Q68CP9 (ARID2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
AT-rich interactive domain-containing protein 2
Short name=ARID domain-containing protein 2

Alternative name(s):
BRG1-associated factor 200
Short name=BAF200
Zinc finger protein with activation potential
Zipzap/p200

Gene names

Name:	ARID2
Synonyms:	KIAA1557

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1835 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes. Ref.1
Subunit structure	Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF250B and actin. Interacts with SRF. Forms complexes with SRF and SRF cofactors MYOCD, NKX2-5 and SRFBP1. Ref.1 Ref.11
Subcellular location	Nucleus.
Tissue specificity	Highly expressed in heart and testis. Ref.1
Developmental stage	Up-regulated in adult heart (at protein level). Ref.1
Sequence similarities	Contains 1 ARID domain. Contains 1 C2H2-type zinc finger. Contains 1 RFX-type winged-helix DNA-binding domain.
Sequence caution	The sequence AAU20329.2 differs from that shown. Reason: Differs from position 1094 onward for unknown reason. The sequence BAB55320.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence BAC87171.1 differs from that shown. Reason: Unlikely isoform. Cloning artifact.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
Molecular function	Chromatin regulator
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chromatin modification Inferred from electronic annotation. Source: UniProtKB-KW nucleosome disassembly Inferred from direct assay PubMed 8895581. Source: BHF-UCL regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from direct assay Ref.2. Source: GDB zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
PBRM1	Q86U86	5	EBI-637818,EBI-637807
SMARCA4	P51532	6	EBI-637818,EBI-302489
SMARCB1	Q12824	3	EBI-637818,EBI-358419
SMARCE1	Q969G3	4	EBI-637818,EBI-455078

