Reviewed, UniProtKB/Swiss-Prot Q68W05 (GLRX2_RICTY)

Names and origin

Protein names

Recommended name:
    Probable monothiol glutaredoxin-2

Gene names

Name:	grxC2
Synonyms:	grlA
Ordered Locus Names:	RT0730

Organism

Rickettsia typhi [Complete proteome] [HAMAP]

Taxonomic identifier

785 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › typhus group

Protein attributes

Sequence length	111 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the glutaredoxin family. Monothiol subfamily. Contains 1 glutaredoxin domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Domain	Redox-active center
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 111	111	Probable monothiol glutaredoxin-2		PRO_0000288733
Regions
	Domain	7 – 109	103	Glutaredoxin
Sites
	Active site	32	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q68W05-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 29A88F606B8A05E1	FASTA	111	12,637
	10 20 30 40 50 60 MMENKNLKFI QNAIKKNKVV LFMKGTKEMP ACGFSGTVVA ILNKLGVEFS DINVLFDTSL 70 80 90 100 110 REDLKKFSDW PTFPQLYING ELVGGCDIVK ELYQNGELEK MLKDETKLIK N

References

[1]

"Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae." McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A. , Hong C., Yu X.-J., Walker D.H., Weinstock G.M. J. Bacteriol. 186:5842-5855(2004) [PubMed: 15317790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC VR-144 / Wilmington.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017197 Genomic DNA. Translation: AAU04187.1.
RefSeq	YP_067669.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2959258.
GenomeReviews	Gene locus RT0730 in contig AE017197_GR.
KEGG	rty:RT0730.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q68W05.
OMA	Q68W05. DIVKEMY.
Enzyme and pathway databases
BioCyc	RTYP257363:RT0730-MON.
Family and domain databases
InterPro	IPR002109. Glutaredoxin. IPR004480. Glutredox-rel. IPR014434. Monothiol_GRX. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
PANTHER	PTHR10293. Glutredox-rel. 1 hit.
Pfam	PF00462. Glutaredoxin. 1 hit. [Graphical view]
PIRSF	PIRSF005894. Monothiol_GRX. 1 hit.
TIGRFAMs	TIGR00365. Glutredox-rel. 1 hit.
PROSITE	PS51354. GLUTAREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLRX2_RICTY

Accession

Primary (citable) accession number: Q68W05

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
Last sequence update:	October 11, 2004
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)