5. 1 hit.
PfamiPF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002158. Ribosomal_L2. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR01171. rplB_bact. 1 hit.
PROSITEiPS00467. RIBOSOMAL_L2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68W81-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALKNFNPIT PSLRELVQVD KTNLWKGRPL KSLTKGMSKT GGRNQQGRIT
60 70 80 90 100
SWHRGGGHKK LYRVIDFKRK KIDIFAVVER IEYDPNRTAF IALIKYDDGE
110 120 130 140 150
YSYILAPQKL SIGDRVISSQ AADIKIGNCL PLKSIPIGTT LHNVEMKVGK
160 170 180 190 200
GGQIARSAGT SVELVGKDSG YAQIKLRSGE FRLVPLDCKA TIGSISNPDQ
210 220 230 240 250
KNINLGKAGR NRWLGWRPHV RGVAMNPIDH PHGGGEGKTS GGRHPVTPWG
260 270
FSTKGKKTRK NKRTSKFIVK KRK
Length:273
Mass (Da):30,273
Last modified:October 11, 2004 - v1
Checksum:iCE880A75607B5581
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU04111.1.
RefSeqiYP_067593.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU04111; AAU04111; RT0648.
GeneIDi2959162.
KEGGirty:RT0648.
PATRICi17910538. VBIRicTyp34752_0668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017197 Genomic DNA. Translation: AAU04111.1 .
RefSeqi YP_067593.1. NC_006142.1.

3D structure databases

ProteinModelPortali Q68W81.
SMRi Q68W81. Positions 39-266.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0648.

Proteomic databases

PRIDEi Q68W81.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU04111 ; AAU04111 ; RT0648 .
GeneIDi 2959162.
KEGGi rty:RT0648.
PATRICi 17910538. VBIRicTyp34752_0668.

Phylogenomic databases

eggNOGi COG0090.
HOGENOMi HOG000232982.
KOi K02886.
OMAi HKGIRPS.
OrthoDBi EOG6TR0J1.

Enzyme and pathway databases

BioCyci RTYP257363:GJEQ-679-MONOMER.

Family and domain databases

Gene3Di 2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
4.10.950.10. 1 hit.
HAMAPi MF_01320_B. Ribosomal_L2_B.
InterProi IPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR005880. Ribosomal_L2_bac/org-type.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like.
[Graphical view ]
PANTHERi PTHR13691. PTHR13691. 1 hit.
PTHR13691:SF5. PTHR13691:SF5. 1 hit.
Pfami PF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF002158. Ribosomal_L2. 1 hit.
SUPFAMi SSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR01171. rplB_bact. 1 hit.
PROSITEi PS00467. RIBOSOMAL_L2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiRL2_RICTY
AccessioniPrimary (citable) accession number: Q68W81
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 11, 2004
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3