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Q68CP9

- ARID2_HUMAN

UniProt

Q68CP9 - ARID2_HUMAN

Protein

AT-rich interactive domain-containing protein 2

Gene

ARID2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 107 (01 Oct 2014)
      Sequence version 2 (30 Aug 2005)
      Previous versions | rss
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    Functioni

    Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.1 Publication

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi524 – 60380RFX-type winged-helixPROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri1632 – 165726C2H2-typeAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: GDB
    2. metal ion binding Source: UniProtKB-KW
    3. protein binding Source: IntAct

    GO - Biological processi

    1. chromatin modification Source: UniProtKB-KW
    2. nucleosome disassembly Source: BHF-UCL
    3. regulation of transcription, DNA-templated Source: UniProtKB-KW
    4. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AT-rich interactive domain-containing protein 2
    Short name:
    ARID domain-containing protein 2
    Alternative name(s):
    BRG1-associated factor 200
    Short name:
    BAF200
    Zinc finger protein with activation potential
    Zipzap/p200
    Gene namesi
    Name:ARID2
    Synonyms:KIAA1557
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 12

    Organism-specific databases

    HGNCiHGNC:18037. ARID2.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134916396.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 18351834AT-rich interactive domain-containing protein 2PRO_0000200577Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanine1 Publication
    Modified residuei631 – 6311Phosphoserine1 Publication
    Modified residuei635 – 6351Phosphoserine2 Publications
    Modified residuei653 – 6531Phosphothreonine1 Publication
    Modified residuei689 – 6891Phosphoserine2 Publications
    Modified residuei692 – 6921Phosphothreonine1 Publication
    Modified residuei1496 – 14961Phosphoserine2 Publications

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ68CP9.
    PaxDbiQ68CP9.
    PRIDEiQ68CP9.

    PTM databases

    PhosphoSiteiQ68CP9.

    Miscellaneous databases

    PMAP-CutDBQ68CP9.

    Expressioni

    Tissue specificityi

    Highly expressed in heart and testis.1 Publication

    Developmental stagei

    Up-regulated in adult heart (at protein level).1 Publication

    Gene expression databases

    ArrayExpressiQ68CP9.
    BgeeiQ68CP9.
    GenevestigatoriQ68CP9.

    Organism-specific databases

    HPAiHPA052256.

    Interactioni

    Subunit structurei

    Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin. Interacts with SRF. Forms complexes with SRF and SRF cofactors MYOCD, NKX2-5 and SRFBP1.2 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    PBRM1Q86U865EBI-637818,EBI-637807
    SMARCA4P515326EBI-637818,EBI-302489
    SMARCB1Q128243EBI-637818,EBI-358419
    SMARCE1Q969G34EBI-637818,EBI-455078

    Protein-protein interaction databases

    BioGridi128219. 18 interactions.
    DIPiDIP-33391N.
    IntActiQ68CP9. 11 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ68CP9.
    SMRiQ68CP9. Positions 11-101.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini13 – 10593ARIDPROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi313 – 3175LXXLL

