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Protein
Submitted name:

Voltage-gated sodium channel alpha subunit Nav1.3

Gene

Scn3a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-gated sodium channel alpha subunit Nav1.3Imported
Gene namesi
Name:Scn3aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98249. Scn3a.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei54 – 72HelicalSequence analysisAdd BLAST19
Transmembranei84 – 102HelicalSequence analysisAdd BLAST19
Transmembranei109 – 134HelicalSequence analysisAdd BLAST26
Transmembranei171 – 199HelicalSequence analysisAdd BLAST29

GO - Cellular componenti

  • cytoplasm Source: MGI
  • membrane Source: MGI
  • voltage-gated potassium channel complex Source: InterPro

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ68V26.
PeptideAtlasiQ68V26.

Structurei

3D structure databases

ProteinModelPortaliQ68V26.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 218Ion_transInterPro annotationAdd BLAST166

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG2301. Eukaryota.
ENOG410XNP6. LUCA.
HOGENOMiHOG000231755.

Family and domain databases

InterProiView protein in InterPro
IPR005821. Ion_trans_dom.
IPR028325. VG_K_chnl.
PfamiView protein in Pfam
PF00520. Ion_trans. 1 hit.
PRINTSiPR00169. KCHANNEL.

Sequencei

Sequence statusi: Fragment.

Q68V26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QKKKFGGQDI FMTEEQKKYY NAMKKLGSKK PQKPIPRPAN KFQGMVFDFV
60 70 80 90 100
TRQVFDISIM ILICLNMVTM MVETDDQSKY MTLVLSRINL VFIVLFTGEF
110 120 130 140 150
LLKLISLRYY YFTIGWNIFD FVVVILSIVG MFLAELIEKY FVSPTLFRVI
160 170 180 190 200
RLARIGRILR LIKGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYAIFG
210 220
MSNFAYVKKE AGIDDMFNFE
Length:220
Mass (Da):25,603
Last modified:October 11, 2004 - v1
Checksum:i321C149A098F54DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei220Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ810517 mRNA. Translation: CAH17961.1.
UniGeneiMm.330256.

Similar proteinsi

Entry informationi

Entry nameiQ68V26_MOUSE
AccessioniPrimary (citable) accession number: Q68V26
Entry historyiIntegrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: August 30, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)