Unreviewed, UniProtKB/TrEMBL Q68DS8 (Q68DS8_HUMAN)

Names and origin

Protein names

Submitted name:
    Putative uncharacterized protein DKFZp686J10186 EMBL CAH18142.1

Gene names

Name:

DKFZp686J10186 EMBL CAH18142.1

Organism

Homo sapiens (Human) EMBL CAH18142.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	42 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	SMAD protein complex assembly Inferred from electronic annotation. Source: Compara T cell activation Inferred from electronic annotation. Source: Compara activation of pro-apoptotic gene products Inferred from electronic annotation. Source: Compara mesoderm formation Inferred from electronic annotation. Source: Compara negative regulation of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of gene-specific transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara negative regulation of osteoblast differentiation Inferred from electronic annotation. Source: Compara osteoblast development Inferred from electronic annotation. Source: Compara paraxial mesoderm morphogenesis Inferred from electronic annotation. Source: Compara positive regulation of alkaline phosphatase activity Inferred from electronic annotation. Source: Compara positive regulation of bone mineralization Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of focal adhesion assembly Inferred from electronic annotation. Source: Compara positive regulation of gene-specific transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara positive regulation of interleukin-1 beta production Inferred from electronic annotation. Source: Compara positive regulation of positive chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of stress fiber assembly Inferred from electronic annotation. Source: Compara positive regulation of transforming growth factor-beta3 production Inferred from electronic annotation. Source: Compara regulation of binding Inferred from electronic annotation. Source: Compara regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara regulation of immune response Inferred from electronic annotation. Source: Compara regulation of striated muscle tissue development Inferred from electronic annotation. Source: Compara regulation of transforming growth factor beta receptor signaling pathway Inferred from electronic annotation. Source: Compara release of cytochrome c from mitochondria Inferred from electronic annotation. Source: Compara transdifferentiation Inferred from electronic annotation. Source: Compara
Cellular component	nucleus Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Molecular function	SMAD binding Inferred from electronic annotation. Source: Compara collagen binding Inferred from electronic annotation. Source: Compara double-stranded DNA binding Inferred from electronic annotation. Source: Compara ligand-regulated transcription factor activity Inferred from electronic annotation. Source: Compara sequence-specific DNA binding Inferred from electronic annotation. Source: Compara specific transcriptional repressor activity Inferred from electronic annotation. Source: Compara transcription activator activity Inferred from electronic annotation. Source: Compara transcription factor activity Inferred from electronic annotation. Source: Compara transcription factor binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAH18142.1

Sequences

	Sequence		Length	Mass (Da)
	Q68DS8-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 63F0E13724FDCAAA	FASTA	42	4,790
	10 20 30 40 YRRQTVTSTP CWIELHLNGP LQWLDKVLTQ MGSPSIRCSS VS

References

[1]	The German cDNA Consortium Koehrer K., Beyer A., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Esophagus tumor EMBL CAH18142.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR749287 mRNA. Translation: CAH18142.1.
IPI	IPI00922049.
UniGene	Hs.718953
3D structure databases
SMR	Q68DS8. Positions 1-42.
ModBase	Search...
Protein-protein interaction databases
STRING	Q68DS8.
Genome annotation databases
Ensembl	ENST00000327367; ENSP00000332973; ENSG00000166949; Homo sapiens. [Genome view] ENST00000439724; ENSP00000401133; ENSG00000166949; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:6769. SMAD3.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q68DS8.
Gene expression databases
ArrayExpress	Q68DS8.
Bgee	Q68DS8.
Family and domain databases
InterPro	IPR013790. Dwarfin. IPR017855. SMAD_dom-like. IPR001132. SMAD_dom_Dwarfin-type. IPR008984. SMAD_FHA_domain. [Graphical view]
Gene3D	G3DSA:2.60.200.10. MH2_Dwarfin-type. 1 hit.
PANTHER	PTHR13703. Dwarfin. 1 hit.
Pfam	PF03166. MH2. 1 hit. [Graphical view]
PROSITE	PS51076. MH2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q68DS8_HUMAN

Accession

Primary (citable) accession number: Q68DS8

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	January 19, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.