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi793 – 1128336Gln-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 ARID domain.PROSITE-ProRule annotation
    Contains 1 C2H2-type zinc finger.Curated
    Contains 1 RFX-type winged-helix DNA-binding domain.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri1632 – 165726C2H2-typeAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG311317.
    HOVERGENiHBG068777.
    InParanoidiQ68CP9.
    KOiK11765.
    OMAiLKQYYLR.
    OrthoDBiEOG75QR38.
    PhylomeDBiQ68CP9.
    TreeFamiTF106406.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    1.10.150.60. 1 hit.
    InterProiIPR001606. ARID/BRIGHT_DNA-bd.
    IPR016024. ARM-type_fold.
    IPR003150. DNA-bd_RFX.
    IPR011991. WHTH_DNA-bd_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    [Graphical view]
    PfamiPF01388. ARID. 1 hit.
    PF02257. RFX_DNA_binding. 1 hit.
    [Graphical view]
    SMARTiSM00501. BRIGHT. 1 hit.
    SM00355. ZnF_C2H2. 2 hits.
    [Graphical view]
    SUPFAMiSSF46774. SSF46774. 1 hit.
    SSF48371. SSF48371. 2 hits.
    PROSITEiPS51011. ARID. 1 hit.
    PS51526. RFX_DBD. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q68CP9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MANSTGKAPP DERRKGLAFL DELRQFHHSR GSPFKKIPAV GGKELDLHGL     50
    YTRVTTLGGF AKVSEKNQWG EIVEEFNFPR SCSNAAFALK QYYLRYLEKY 100
    EKVHHFGEDD DEVPPGNPKP QLPIGAIPSS YNYQQHSVSD YLRQSYGLSM 150
    DFNSPNDYNK LVLSLLSGLP NEVDFAINVC TLLSNESKHV MQLEKDPKII 200
    TLLLANAGVF DDTLGSFSTV FGEEWKEKTD RDFVKFWKDI VDDNEVRDLI 250
    SDRNKSHEGT SGEWIWESLF HPPRKLGIND IEGQRVLQIA VILRNLSFEE 300
    GNVKLLAANR TCLRFLLLSA HSHFISLRQL GLDTLGNIAA ELLLDPVDFK 350
    TTHLMFHTVT KCLMSRDRFL KMRGMEILGN LCKAEDNGVL ICEYVDQDSY 400
    REIICHLTLP DVLLVISTLE VLYMLTEMGD VACTKIAKVE KSIDMLVCLV 450
    SMDIQMFGPD ALAAVKLIEH PSSSHQMLSE IRPQAIEQVQ TQTHVASAPA 500
    SRAVVAQHVA PPPGIVEIDS EKFACQWLNA HFEVNPDCSV SRAEMYSEYL 550
    STCSKLARGG ILTSTGFYKC LRTVFPNHTV KRVEDSSSNG QAHIHVVGVK 600
    RRAIPLPIQM YYQQQPVSTS VVRVDSVPDV SPAPSPAGIP HGSQTIGNHF 650
    QRTPVANQSS NLTATQMSFP VQGVHTVAQT VSRIPQNPSP HTHQQQNAPV 700
    TVIQSKAPIP CEVVKATVIQ NSIPQTGVPV SIAVGGGPPQ SSVVQNHSTG 750
    PQPVTVVNSQ TLLHHPSVIP QQSPLHTVVP GQIPSGTPVT VIQQAVPQSH 800
    MFGRVQNIPA CTSTVSQGQQ LITTSPQPVQ TSSQQTSAGS QSQDTVIIAP 850
    PQYVTTSASN IVSATSVQNF QVATGQMVTI AGVPSPQASR VGFQNIAPKP 900
    LPSQQVSSTV VQQPIQQPQQ PTQQSVVIVS QPAQQGQTYA PAIHQIVLAN 950
    PAALPAGQTV QLTGQPNITP SSSPSPVPAT NNQVPTAMSS SSTPQSQGPP 1000
    PTVSQMLSVK RQQQQQHSPA PPPQQVQVQV QQPQQVQMQV QPQQSNAGVG 1050
    QPASGESSLI KQLLLPKRGP STPGGKLILP APQIPPPNNA RAPSPQVVYQ 1100
    VASNQAAGFG VQGQTPAQQL LVGQQNVQLV PSAMPPSGGV QTVPISNLQI 1150
    LPGPLISNSP ATIFQGTSGN QVTITVVPNT SFAPATVSQG NATQLIAPAG 1200
    ITMSGTQTGV GLPVQTLPAT QASPAGQSSC TTATPPFKGD KIICQKEEEA 1250
    KEATGLHVHE RKIEVMENPS CRRGATNTSN GDTKENEMHV GSLLNGRKYS 1300
    DSSLPPSNSG KIQSETNQCS LISNGPSLEL GENGASGKQN SEQIDMQDIK 1350
    SDLRKPLVNG ICDFDKGDGS HLSKNIPNHK TSNHVGNGEI SPMEPQGTLD 1400
    ITQQDTAKGD QLERISNGPV LTLGGSSVSS IQEASNAATQ QFSGTDLLNG 1450
    PLASSLNSDV PQQRPSVVVS PHSTTSVIQG HQIIAVPDSG SKVSHSPALS 1500
    SDVRSTNGTA ECKTVKRPAE DTDRETVAGI PNKVGVRIVT ISDPNNAGCS 1550
    ATMVAVPAGA DPSTVAKVAI ESAVQQKQQH PPTYVQNVVP QNTPMPPSPA 1600
    VQVQGQPNSS QPSPFSGSSQ PGDPMRKPGQ NFMCLWQSCK KWFQTPSQVF 1650
    YHAATEHGGK DVYPGQCLWE GCEPFQRQRF SFITHLQDKH CSKDALLAGL 1700
    KQDEPGQAGS QKSSTKQPTV GGTSSTPRAQ KAIVNHPSAA LMALRRGSRN 1750
    LVFRDFTDEK EGPITKHIRL TAALILKNIG KYSECGRRLL KRHENNLSVL 1800
    AISNMEASST LAKCLYELNF TVQSKEQEKD SEMLQ 1835
    Length:1,835
    Mass (Da):197,391
    Last modified:August 30, 2005 - v2
    Checksum:iF540A029FA2264D4
    GO
    Isoform 2 (identifier: Q68CP9-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1784-1835: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,783
    Mass (Da):191,422
    Checksum:iDD2BB28AF96DC860
    GO

