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Protein
Submitted name:

Beta-arrestin-2

Gene

DKFZp686L0365

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-arrestin-2Imported
Submitted name:
Putative uncharacterized protein DKFZp686L0365Imported
Submitted name:
cDNA FLJ58316, highly similar to Beta-arrestin-2Imported
Gene namesi
Name:DKFZp686L0365Imported
Synonyms:ARRB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

HGNCiHGNC:712. ARRB2.

PTM / Processingi

Proteomic databases

EPDiQ68DZ5.
PaxDbiQ68DZ5.

Expressioni

Gene expression databases

ExpressionAtlasiQ68DZ5. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ68DZ5. 1 interaction.
MINTiMINT-1381979.
STRINGi9606.ENSP00000269260.

Structurei

3D structure databases

ProteinModelPortaliQ68DZ5.
SMRiQ68DZ5. Positions 1-208.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 157156Arrestin_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3865. Eukaryota.
ENOG410XR0F. LUCA.
GeneTreeiENSGT00390000013152.
HOVERGENiHBG002399.

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
InterProiIPR000698. Arrestin.
IPR014752. Arrestin_C.
IPR011022. Arrestin_C-like.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PfamiPF02752. Arrestin_C. 1 hit.
[Graphical view]
SMARTiSM01017. Arrestin_C. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q68DZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDRSLHLEA SLDKELYYHG EPLNVNVHVT NNSTKTVKKI KVSVRQYADI
60 70 80 90 100
CLFSTAQYKC PVAQLEQDDQ VSPSSTFCKV YTITPLLSDN REKRGLALDG
110 120 130 140 150
KLKHEDTNLA SSTIVKEGAN KEVLGILVSY RVKVKLVVSR GGDVSVELPF
160 170 180 190 200
VLMHPKPHDH IPLPRPQSAA PETDVPVDTN LIEFDTNYAT DDDIVFEDFA
210
RLRLKGMKDD DYDDQLC
Length:217
Mass (Da):24,363
Last modified:October 11, 2004 - v1
Checksum:i61653F5BABCBB0FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091153 Genomic DNA. No translation available.
AK297059 mRNA. Translation: BAG59581.1.
CR749218 mRNA. Translation: CAH18075.1.
RefSeqiXP_006721583.1. XM_006721520.1.
XP_006721584.1. XM_006721521.1.
UniGeneiHs.435811.

Genome annotation databases

EnsembliENST00000571206; ENSP00000460607; ENSG00000141480.
ENST00000572457; ENSP00000465296; ENSG00000141480.
ENST00000574954; ENSP00000466344; ENSG00000141480.
GeneIDi409.
UCSCiuc002fyn.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC091153 Genomic DNA. No translation available.
AK297059 mRNA. Translation: BAG59581.1.
CR749218 mRNA. Translation: CAH18075.1.
RefSeqiXP_006721583.1. XM_006721520.1.
XP_006721584.1. XM_006721521.1.
UniGeneiHs.435811.

3D structure databases

ProteinModelPortaliQ68DZ5.
SMRiQ68DZ5. Positions 1-208.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ68DZ5. 1 interaction.
MINTiMINT-1381979.
STRINGi9606.ENSP00000269260.

Proteomic databases

EPDiQ68DZ5.
PaxDbiQ68DZ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000571206; ENSP00000460607; ENSG00000141480.
ENST00000572457; ENSP00000465296; ENSG00000141480.
ENST00000574954; ENSP00000466344; ENSG00000141480.
GeneIDi409.
UCSCiuc002fyn.4. human.

Organism-specific databases

CTDi409.
HGNCiHGNC:712. ARRB2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3865. Eukaryota.
ENOG410XR0F. LUCA.
GeneTreeiENSGT00390000013152.
HOVERGENiHBG002399.

Miscellaneous databases

ChiTaRSiARRB2. human.
GenomeRNAii409.

Gene expression databases

ExpressionAtlasiQ68DZ5. baseline and differential.

Family and domain databases

Gene3Di2.60.40.640. 1 hit.
InterProiIPR000698. Arrestin.
IPR014752. Arrestin_C.
IPR011022. Arrestin_C-like.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR11792. PTHR11792. 1 hit.
PfamiPF02752. Arrestin_C. 1 hit.
[Graphical view]
SMARTiSM01017. Arrestin_C. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: EndometriumImported.
  2. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Cord bloodImported.
  4. Ensembl
    Submitted (MAY-2012) to UniProtKB
    Cited for: IDENTIFICATION.
  5. Ensembl
    Submitted (NOV-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ68DZ5_HUMAN
AccessioniPrimary (citable) accession number: Q68DZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 16, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.