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Q68D42

- TM215_HUMAN

UniProt

Q68D42 - TM215_HUMAN

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Protein

Transmembrane protein 215

Gene

TMEM215

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 215
Gene namesi
Name:TMEM215
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:33816. TMEM215.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3221HelicalSequence AnalysisAdd
BLAST
Transmembranei40 – 6021HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162406544.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 235235Transmembrane protein 215PRO_0000319324Add
BLAST

Proteomic databases

PaxDbiQ68D42.
PRIDEiQ68D42.

PTM databases

PhosphoSiteiQ68D42.

Expressioni

Gene expression databases

BgeeiQ68D42.
CleanExiHS_TMEM215.
GenevestigatoriQ68D42.

Organism-specific databases

HPAiHPA052804.

Structurei

3D structure databases

ProteinModelPortaliQ68D42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG42103.
GeneTreeiENSGT00390000006684.
HOGENOMiHOG000082517.
HOVERGENiHBG095177.
InParanoidiQ68D42.
OMAiCCYINQS.
OrthoDBiEOG76X612.
PhylomeDBiQ68D42.
TreeFamiTF335695.

Sequencei

Sequence statusi: Complete.

Q68D42-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPDDINPRT GLVVALVSVF LVFGFMFTVS GMKGETLGNI PLLAIGPAIC
60 70 80 90 100
LPGIAAIALA RKTEGCTKWP ENELLWVRKL PCFRKPKDKE VVELLRTPSD
110 120 130 140 150
LESGKGSSDE LAKKAGLRGK PPPQSQGEVS VASSINSPTP TEEGECQSLV
160 170 180 190 200
QNGHQEETSR YLDGYCPSGS SLTYSALDVK CSARDRSECP EPEDSIFFVP
210 220 230
QDSIIVCSYK QNSPYDRYCC YINQIQGRWD HETIV
Length:235
Mass (Da):25,806
Last modified:October 11, 2004 - v1
Checksum:iB8381021EBBBB0F6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti69 – 691W → R in BAC86126. (PubMed:14702039)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125320 mRNA. Translation: BAC86126.1.
BX647550 mRNA. Translation: CAH56136.1.
CR749589 mRNA. Translation: CAH18388.1.
CH471071 Genomic DNA. Translation: EAW58539.1.
CCDSiCCDS6530.1.
RefSeqiNP_997723.2. NM_212558.2.
UniGeneiHs.522063.

Genome annotation databases

EnsembliENST00000342743; ENSP00000345468; ENSG00000188133.
GeneIDi401498.
KEGGihsa:401498.
UCSCiuc003zri.4. human.

Polymorphism databases

DMDMi74748275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125320 mRNA. Translation: BAC86126.1 .
BX647550 mRNA. Translation: CAH56136.1 .
CR749589 mRNA. Translation: CAH18388.1 .
CH471071 Genomic DNA. Translation: EAW58539.1 .
CCDSi CCDS6530.1.
RefSeqi NP_997723.2. NM_212558.2.
UniGenei Hs.522063.

3D structure databases

ProteinModelPortali Q68D42.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q68D42.

Polymorphism databases

DMDMi 74748275.

Proteomic databases

PaxDbi Q68D42.
PRIDEi Q68D42.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000342743 ; ENSP00000345468 ; ENSG00000188133 .
GeneIDi 401498.
KEGGi hsa:401498.
UCSCi uc003zri.4. human.

Organism-specific databases

CTDi 401498.
GeneCardsi GC09P032783.
H-InvDB HIX0025727.
HGNCi HGNC:33816. TMEM215.
HPAi HPA052804.
neXtProti NX_Q68D42.
PharmGKBi PA162406544.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG42103.
GeneTreei ENSGT00390000006684.
HOGENOMi HOG000082517.
HOVERGENi HBG095177.
InParanoidi Q68D42.
OMAi CCYINQS.
OrthoDBi EOG76X612.
PhylomeDBi Q68D42.
TreeFami TF335695.

Miscellaneous databases

GenomeRNAii 401498.
NextBioi 106912.
PROi Q68D42.

Gene expression databases

Bgeei Q68D42.
CleanExi HS_TMEM215.
Genevestigatori Q68D42.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Teratocarcinoma.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Retina.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiTM215_HUMAN
AccessioniPrimary (citable) accession number: Q68D42
Secondary accession number(s): Q6ZUU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 11, 2004
Last modified: October 29, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM

External Data

Dasty 3