    Sequence cautioni

    The sequence AAU20329.2 differs from that shown. Reason: Differs from position 1094 onward for unknown reason.
    The sequence BAC87171.1 differs from that shown. Reason: Unlikely isoform. Cloning artifact.
    The sequence BAB55320.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti169 – 1691L → P in CAH18689. (PubMed:17974005)Curated
    Sequence conflicti217 – 2171F → L in CAD91164. (PubMed:17974005)Curated
    Sequence conflicti665 – 6651T → I in CAD91164. (PubMed:17974005)Curated
    Sequence conflicti801 – 8011M → T in AAZ74794. (PubMed:16782067)Curated
    Sequence conflicti825 – 8251S → P in CAH18689. (PubMed:17974005)Curated
    Sequence conflicti906 – 9061V → F in CAD91164. (PubMed:17974005)Curated
    Sequence conflicti956 – 9561A → V in CAD91164. (PubMed:17974005)Curated
    Sequence conflicti988 – 9881M → T in CAH18689. (PubMed:17974005)Curated
    Sequence conflicti989 – 9891S → P in CAD97878. (PubMed:17974005)Curated
    Sequence conflicti1035 – 10351Q → R in BAB55320. (PubMed:14702039)Curated
    Sequence conflicti1062 – 10621Q → R in CAH18689. (PubMed:17974005)Curated
    Sequence conflicti1204 – 12041S → G in CAD97878. (PubMed:17974005)Curated
    Sequence conflicti1292 – 12921S → N in CAD97878. (PubMed:17974005)Curated
    Sequence conflicti1460 – 14601V → A in CAD97878. (PubMed:17974005)Curated
    Sequence conflicti1543 – 15431D → G in CAD91164. (PubMed:17974005)Curated
    Sequence conflicti1543 – 15431D → N in BAC87171. (PubMed:14702039)Curated
    Sequence conflicti1647 – 16471S → P in CAD97878. (PubMed:17974005)Curated
    Sequence conflicti1700 – 17001L → S in CAD91164. (PubMed:17974005)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1784 – 183552Missing in isoform 2. 1 PublicationVSP_015230Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ096628 mRNA. Translation: AAZ74794.1.
    AY727870 mRNA. Translation: AAU20329.2. Different termination.
    AL832200 mRNA. Translation: CAD91164.1.
    BX537879 mRNA. Translation: CAD97878.1.
    CR749833 mRNA. Translation: CAH18689.1.
    AK027718 mRNA. Translation: BAB55320.1. Different initiation.
    AK127872 mRNA. Translation: BAC87171.1. Sequence problems.
    BC090062 mRNA. Translation: AAH90062.1.
    AB046777 mRNA. Translation: BAB13383.1.
    CCDSiCCDS31783.1. [Q68CP9-1]
    RefSeqiNP_689854.2. NM_152641.2. [Q68CP9-1]
    UniGeneiHs.317304.

    Genome annotation databases

    EnsembliENST00000334344; ENSP00000335044; ENSG00000189079. [Q68CP9-1]
    GeneIDi196528.
    KEGGihsa:196528.
    UCSCiuc001ror.3. human. [Q68CP9-1]

    Polymorphism databases

    DMDMi73921721.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DQ096628 mRNA. Translation: AAZ74794.1 .
    AY727870 mRNA. Translation: AAU20329.2 . Different termination.
    AL832200 mRNA. Translation: CAD91164.1 .
    BX537879 mRNA. Translation: CAD97878.1 .
    CR749833 mRNA. Translation: CAH18689.1 .
    AK027718 mRNA. Translation: BAB55320.1 . Different initiation.
    AK127872 mRNA. Translation: BAC87171.1 . Sequence problems.
    BC090062 mRNA. Translation: AAH90062.1 .
    AB046777 mRNA. Translation: BAB13383.1 .
    CCDSi CCDS31783.1. [Q68CP9-1 ]
    RefSeqi NP_689854.2. NM_152641.2. [Q68CP9-1 ]
    UniGenei Hs.317304.

