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Q68W38 (LOLD_RICTY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipoprotein-releasing system ATP-binding protein LolD

EC=3.6.3.-
Gene names
Name:lolD
Ordered Locus Names:RT0695
OrganismRickettsia typhi (strain ATCC VR-144 / Wilmington) [Complete proteome] [HAMAP]
Taxonomic identifier257363 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE) By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification]

Contains 1 ABC transporter domain.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

lipoprotein transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Lipoprotein-releasing system ATP-binding protein LolD
PRO_0000260198

Regions

Domain6 – 220215ABC transporter
Nucleotide binding42 – 498ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q68W38 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 9B293B7F449F1C29

FASTA22124,812
        10         20         30         40         50         60 
MNNTVLILKK ISKHYKQGNT IVKVLDDLNL TANEGELIAI IGSSGSGKST LLHIAGLLDK 

        70         80         90        100        110        120 
PTNGQVIIPN SKYKKYHLIR LYYLGFIYQQ HHLLKDFTAL ENVIIPRLIR GLDQKEAIRD 

       130        140        150        160        170        180 
ATKILDDLGL EKKLYNMPGE LSGGEQQRVA IARSLINKPR IILADEPTGN LDPKSTNEVF 

       190        200        210        220 
NLFLKVAQKQ NTTVIMVTHN HELAHKMDKL YNLKNGLLNI A 

« Hide

References

[1]"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."
McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. expand/collapse author list , Hong C., Yu X.-J., Walker D.H., Weinstock G.M.
J. Bacteriol. 186:5842-5855(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017197 Genomic DNA. Translation: AAU04154.1.
RefSeqYP_067636.1. NC_006142.1.

3D structure databases

ProteinModelPortalQ68W38.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING257363.RT0695.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAU04154; AAU04154; RT0695.
GeneID2958968.
KEGGrty:RT0695.
PATRIC17910636. VBIRicTyp34752_0713.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1136.
KOK09810.
OMAQGNTIVK.
OrthoDBEOG6T7N3V.
ProtClustDBCLSK871039.

Enzyme and pathway databases

BioCycRTYP257363:GJEQ-729-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015854. ABC_transpr_LolD.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51244. LOLD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLOLD_RICTY
AccessionPrimary (citable) accession number: Q68W38
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Rickettsia typhi

Rickettsia typhi (strain Wilmington): entries and gene names