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Protein

Alpha-(1,3)-fucosyltransferase 11

Gene

Fut11

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable fucosyltransferase.By similarity

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-(1,3)-fucosyltransferase 11 (EC:2.4.1.-)
Alternative name(s):
Fucosyltransferase XI
Short name:
Fuc-TXI
Short name:
FucT-XI
Galactoside 3-L-fucosyltransferase 11
Short name:
Fucosyltransferase 11
Gene namesi
Name:Fut11
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi628731. Fut11.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 7CytoplasmicSequence analysis7
Transmembranei8 – 24Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST17
Topological domaini25 – 494LumenalSequence analysisAdd BLAST470

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002990111 – 494Alpha-(1,3)-fucosyltransferase 11Add BLAST494

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi99 ↔ 104By similarity
Glycosylationi167N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi390 ↔ 393By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ68FV3.
PRIDEiQ68FV3.

PTM databases

PhosphoSitePlusiQ68FV3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000009274.
GenevisibleiQ68FV3. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012300.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 10 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
GeneTreeiENSGT00680000099679.
HOGENOMiHOG000006538.
HOVERGENiHBG055521.
InParanoidiQ68FV3.
KOiK11257.
OMAiKFWDYLH.
OrthoDBiEOG091G064Z.
PhylomeDBiQ68FV3.
TreeFamiTF316348.

Family and domain databases

InterProiIPR017176. Alpha-1_3-FUT_met.
IPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PANTHERiPTHR11929. PTHR11929. 1 hit.
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF037332. Alpha1_3FUT_met. 1 hit.

Sequencei

Sequence statusi: Complete.

Q68FV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARYTEAVL AALGVLSVCS ASSSSGSGAS GKAGGEAEWA EPWDGAVFRP
60 70 80 90 100
PAALGAVGMT RGLGSPPPGN AETVDLPVLL WWSPGLFPHF PGDSERIECA
110 120 130 140 150
LGACVASRDR RARADPRTRA LLFYGTDFRA ADAPLPRLAH QSWALLHEES
160 170 180 190 200
PLNNFLLSHG PGIRLFNLTA TFSRHSDYPL PLQWLPGAAY LRRPAPPLRE
210 220 230 240 250
RAEWRRRGYA PLLYLQSHCD VPSDRDRYVR ELMRYIPVDS YGKCLQNREP
260 270 280 290 300
PTVRLQDTAT ATTEDPELMA FLSRYKFHLA MENAICNDYM TEKLWRPMHL
310 320 330 340 350
GAVPVYRGSP SVRDWMPNNH SVILIDDFES PQKLAEFIDF LDKNDEEYMK
360 370 380 390 400
YLAYKQPGGI TNQFLLDNLE HREWGVNDPM LPNYLNGFEC FVCDHELARL
410 420 430 440 450
DAEKAHESSP RDIPVLEPHI AQLSHMDCPV PTPGFGKVEE IPENDSWKEM
460 470 480 490
WLQDYWQGLY QGEALTAMIH NNETQQSKFW DYVHEIFMKR NKNL
Length:494
Mass (Da):56,000
Last modified:October 11, 2004 - v1
Checksum:i6EA3AB50641272D4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti41 – 42EP → A in CAD59737 (Ref. 1) Curated2
Sequence conflicti281 – 283MEN → LEK in CAD59737 (Ref. 1) Curated3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ535753 mRNA. Translation: CAD59737.1.
BC079316 mRNA. Translation: AAH79316.1.
RefSeqiNP_775430.2. NM_173308.2.
UniGeneiRn.24040.

Genome annotation databases

EnsembliENSRNOT00000012300; ENSRNOP00000012300; ENSRNOG00000009274.
GeneIDi286971.
KEGGirno:286971.
UCSCiRGD:628731. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ535753 mRNA. Translation: CAD59737.1.
BC079316 mRNA. Translation: AAH79316.1.
RefSeqiNP_775430.2. NM_173308.2.
UniGeneiRn.24040.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000012300.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

PTM databases

PhosphoSitePlusiQ68FV3.

Proteomic databases

PaxDbiQ68FV3.
PRIDEiQ68FV3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000012300; ENSRNOP00000012300; ENSRNOG00000009274.
GeneIDi286971.
KEGGirno:286971.
UCSCiRGD:628731. rat.

Organism-specific databases

CTDi170384.
RGDi628731. Fut11.

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
GeneTreeiENSGT00680000099679.
HOGENOMiHOG000006538.
HOVERGENiHBG055521.
InParanoidiQ68FV3.
KOiK11257.
OMAiKFWDYLH.
OrthoDBiEOG091G064Z.
PhylomeDBiQ68FV3.
TreeFamiTF316348.

Enzyme and pathway databases

UniPathwayiUPA00378.

Miscellaneous databases

PROiQ68FV3.

Gene expression databases

BgeeiENSRNOG00000009274.
GenevisibleiQ68FV3. RN.

Family and domain databases

InterProiIPR017176. Alpha-1_3-FUT_met.
IPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PANTHERiPTHR11929. PTHR11929. 1 hit.
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF037332. Alpha1_3FUT_met. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFUT11_RAT
AccessioniPrimary (citable) accession number: Q68FV3
Secondary accession number(s): Q8CG40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: October 11, 2004
Last modified: November 2, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.