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Protein
Submitted name:

Putative uncharacterized protein DKFZp781F1414

Gene

DKFZp781F1414

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi195 – 1951CalciumUniRule annotation
Metal bindingi209 – 2091CalciumUniRule annotation
Metal bindingi250 – 2501CalciumUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein DKFZp781F1414Imported
Gene namesi
Name:DKFZp781F1414Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei857 – 88226HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31783.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 923902Sequence analysisPRO_5004269541Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi27 ↔ 54UniRule annotation
Disulfide bondi82 ↔ 104UniRule annotation
Disulfide bondi147 ↔ 173UniRule annotation
Disulfide bondi206 ↔ 228UniRule annotation
Disulfide bondi275 ↔ 424UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Proteomic databases

PaxDbiQ68DN3.
PRIDEiQ68DN3.

Expressioni

Gene expression databases

GenevisibleiQ68DN3. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265371.

Structurei

3D structure databases

ProteinModelPortaliQ68DN3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini27 – 141115CUBInterPro annotationAdd
BLAST
Domaini147 – 265119CUBInterPro annotationAdd
BLAST
Domaini275 – 424150F5/8 type CInterPro annotationAdd
BLAST
Domaini430 – 583154F5/8 type CInterPro annotationAdd
BLAST
Domaini648 – 811164MAMInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 2 F5/8 type C domains.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IE8T. Eukaryota.
ENOG410YRBE. LUCA.
HOVERGENiHBG000502.
KOiK06724.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
2.60.120.290. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR000859. CUB_dom.
IPR000421. FA58C.
IPR008979. Galactose-bd-like.
IPR000998. MAM_dom.
IPR014648. Neuropilin.
IPR022579. Neuropilin_C.
IPR027146. NRP1.
[Graphical view]
PANTHERiPTHR10127:SF654. PTHR10127:SF654. 1 hit.
PfamiPF00431. CUB. 2 hits.
PF11980. DUF3481. 1 hit.
PF00754. F5_F8_type_C. 2 hits.
PF00629. MAM. 1 hit.
[Graphical view]
PIRSFiPIRSF036960. Neuropilin. 1 hit.
PRINTSiPR00020. MAMDOMAIN.
SMARTiSM00042. CUB. 2 hits.
SM00231. FA58C. 2 hits.
SM00137. MAM. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 2 hits.
SSF49854. SSF49854. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiPS01180. CUB. 2 hits.
PS01285. FA58C_1. 2 hits.
PS01286. FA58C_2. 2 hits.
PS50022. FA58C_3. 2 hits.
PS00740. MAM_1. 1 hit.
PS50060. MAM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q68DN3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP
60 70 80 90 100
SEKCEWLIQA PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR
110 120 130 140 150
GKFCGKIAPP PVVSSGPFLF IKFVSDYETH GAGFSIRYEV FKRGPECSQN
160 170 180 190 200
YTTPSGVIKS PGFPEKYPNS LECTYIVFAP KMSEIILEFE SFDLEPDSNP
210 220 230 240 250
PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS GILSMVFYTD
260 270 280 290 300
SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN
310 320 330 340 350
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK
360 370 380 390 400
KKYYVKTYKI DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI
410 420 430 440 450
TRFVRIKPAT WETGISMRFE VYGCKITDYP RSGMLGMVSG LISDSQITSS
460 470 480 490 500
NQGDRNWMPE NIRLVTSRSG WALPPAPHSY INEWLQIDLG EEKIVRGIII
510 520 530 540 550
QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF EGNNNYDTPE
560 570 580 590 600
LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV
610 620 630 640 650
DECDDDQANC HSGTGDDFQL AGGTTVLATE KPTVIDSTIQ SEFPTYGFNC
660 670 680 690 700
EFGWGSHKTF CHWEHDNHVQ LKWSVLTSKT GPIQDHTGDG NFIYSQADEN
710 720 730 740 750
QKGKVARLVS PVVYSQNSAH CMTFWYHMSG SHVGTLRVKL RYQKPEEYDQ
760 770 780 790 800
LVWMAIGHQG DHWKEGRVLL HKSLKLYQVI FEGEIGKGNL GGIAVDDISI
810 820 830 840 850
NNHISQEDCA KPADLDKKNP EIKIDETGSA PGYEGEGEGD KNISRKPGNV
860 870 880 890 900
LKTLDPILIT IIAMSALGVL LGAVCGVVLY CACWHNGMSE RNLSALENYN
910 920
FELVDGVKLK KDKLNTQSTY SEA
Length:923
Mass (Da):103,085
Last modified:October 11, 2004 - v1
Checksum:iFA5033CC5B523DEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR749333 mRNA. Translation: CAH18187.1.
RefSeqiNP_001019799.1. NM_001024628.2.
NP_001019800.1. NM_001024629.2.
NP_003864.4. NM_003873.5.
UniGeneiHs.131704.
Hs.653996.

Genome annotation databases

GeneIDi8829.
KEGGihsa:8829.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR749333 mRNA. Translation: CAH18187.1.
RefSeqiNP_001019799.1. NM_001024628.2.
NP_001019800.1. NM_001024629.2.
NP_003864.4. NM_003873.5.
UniGeneiHs.131704.
Hs.653996.

3D structure databases

ProteinModelPortaliQ68DN3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265371.

Proteomic databases

PaxDbiQ68DN3.
PRIDEiQ68DN3.

Protocols and materials databases

DNASUi8829.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8829.
KEGGihsa:8829.

Organism-specific databases

CTDi8829.
PharmGKBiPA31783.

Phylogenomic databases

eggNOGiENOG410IE8T. Eukaryota.
ENOG410YRBE. LUCA.
HOVERGENiHBG000502.
KOiK06724.

Miscellaneous databases

GenomeRNAii8829.

Gene expression databases

GenevisibleiQ68DN3. HS.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
2.60.120.290. 2 hits.
InterProiIPR013320. ConA-like_dom.
IPR000859. CUB_dom.
IPR000421. FA58C.
IPR008979. Galactose-bd-like.
IPR000998. MAM_dom.
IPR014648. Neuropilin.
IPR022579. Neuropilin_C.
IPR027146. NRP1.
[Graphical view]
PANTHERiPTHR10127:SF654. PTHR10127:SF654. 1 hit.
PfamiPF00431. CUB. 2 hits.
PF11980. DUF3481. 1 hit.
PF00754. F5_F8_type_C. 2 hits.
PF00629. MAM. 1 hit.
[Graphical view]
PIRSFiPIRSF036960. Neuropilin. 1 hit.
PRINTSiPR00020. MAMDOMAIN.
SMARTiSM00042. CUB. 2 hits.
SM00231. FA58C. 2 hits.
SM00137. MAM. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 2 hits.
SSF49854. SSF49854. 2 hits.
SSF49899. SSF49899. 1 hit.
PROSITEiPS01180. CUB. 2 hits.
PS01285. FA58C_1. 2 hits.
PS01286. FA58C_2. 2 hits.
PS50022. FA58C_3. 2 hits.
PS00740. MAM_1. 1 hit.
PS50060. MAM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Fetal kidneyImported.

Entry informationi

Entry nameiQ68DN3_HUMAN
AccessioniPrimary (citable) accession number: Q68DN3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: June 8, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.