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Protein
Submitted name:

Voltage-gated sodium channel alpha subunit Nav1.3

Gene

Scn3a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-gated sodium channel alpha subunit Nav1.3Imported
Gene namesi
Name:Scn3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98249 Scn3a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei54 – 72HelicalSequence analysisAdd BLAST19
Transmembranei84 – 102HelicalSequence analysisAdd BLAST19
Transmembranei109 – 134HelicalSequence analysisAdd BLAST26
Transmembranei171 – 199HelicalSequence analysisAdd BLAST29

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ68V26

Structurei

3D structure databases

ProteinModelPortaliQ68V26
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 218Ion_transInterPro annotationAdd BLAST166

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG2301 Eukaryota
ENOG410XNP6 LUCA
HOGENOMiHOG000231755

Family and domain databases

Gene3Di1.20.120.3501 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL

Sequencei

Sequence statusi: Fragment.

Q68V26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QKKKFGGQDI FMTEEQKKYY NAMKKLGSKK PQKPIPRPAN KFQGMVFDFV
60 70 80 90 100
TRQVFDISIM ILICLNMVTM MVETDDQSKY MTLVLSRINL VFIVLFTGEF
110 120 130 140 150
LLKLISLRYY YFTIGWNIFD FVVVILSIVG MFLAELIEKY FVSPTLFRVI
160 170 180 190 200
RLARIGRILR LIKGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYAIFG
210 220
MSNFAYVKKE AGIDDMFNFE
Length:220
Mass (Da):25,603
Last modified:October 11, 2004 - v1
Checksum:i321C149A098F54DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei220Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ810517 mRNA Translation: CAH17961.1
UniGeneiMm.330256

Similar proteinsi

Entry informationi

Entry nameiQ68V26_MOUSE
AccessioniPrimary (citable) accession number: Q68V26
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: April 25, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)