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Q68W81

- RL2_RICTY

UniProt

Q68W81 - RL2_RICTY

Protein

50S ribosomal protein L2

Gene

rplB

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro
    3. transferase activity Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-679-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L2UniRule annotation
    Gene namesi
    Name:rplBUniRule annotation
    Ordered Locus Names:RT0648
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. large ribosomal subunit Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 27327350S ribosomal protein L2PRO_0000237236Add
    BLAST

    Proteomic databases

    PRIDEiQ68W81.

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

    Protein-protein interaction databases

    STRINGi257363.RT0648.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68W81.
    SMRiQ68W81. Positions 39-266.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L2P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0090.
    HOGENOMiHOG000232982.
    KOiK02886.
    OMAiHKGIRPS.
    OrthoDBiEOG6TR0J1.

    Family and domain databases

    Gene3Di2.30.30.30. 1 hit.
    2.40.50.140. 1 hit.
    4.10.950.10. 1 hit.
    HAMAPiMF_01320_B. Ribosomal_L2_B.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR022666. Rbsml_prot_L2_RNA-bd_dom.
    IPR014722. Rib_L2_dom2.
    IPR002171. Ribosomal_L2.
    IPR005880. Ribosomal_L2_bac/org-type.
    IPR022669. Ribosomal_L2_C.
    IPR022671. Ribosomal_L2_CS.
    IPR014726. Ribosomal_L2_dom3.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view]
    PANTHERiPTHR13691. PTHR13691. 1 hit.
    PTHR13691:SF5. PTHR13691:SF5. 1 hit.
    PfamiPF00181. Ribosomal_L2. 1 hit.
    PF03947. Ribosomal_L2_C. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002158. Ribosomal_L2. 1 hit.
    SUPFAMiSSF50104. SSF50104. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR01171. rplB_bact. 1 hit.
    PROSITEiPS00467. RIBOSOMAL_L2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q68W81-1 [UniParc]FASTAAdd to Basket

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    MALKNFNPIT PSLRELVQVD KTNLWKGRPL KSLTKGMSKT GGRNQQGRIT    50
    SWHRGGGHKK LYRVIDFKRK KIDIFAVVER IEYDPNRTAF IALIKYDDGE 100
    YSYILAPQKL SIGDRVISSQ AADIKIGNCL PLKSIPIGTT LHNVEMKVGK 150
    GGQIARSAGT SVELVGKDSG YAQIKLRSGE FRLVPLDCKA TIGSISNPDQ 200
    KNINLGKAGR NRWLGWRPHV RGVAMNPIDH PHGGGEGKTS GGRHPVTPWG 250
    FSTKGKKTRK NKRTSKFIVK KRK 273
    Length:273
    Mass (Da):30,273
    Last modified:October 11, 2004 - v1
    Checksum:iCE880A75607B5581
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04111.1.
    RefSeqiYP_067593.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU04111; AAU04111; RT0648.
    GeneIDi2959162.
    KEGGirty:RT0648.
    PATRICi17910538. VBIRicTyp34752_0668.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04111.1 .
    RefSeqi YP_067593.1. NC_006142.1.

    3D structure databases

    ProteinModelPortali Q68W81.
    SMRi Q68W81. Positions 39-266.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0648.

    Proteomic databases

    PRIDEi Q68W81.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU04111 ; AAU04111 ; RT0648 .
    GeneIDi 2959162.
    KEGGi rty:RT0648.
    PATRICi 17910538. VBIRicTyp34752_0668.

    Phylogenomic databases

    eggNOGi COG0090.
    HOGENOMi HOG000232982.
    KOi K02886.
    OMAi HKGIRPS.
    OrthoDBi EOG6TR0J1.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-679-MONOMER.

    Family and domain databases

    Gene3Di 2.30.30.30. 1 hit.
    2.40.50.140. 1 hit.
    4.10.950.10. 1 hit.
    HAMAPi MF_01320_B. Ribosomal_L2_B.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR022666. Rbsml_prot_L2_RNA-bd_dom.
    IPR014722. Rib_L2_dom2.
    IPR002171. Ribosomal_L2.
    IPR005880. Ribosomal_L2_bac/org-type.
    IPR022669. Ribosomal_L2_C.
    IPR022671. Ribosomal_L2_CS.
    IPR014726. Ribosomal_L2_dom3.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view ]
    PANTHERi PTHR13691. PTHR13691. 1 hit.
    PTHR13691:SF5. PTHR13691:SF5. 1 hit.
    Pfami PF00181. Ribosomal_L2. 1 hit.
    PF03947. Ribosomal_L2_C. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002158. Ribosomal_L2. 1 hit.
    SUPFAMi SSF50104. SSF50104. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR01171. rplB_bact. 1 hit.
    PROSITEi PS00467. RIBOSOMAL_L2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiRL2_RICTY
    AccessioniPrimary (citable) accession number: Q68W81
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2006
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Ribosomal proteins
      Ribosomal proteins families and list of entries
    2. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3