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Q68VX0

- UDG_RICTY

UniProt

Q68VX0 - UDG_RICTY

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Protein
UDP-glucose 6-dehydrogenase
Gene
udg, RT0766
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei260 – 2601 By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi2 – 1918NAD Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. UDP-glucose 6-dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. UDP-glucuronate biosynthetic process Source: UniProtKB-UniPathway
  2. polysaccharide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRTYP257363:GJEQ-806-MONOMER.
UniPathwayiUPA00038; UER00491.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucose 6-dehydrogenase (EC:1.1.1.22)
Short name:
UDP-Glc dehydrogenase
Short name:
UDP-GlcDH
Short name:
UDPGDH
Gene namesi
Name:udg
Ordered Locus Names:RT0766
OrganismiRickettsia typhi (strain ATCC VR-144 / Wilmington)
Taxonomic identifieri257363 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiatyphus group
ProteomesiUP000000604: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434UDP-glucose 6-dehydrogenase
PRO_0000281046Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi257363.RT0766.

Structurei

3D structure databases

ProteinModelPortaliQ68VX0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1004.
HOGENOMiHOG000153773.
KOiK00012.
OMAiCEMVGAN.
OrthoDBiEOG6ZSP7N.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view]
PANTHERiPTHR11374. PTHR11374. 1 hit.
PfamiPF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTiSM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsiTIGR03026. NDP-sugDHase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q68VX0-1 [UniParc]FASTAAdd to Basket

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MNITFIGSGY VGLVSGIIMG YLGHNVTCFD NDDVKISKLN KKILPIYEAK    50
LDEYLKQALE SDRLKFTNIY SNDFRNVDAV FITVGTPSKE LGEADLKYVY 100
DAVDKVSKHI NKDCLIVIKS TVPPGSCNNI IAYLKAKGFS FNVASNPEFL 150
REGSAVEDFL YPDRIVVGVN NQESEALLRT IYAPLIEQGV KFLVTNLVTS 200
ELIKYASNSF LATKIAFINE MADLCEKIGA NIKDLSQGVG LDQRIGRNFL 250
NAGPGFGGSC FPKDILALNN LVENYKIDCK ILKSVIKSNK LRPGNMVAKI 300
ATLLDGDLKG RNIAILGLTY KAGTDDVRAS PAIEIITILL NKDVYVKAFD 350
PIGLENAKKN LEHKNLLYFA SAVEACESVD IIVIATEWSE FKELNWQEIY 400
DLVKSPMIID LRNILDNEVM KKIGFRYYAV GSKI 434
Length:434
Mass (Da):48,146
Last modified:October 11, 2004 - v1
Checksum:i6BB8BA50CE45464D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU04222.1.
RefSeqiYP_067704.1. NC_006142.1.

Genome annotation databases

EnsemblBacteriaiAAU04222; AAU04222; RT0766.
GeneIDi2959383.
KEGGirty:RT0766.
PATRICi17910786. VBIRicTyp34752_0786.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017197 Genomic DNA. Translation: AAU04222.1 .
RefSeqi YP_067704.1. NC_006142.1.

3D structure databases

ProteinModelPortali Q68VX0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 257363.RT0766.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAU04222 ; AAU04222 ; RT0766 .
GeneIDi 2959383.
KEGGi rty:RT0766.
PATRICi 17910786. VBIRicTyp34752_0786.

Phylogenomic databases

eggNOGi COG1004.
HOGENOMi HOG000153773.
KOi K00012.
OMAi CEMVGAN.
OrthoDBi EOG6ZSP7N.

Enzyme and pathway databases

UniPathwayi UPA00038 ; UER00491 .
BioCyci RTYP257363:GJEQ-806-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 2 hits.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view ]
PANTHERi PTHR11374. PTHR11374. 1 hit.
Pfami PF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTi SM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsi TIGR03026. NDP-sugDHase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-144 / Wilmington.

Entry informationi

Entry nameiUDG_RICTY
AccessioniPrimary (citable) accession number: Q68VX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 11, 2004
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Rickettsia typhi
    Rickettsia typhi (strain Wilmington): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi