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Q68D42

- TM215_HUMAN

UniProt

Q68D42 - TM215_HUMAN

Protein

Transmembrane protein 215

Gene

TMEM215

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (11 Oct 2004)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transmembrane protein 215
    Gene namesi
    Name:TMEM215
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:33816. TMEM215.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162406544.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 235235Transmembrane protein 215PRO_0000319324Add
    BLAST

    Proteomic databases

    PaxDbiQ68D42.
    PRIDEiQ68D42.

    PTM databases

    PhosphoSiteiQ68D42.

    Expressioni

    Gene expression databases

    BgeeiQ68D42.
    CleanExiHS_TMEM215.
    GenevestigatoriQ68D42.

    Organism-specific databases

    HPAiHPA052804.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68D42.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei12 – 3221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei40 – 6021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG42103.
    HOGENOMiHOG000082517.
    HOVERGENiHBG095177.
    InParanoidiQ68D42.
    OMAiCCYINQS.
    OrthoDBiEOG76X612.
    PhylomeDBiQ68D42.
    TreeFamiTF335695.

    Sequencei

    Sequence statusi: Complete.

    Q68D42-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRPDDINPRT GLVVALVSVF LVFGFMFTVS GMKGETLGNI PLLAIGPAIC    50
    LPGIAAIALA RKTEGCTKWP ENELLWVRKL PCFRKPKDKE VVELLRTPSD 100
    LESGKGSSDE LAKKAGLRGK PPPQSQGEVS VASSINSPTP TEEGECQSLV 150
    QNGHQEETSR YLDGYCPSGS SLTYSALDVK CSARDRSECP EPEDSIFFVP 200
    QDSIIVCSYK QNSPYDRYCC YINQIQGRWD HETIV 235
    Length:235
    Mass (Da):25,806
    Last modified:October 11, 2004 - v1
    Checksum:iB8381021EBBBB0F6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti69 – 691W → R in BAC86126. (PubMed:14702039)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK125320 mRNA. Translation: BAC86126.1.
    BX647550 mRNA. Translation: CAH56136.1.
    CR749589 mRNA. Translation: CAH18388.1.
    CH471071 Genomic DNA. Translation: EAW58539.1.
    CCDSiCCDS6530.1.
    RefSeqiNP_997723.2. NM_212558.2.
    UniGeneiHs.522063.

    Genome annotation databases

    EnsembliENST00000342743; ENSP00000345468; ENSG00000188133.
    GeneIDi401498.
    KEGGihsa:401498.
    UCSCiuc003zri.4. human.

    Polymorphism databases

    DMDMi74748275.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK125320 mRNA. Translation: BAC86126.1 .
    BX647550 mRNA. Translation: CAH56136.1 .
    CR749589 mRNA. Translation: CAH18388.1 .
    CH471071 Genomic DNA. Translation: EAW58539.1 .
    CCDSi CCDS6530.1.
    RefSeqi NP_997723.2. NM_212558.2.
    UniGenei Hs.522063.

    3D structure databases

    ProteinModelPortali Q68D42.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q68D42.

    Polymorphism databases

    DMDMi 74748275.

    Proteomic databases

    PaxDbi Q68D42.
    PRIDEi Q68D42.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000342743 ; ENSP00000345468 ; ENSG00000188133 .
    GeneIDi 401498.
    KEGGi hsa:401498.
    UCSCi uc003zri.4. human.

    Organism-specific databases

    CTDi 401498.
    GeneCardsi GC09P032783.
    H-InvDB HIX0025727.
    HGNCi HGNC:33816. TMEM215.
    HPAi HPA052804.
    neXtProti NX_Q68D42.
    PharmGKBi PA162406544.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG42103.
    HOGENOMi HOG000082517.
    HOVERGENi HBG095177.
    InParanoidi Q68D42.
    OMAi CCYINQS.
    OrthoDBi EOG76X612.
    PhylomeDBi Q68D42.
    TreeFami TF335695.

    Miscellaneous databases

    GenomeRNAii 401498.
    NextBioi 106912.
    PROi Q68D42.

    Gene expression databases

    Bgeei Q68D42.
    CleanExi HS_TMEM215.
    Genevestigatori Q68D42.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Teratocarcinoma.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Retina.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiTM215_HUMAN
    AccessioniPrimary (citable) accession number: Q68D42
    Secondary accession number(s): Q6ZUU2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM

    External Data

    Dasty 3