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Q68V26

- Q68V26_MOUSE

UniProt

Q68V26 - Q68V26_MOUSE

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Protein
Submitted name: Voltage-gated sodium channel alpha subunit Nav1.3
Gene
Scn3a
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. potassium channel activity Source: UniProtKB-KW
  2. voltage-gated sodium channel activity Source: RefGenome
Complete GO annotation...

GO - Biological processi

  1. membrane depolarization during action potential Source: RefGenome
  2. neuronal action potential Source: RefGenome
  3. sodium ion transmembrane transport Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotations, Voltage-gated channelSAAS annotations

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-gated sodium channel alpha subunit Nav1.3Imported
Gene namesi
Name:Scn3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98249. Scn3a.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. membrane Source: MGI
  3. plasma membrane Source: RefGenome
  4. voltage-gated sodium channel complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

ArrayExpressiQ68V26.
BgeeiQ68V26.
GenevestigatoriQ68V26.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ68V26.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOGENOMiHOG000231755.
InParanoidiQ68V26.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR028808. Na_channel_a3su.
[Graphical view]
PANTHERiPTHR10037:SF200. PTHR10037:SF200. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.

Sequencei

Sequence statusi: Fragment.

Q68V26-1 [UniParc]FASTAAdd to Basket

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QKKKFGGQDI FMTEEQKKYY NAMKKLGSKK PQKPIPRPAN KFQGMVFDFV    50
TRQVFDISIM ILICLNMVTM MVETDDQSKY MTLVLSRINL VFIVLFTGEF 100
LLKLISLRYY YFTIGWNIFD FVVVILSIVG MFLAELIEKY FVSPTLFRVI 150
RLARIGRILR LIKGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYAIFG 200
MSNFAYVKKE AGIDDMFNFE 220
Length:220
Mass (Da):25,603
Last modified:October 11, 2004 - v1
Checksum:i321C149A098F54DA
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei220 – 2201Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ810517 mRNA. Translation: CAH17961.1.
UniGeneiMm.330256.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ810517 mRNA. Translation: CAH17961.1 .
UniGenei Mm.330256.

3D structure databases

ProteinModelPortali Q68V26.
ModBasei Search...

Chemistry

BindingDBi Q68V26.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:98249. Scn3a.

Phylogenomic databases

HOGENOMi HOG000231755.
InParanoidi Q68V26.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q68V26.
Bgeei Q68V26.
Genevestigatori Q68V26.

Family and domain databases

Gene3Di 1.20.120.350. 1 hit.
InterProi IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR028808. Na_channel_a3su.
[Graphical view ]
PANTHERi PTHR10037:SF200. PTHR10037:SF200. 1 hit.
Pfami PF00520. Ion_trans. 1 hit.
[Graphical view ]
PRINTSi PR00169. KCHANNEL.
ProtoNeti Search...

Publicationsi

  1. "Expression pattern of neuronal and skeletal muscle voltage-gated sodium channels in the developing mouse heart."
    Haufe V., Camacho J.A., Guenther B., Dumaine R., Bollensdorff C., Segond von Banchet G., Benndorf K., Zimmer T.
    Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: HeartImported.

Entry informationi

Entry nameiQ68V26_MOUSE
AccessioniPrimary (citable) accession number: Q68V26
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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