Reviewed, UniProtKB/Swiss-Prot Q68FE2 (ATG9A_MOUSE)

Names and origin

Protein names

Recommended name:
    Autophagy-related protein 9A
Alternative name(s):
    APG9-like 1

Gene names

Name:	Atg9a
Synonyms:	Apg9l1

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Plays a role in autophagy By similarity.
Subcellular location	Cytoplasmic vesicle › autophagosome membrane; Multi-pass membrane protein By similarity.
Miscellaneous	Isoform displayed in this entry matches to human isoform 3.
Sequence similarities	Belongs to the ATG9 family.

Ontologies

Keywords
Biological process	Autophagy Protein transport Transport
Cellular component	Cytoplasmic vesicle Membrane
Domain	Transmembrane
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	autophagy Inferred from electronic annotation. Source: UniProtKB-KW protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	autophagic vacuole Inferred from direct assay. Source: MGI cytoplasmic vesicle Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 551	551	Autophagy-related protein 9A		PRO_0000119821
Regions
	Transmembrane	73 – 93	21	Potential
	Transmembrane	132 – 152	21	Potential
	Transmembrane	290 – 310	21	Potential
	Transmembrane	372 – 392	21	Potential
	Transmembrane	401 – 421	21	Potential
Amino acid modifications
	Modified residue	14	1	Phosphoserine By similarity
	Modified residue	18	1	Phosphoserine By similarity
	Modified residue	524	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q68FE2-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: BDCDBA33E0D10C26	FASTA	551	63,138
	10 20 30 40 50 60 MAQFDTEYQR LEASYSDSPP GEEDLLVHVA EGSKSPWHHI ENLDLFFSRV YNLHQKNGFT 70 80 90 100 110 120 CMLIGEMFEL MQFLFVVAFT TFLVSCVDYD ILFANKMVNH SLHPTEPVKV TLPDAFLPAQ 130 140 150 160 170 180 VCSARIQENG SLITILVIAG VFWIHRLIKF IYNICCYWEI HSFYLHALRI PMSALPYCTW 190 200 210 220 230 240 QEVQARIVQT QKEHQICIHK RELTELDIYH RILRFQNYMV ALVNKSLLPL RFRLPGLGEV 250 260 270 280 290 300 VFFTRGLKYN FELILFWGPG SLFLNEWSLK AEYKRGGQRL ELAQRLSNRI LWIGIANFLL 310 320 330 340 350 360 CPLILIWQIL YAFFSYAEVL KREPGALGAR CWSLYGRCYL RHFNELEHEL QSRLNRGYKP 370 380 390 400 410 420 ASKYMNCFLS PLLTLLAKNG AFFAGSILAV LIALTIYDED VLAVEHVLTT VTLLGVTVTV 430 440 450 460 470 480 CRSFIPDQHM VFCPEQLLRV ILAHIHYMPD HWQGVHLGGV AESHRHTPHS HLLPPPSGPG 490 500 510 520 530 540 DHRLLPQLYG RGRGCGRHLL LCSDGRSPAW PSSVAVWRAD RGLSVPASRG REDRVVAHAL 550 CHHQSRLAAP S

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6. Tissue: Brain.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC079884 mRNA. Translation: AAH79884.1.
IPI	IPI00461470.
UniGene	Mm.475691
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q68FE2.
Proteomic databases
PRIDE	Q68FE2.
Organism-specific databases
MGI	MGI:2138446. Atg9a.
Gene expression databases
CleanEx	MM_ATG9A.
Genevestigator	Q68FE2.
GermOnline	ENSMUSG00000033124. Mus musculus.
Family and domain databases
InterPro	IPR007241. Autophagy-rel_prot_9. [Graphical view]
PANTHER	PTHR13038. APG9. 1 hit.
Pfam	PF04109. APG9. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

ATG9A_MOUSE

Accession

Primary (citable) accession number: Q68FE2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 12, 2005
Last sequence update:	October 11, 2004
Last modified:	February 9, 2010
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)