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Protein

Transmembrane protein 215

Gene

TMEM215

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 215
Gene namesi
Name:TMEM215
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:33816. TMEM215.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3221HelicalSequence AnalysisAdd
BLAST
Transmembranei40 – 6021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162406544.

Polymorphism and mutation databases

BioMutaiTMEM215.
DMDMi74748275.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Transmembrane protein 215PRO_0000319324Add
BLAST

Proteomic databases

PaxDbiQ68D42.
PRIDEiQ68D42.

PTM databases

PhosphoSiteiQ68D42.

Expressioni

Gene expression databases

BgeeiQ68D42.
CleanExiHS_TMEM215.

Organism-specific databases

HPAiHPA052804.

Structurei

3D structure databases

ProteinModelPortaliQ68D42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG42103.
GeneTreeiENSGT00390000006684.
HOGENOMiHOG000082517.
HOVERGENiHBG095177.
InParanoidiQ68D42.
OMAiCCYINQS.
OrthoDBiEOG76X612.
PhylomeDBiQ68D42.
TreeFamiTF335695.

Sequencei

Sequence statusi: Complete.

Q68D42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPDDINPRT GLVVALVSVF LVFGFMFTVS GMKGETLGNI PLLAIGPAIC
60 70 80 90 100
LPGIAAIALA RKTEGCTKWP ENELLWVRKL PCFRKPKDKE VVELLRTPSD
110 120 130 140 150
LESGKGSSDE LAKKAGLRGK PPPQSQGEVS VASSINSPTP TEEGECQSLV
160 170 180 190 200
QNGHQEETSR YLDGYCPSGS SLTYSALDVK CSARDRSECP EPEDSIFFVP
210 220 230
QDSIIVCSYK QNSPYDRYCC YINQIQGRWD HETIV
Length:235
Mass (Da):25,806
Last modified:October 11, 2004 - v1
Checksum:iB8381021EBBBB0F6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti69 – 691W → R in BAC86126 (PubMed:14702039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125320 mRNA. Translation: BAC86126.1.
BX647550 mRNA. Translation: CAH56136.1.
CR749589 mRNA. Translation: CAH18388.1.
CH471071 Genomic DNA. Translation: EAW58539.1.
CCDSiCCDS6530.1.
RefSeqiNP_997723.2. NM_212558.2.
UniGeneiHs.522063.

Genome annotation databases

EnsembliENST00000342743; ENSP00000345468; ENSG00000188133.
GeneIDi401498.
KEGGihsa:401498.
UCSCiuc003zri.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125320 mRNA. Translation: BAC86126.1.
BX647550 mRNA. Translation: CAH56136.1.
CR749589 mRNA. Translation: CAH18388.1.
CH471071 Genomic DNA. Translation: EAW58539.1.
CCDSiCCDS6530.1.
RefSeqiNP_997723.2. NM_212558.2.
UniGeneiHs.522063.

3D structure databases

ProteinModelPortaliQ68D42.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ68D42.

Polymorphism and mutation databases

BioMutaiTMEM215.
DMDMi74748275.

Proteomic databases

PaxDbiQ68D42.
PRIDEiQ68D42.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000342743; ENSP00000345468; ENSG00000188133.
GeneIDi401498.
KEGGihsa:401498.
UCSCiuc003zri.4. human.

Organism-specific databases

CTDi401498.
GeneCardsiGC09P032783.
H-InvDBHIX0025727.
HGNCiHGNC:33816. TMEM215.
HPAiHPA052804.
neXtProtiNX_Q68D42.
PharmGKBiPA162406544.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG42103.
GeneTreeiENSGT00390000006684.
HOGENOMiHOG000082517.
HOVERGENiHBG095177.
InParanoidiQ68D42.
OMAiCCYINQS.
OrthoDBiEOG76X612.
PhylomeDBiQ68D42.
TreeFamiTF335695.

Miscellaneous databases

GenomeRNAii401498.
NextBioi106912.
PROiQ68D42.

Gene expression databases

BgeeiQ68D42.
CleanExiHS_TMEM215.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Teratocarcinoma.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Retina.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiTM215_HUMAN
AccessioniPrimary (citable) accession number: Q68D42
Secondary accession number(s): Q6ZUU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 11, 2004
Last modified: June 24, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.