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Q68W38

- LOLD_RICTY

UniProt

Q68W38 - LOLD_RICTY

Protein

Lipoprotein-releasing system ATP-binding protein LolD

Gene

lolD

Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi42 – 498ATPUniRule annotation

    GO - Molecular functioni

    1. ATPase activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. lipoprotein transporter activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRTYP257363:GJEQ-729-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lipoprotein-releasing system ATP-binding protein LolDUniRule annotation (EC:3.6.3.-UniRule annotation)
    Gene namesi
    Name:lolDUniRule annotation
    Ordered Locus Names:RT0695
    OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
    Taxonomic identifieri257363 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
    ProteomesiUP000000604: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Lipoprotein-releasing system ATP-binding protein LolDPRO_0000260198Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).UniRule annotation

    Protein-protein interaction databases

    STRINGi257363.RT0695.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68W38.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 220215ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1136.
    KOiK09810.
    OMAiQGNTIVK.
    OrthoDBiEOG6T7N3V.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR015854. ABC_transpr_LolD.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00005. ABC_tran. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51244. LOLD. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q68W38-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNNTVLILKK ISKHYKQGNT IVKVLDDLNL TANEGELIAI IGSSGSGKST    50
    LLHIAGLLDK PTNGQVIIPN SKYKKYHLIR LYYLGFIYQQ HHLLKDFTAL 100
    ENVIIPRLIR GLDQKEAIRD ATKILDDLGL EKKLYNMPGE LSGGEQQRVA 150
    IARSLINKPR IILADEPTGN LDPKSTNEVF NLFLKVAQKQ NTTVIMVTHN 200
    HELAHKMDKL YNLKNGLLNI A 221
    Length:221
    Mass (Da):24,812
    Last modified:October 11, 2004 - v1
    Checksum:i9B293B7F449F1C29
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04154.1.
    RefSeqiYP_067636.1. NC_006142.1.

    Genome annotation databases

    EnsemblBacteriaiAAU04154; AAU04154; RT0695.
    GeneIDi2958968.
    KEGGirty:RT0695.
    PATRICi17910636. VBIRicTyp34752_0713.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017197 Genomic DNA. Translation: AAU04154.1 .
    RefSeqi YP_067636.1. NC_006142.1.

    3D structure databases

    ProteinModelPortali Q68W38.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 257363.RT0695.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAU04154 ; AAU04154 ; RT0695 .
    GeneIDi 2958968.
    KEGGi rty:RT0695.
    PATRICi 17910636. VBIRicTyp34752_0713.

    Phylogenomic databases

    eggNOGi COG1136.
    KOi K09810.
    OMAi QGNTIVK.
    OrthoDBi EOG6T7N3V.

    Enzyme and pathway databases

    BioCyci RTYP257363:GJEQ-729-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR015854. ABC_transpr_LolD.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00005. ABC_tran. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51244. LOLD. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-144 / Wilmington.

    Entry informationi

    Entry nameiLOLD_RICTY
    AccessioniPrimary (citable) accession number: Q68W38
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Rickettsia typhi
      Rickettsia typhi (strain Wilmington): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3