Putative uncharacterized protein DKFZp686J10186

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Unreviewed, UniProtKB/TrEMBL Q68DS8 (Q68DS8_HUMAN)

Last modified January 19, 2010. Version 34. History...

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Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein names

Submitted name:
Putative uncharacterized protein DKFZp686J10186 EMBL CAH18142.1

Gene names

Name:

DKFZp686J10186 EMBL CAH18142.1

Organism

Homo sapiens (Human) EMBL CAH18142.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length	42 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

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Ontologies

Gene Ontology (GO)
Biological process	SMAD protein complex assembly Inferred from electronic annotation. Source: Compara T cell activation Inferred from electronic annotation. Source: Compara activation of pro-apoptotic gene products Inferred from electronic annotation. Source: Compara mesoderm formation Inferred from electronic annotation. Source: Compara negative regulation of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of gene-specific transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara negative regulation of osteoblast differentiation Inferred from electronic annotation. Source: Compara osteoblast development Inferred from electronic annotation. Source: Compara paraxial mesoderm morphogenesis Inferred from electronic annotation. Source: Compara positive regulation of alkaline phosphatase activity Inferred from electronic annotation. Source: Compara positive regulation of bone mineralization Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of focal adhesion assembly Inferred from electronic annotation. Source: Compara positive regulation of gene-specific transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara positive regulation of interleukin-1 beta production Inferred from electronic annotation. Source: Compara positive regulation of positive chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of stress fiber assembly Inferred from electronic annotation. Source: Compara positive regulation of transforming growth factor-beta3 production Inferred from electronic annotation. Source: Compara regulation of binding Inferred from electronic annotation. Source: Compara regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara regulation of immune response Inferred from electronic annotation. Source: Compara regulation of striated muscle tissue development Inferred from electronic annotation. Source: Compara regulation of transforming growth factor beta receptor signaling pathway Inferred from electronic annotation. Source: Compara release of cytochrome c from mitochondria Inferred from electronic annotation. Source: Compara transdifferentiation Inferred from electronic annotation. Source: Compara
Cellular component	nucleus Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Molecular function	SMAD binding Inferred from electronic annotation. Source: Compara collagen binding Inferred from electronic annotation. Source: Compara double-stranded DNA binding Inferred from electronic annotation. Source: Compara ligand-regulated transcription factor activity Inferred from electronic annotation. Source: Compara sequence-specific DNA binding Inferred from electronic annotation. Source: Compara specific transcriptional repressor activity Inferred from electronic annotation. Source: Compara transcription activator activity Inferred from electronic annotation. Source: Compara transcription factor activity Inferred from electronic annotation. Source: Compara transcription factor binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

EMBL CAH18142.1

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Sequences

Sequence

Length

Mass (Da)

Tools

Q68DS8-1 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 63F0E13724FDCAAA
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FASTA

4,790

        10         20         30         40 
YRRQTVTSTP CWIELHLNGP LQWLDKVLTQ MGSPSIRCSS VS

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References

[1]	The German cDNA Consortium Koehrer K., Beyer A., Mewes H.W., Weil B., Amid C., Osanger A., Fobo G., Han M., Wiemann S. Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Esophagus tumor EMBL CAH18142.1.
+	Additional computationally mapped references.

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Cross-references

Sequence databases
EMBL GenBank DDBJ	CR749287 mRNA. Translation: CAH18142.1.
IPI	IPI00922049.
UniGene	Hs.718953
3D structure databases
SMR	Q68DS8. Positions 1-42.
ModBase	Search...
Protein-protein interaction databases
STRING	Q68DS8.
Genome annotation databases
Ensembl	ENST00000327367; ENSP00000332973; ENSG00000166949; Homo sapiens. [Genome view] ENST00000439724; ENSP00000401133; ENSG00000166949; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:6769. SMAD3.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q68DS8.
Gene expression databases
ArrayExpress	Q68DS8.
Bgee	Q68DS8.
Family and domain databases
InterPro	IPR013790. Dwarfin. IPR017855. SMAD_dom-like. IPR001132. SMAD_dom_Dwarfin-type. IPR008984. SMAD_FHA_domain. [Graphical view]
Gene3D	G3DSA:2.60.200.10. MH2_Dwarfin-type. 1 hit.
PANTHER	PTHR13703. Dwarfin. 1 hit.
Pfam	PF03166. MH2. 1 hit. [Graphical view]
PROSITE	PS51076. MH2. 1 hit. [Graphical view]
ProtoNet	Search...

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Entry information

Entry name

Q68DS8_HUMAN

Accession

Primary (citable) accession number: Q68DS8

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	January 19, 2010
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein attributes

Ontologies

Sequence annotation (Features)

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Entry information