    3D structure databases

    ProteinModelPortali Q68CP9.
    SMRi Q68CP9. Positions 11-101.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 128219. 18 interactions.
    DIPi DIP-33391N.
    IntActi Q68CP9. 11 interactions.

    PTM databases

    PhosphoSitei Q68CP9.

    Polymorphism databases

    DMDMi 73921721.

    Proteomic databases

    MaxQBi Q68CP9.
    PaxDbi Q68CP9.
    PRIDEi Q68CP9.

    Protocols and materials databases

    DNASUi 196528.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000334344 ; ENSP00000335044 ; ENSG00000189079 . [Q68CP9-1 ]
    GeneIDi 196528.
    KEGGi hsa:196528.
    UCSCi uc001ror.3. human. [Q68CP9-1 ]

    Organism-specific databases

    CTDi 196528.
    GeneCardsi GC12P046123.
    HGNCi HGNC:18037. ARID2.
    HPAi HPA052256.
    MIMi 609539. gene.
    neXtProti NX_Q68CP9.
    PharmGKBi PA134916396.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG311317.
    HOVERGENi HBG068777.
    InParanoidi Q68CP9.
    KOi K11765.
    OMAi LKQYYLR.
    OrthoDBi EOG75QR38.
    PhylomeDBi Q68CP9.
    TreeFami TF106406.

    Miscellaneous databases

    GeneWikii ARID2.
    GenomeRNAii 196528.
    NextBioi 89525.
    PMAP-CutDB Q68CP9.
    PROi Q68CP9.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q68CP9.
    Bgeei Q68CP9.
    Genevestigatori Q68CP9.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    1.10.150.60. 1 hit.
    InterProi IPR001606. ARID/BRIGHT_DNA-bd.
    IPR016024. ARM-type_fold.
    IPR003150. DNA-bd_RFX.
    IPR011991. WHTH_DNA-bd_dom.
    IPR007087. Znf_C2H2.
    IPR015880. Znf_C2H2-like.
    [Graphical view ]
    Pfami PF01388. ARID. 1 hit.
    PF02257. RFX_DNA_binding. 1 hit.
    [Graphical view ]
    SMARTi SM00501. BRIGHT. 1 hit.
    SM00355. ZnF_C2H2. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46774. SSF46774. 1 hit.
    SSF48371. SSF48371. 2 hits.
    PROSITEi PS51011. ARID. 1 hit.
    PS51526. RFX_DBD. 1 hit.
    PS00028. ZINC_FINGER_C2H2_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation."
      Zhang X., Azhar G., Zhong Y., Wei J.Y.
      Biochem. Biophys. Res. Commun. 346:794-801(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH SRF, SUBUNIT, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
      Tissue: Heart.
    2. "DNA-binding properties of ARID family proteins."
      Patsialou A., Wilsker D., Moran E.
      Nucleic Acids Res. 33:66-80(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1093, DNA-BINDING.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 28-1835 (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 150-1835 (ISOFORM 1).
      Tissue: Liver.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 950-1835 (ISOFORM 1).
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 976-1835 (ISOFORM 1).
      Tissue: Testis.
    6. "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O.
      DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1030-1835 (ISOFORM 1).
      Tissue: Brain.
    7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-631; SER-635; THR-653; SER-689; THR-692 AND SER-1496, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-635; SER-689 AND SER-1496, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
    11. "Recent advances in understanding chromatin remodeling by SWI/SNF complexes."
      Martens J.A., Winston F.
      Curr. Opin. Genet. Dev. 13:136-142(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: REVIEW ON SWI/SNF CHROMATIN REMODELING COMPLEXES.
    12. "PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes."
      Yan Z., Cui K., Murray D.M., Ling C., Xue Y., Gerstein A., Parsons R., Zhao K., Wang W.
      Genes Dev. 19:1662-1667(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE PBAF COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.

    Entry informationi

    Entry nameiARID2_HUMAN
    AccessioniPrimary (citable) accession number: Q68CP9
    Secondary accession number(s): Q15KG9
    , Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: August 30, 2005
    Last modified: October 1, 2014
    This is version 107 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 12
      Human chromosome 12: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3