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q68CP9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q68CP9-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1784-1835: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1835	1835	AT-rich interactive domain-containing protein 2		PRO_0000200577
Regions
	Domain	13 – 105	93	ARID
	DNA binding	524 – 603	80	RFX-type winged-helix Ref.2
	Zinc finger	1632 – 1657	26	C2H2-type
	Motif	313 – 317	5	LXXLL
	Compositional bias	793 – 1128	336	Gln-rich
Amino acid modifications
	Modified residue	631	1	Phosphoserine Ref.7
	Modified residue	635	1	Phosphoserine Ref.7 Ref.8
	Modified residue	653	1	Phosphothreonine Ref.7
	Modified residue	689	1	Phosphoserine Ref.7 Ref.8
	Modified residue	692	1	Phosphothreonine Ref.7
	Modified residue	1496	1	Phosphoserine Ref.7 Ref.8
Natural variations
	Alternative sequence	1784 – 1835	52	Missing in isoform 2.		VSP_015230
Experimental info
	Sequence conflict	169	1	L → P in CAH18689. Ref.3
	Sequence conflict	217	1	F → L in CAD91164. Ref.3
	Sequence conflict	665	1	T → I in CAD91164. Ref.3
	Sequence conflict	801	1	M → T in AAZ74794. Ref.1
	Sequence conflict	825	1	S → P in CAH18689. Ref.3
	Sequence conflict	906	1	V → F in CAD91164. Ref.3
	Sequence conflict	956	1	A → V in CAD91164. Ref.3
	Sequence conflict	988	1	M → T in CAH18689. Ref.3
	Sequence conflict	989	1	S → P in CAD97878. Ref.3
	Sequence conflict	1035	1	Q → R in BAB55320. Ref.4
	Sequence conflict	1062	1	Q → R in CAH18689. Ref.3
	Sequence conflict	1204	1	S → G in CAD97878. Ref.3
	Sequence conflict	1292	1	S → N in CAD97878. Ref.3
	Sequence conflict	1460	1	V → A in CAD97878. Ref.3
	Sequence conflict	1543	1	D → G in CAD91164. Ref.3
	Sequence conflict	1543	1	D → N in BAC87171. Ref.4
	Sequence conflict	1647	1	S → P in CAD97878. Ref.3
	Sequence conflict	1700	1	L → S in CAD91164. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified August 30, 2005. Version 2. Checksum: F540A029FA2264D4	FASTA	1,835	197,391
	10 20 30 40 50 60 MANSTGKAPP DERRKGLAFL DELRQFHHSR GSPFKKIPAV GGKELDLHGL YTRVTTLGGF 70 80 90 100 110 120 AKVSEKNQWG EIVEEFNFPR SCSNAAFALK QYYLRYLEKY EKVHHFGEDD DEVPPGNPKP 130 140 150 160 170 180 QLPIGAIPSS YNYQQHSVSD YLRQSYGLSM DFNSPNDYNK LVLSLLSGLP NEVDFAINVC 190 200 210 220 230 240 TLLSNESKHV MQLEKDPKII TLLLANAGVF DDTLGSFSTV FGEEWKEKTD RDFVKFWKDI 250 260 270 280 290 300 VDDNEVRDLI SDRNKSHEGT SGEWIWESLF HPPRKLGIND IEGQRVLQIA VILRNLSFEE 310 320 330 340 350 360 GNVKLLAANR TCLRFLLLSA HSHFISLRQL GLDTLGNIAA ELLLDPVDFK TTHLMFHTVT 370 380 390 400 410 420 KCLMSRDRFL KMRGMEILGN LCKAEDNGVL ICEYVDQDSY REIICHLTLP DVLLVISTLE 430 440 450 460 470 480 VLYMLTEMGD VACTKIAKVE KSIDMLVCLV SMDIQMFGPD ALAAVKLIEH PSSSHQMLSE 490 500 510 520 530 540 IRPQAIEQVQ TQTHVASAPA SRAVVAQHVA PPPGIVEIDS EKFACQWLNA HFEVNPDCSV 550 560 570 580 590 600 SRAEMYSEYL STCSKLARGG ILTSTGFYKC LRTVFPNHTV KRVEDSSSNG QAHIHVVGVK 610 620 630 640 650 660 RRAIPLPIQM YYQQQPVSTS VVRVDSVPDV SPAPSPAGIP HGSQTIGNHF QRTPVANQSS 670 680 690 700 710 720 NLTATQMSFP VQGVHTVAQT VSRIPQNPSP HTHQQQNAPV TVIQSKAPIP CEVVKATVIQ 730 740 750 760 770 780 NSIPQTGVPV SIAVGGGPPQ SSVVQNHSTG PQPVTVVNSQ TLLHHPSVIP QQSPLHTVVP 790 800 810 820 830 840 GQIPSGTPVT VIQQAVPQSH MFGRVQNIPA CTSTVSQGQQ LITTSPQPVQ TSSQQTSAGS 850 860 870 880 890 900 QSQDTVIIAP PQYVTTSASN IVSATSVQNF QVATGQMVTI AGVPSPQASR VGFQNIAPKP 910 920 930 940 950 960 LPSQQVSSTV VQQPIQQPQQ PTQQSVVIVS QPAQQGQTYA PAIHQIVLAN PAALPAGQTV 970 980 990 1000 1010 1020 QLTGQPNITP SSSPSPVPAT NNQVPTAMSS SSTPQSQGPP PTVSQMLSVK RQQQQQHSPA 1030 1040 1050 1060 1070 1080 PPPQQVQVQV QQPQQVQMQV QPQQSNAGVG QPASGESSLI KQLLLPKRGP STPGGKLILP 1090 1100 1110 1120 1130 1140 APQIPPPNNA RAPSPQVVYQ VASNQAAGFG VQGQTPAQQL LVGQQNVQLV PSAMPPSGGV 1150 1160 1170 1180 1190 1200 QTVPISNLQI LPGPLISNSP ATIFQGTSGN QVTITVVPNT SFAPATVSQG NATQLIAPAG 1210 1220 1230 1240 1250 1260 ITMSGTQTGV GLPVQTLPAT QASPAGQSSC TTATPPFKGD KIICQKEEEA KEATGLHVHE 1270 1280 1290 1300 1310 1320 RKIEVMENPS CRRGATNTSN GDTKENEMHV GSLLNGRKYS DSSLPPSNSG KIQSETNQCS 1330 1340 1350 1360 1370 1380 LISNGPSLEL GENGASGKQN SEQIDMQDIK SDLRKPLVNG ICDFDKGDGS HLSKNIPNHK 1390 1400 1410 1420 1430 1440 TSNHVGNGEI SPMEPQGTLD ITQQDTAKGD QLERISNGPV LTLGGSSVSS IQEASNAATQ 1450 1460 1470 1480 1490 1500 QFSGTDLLNG PLASSLNSDV PQQRPSVVVS PHSTTSVIQG HQIIAVPDSG SKVSHSPALS 1510 1520 1530 1540 1550 1560 SDVRSTNGTA ECKTVKRPAE DTDRETVAGI PNKVGVRIVT ISDPNNAGCS ATMVAVPAGA 1570 1580 1590 1600 1610 1620 DPSTVAKVAI ESAVQQKQQH PPTYVQNVVP QNTPMPPSPA VQVQGQPNSS QPSPFSGSSQ 1630 1640 1650 1660 1670 1680 PGDPMRKPGQ NFMCLWQSCK KWFQTPSQVF YHAATEHGGK DVYPGQCLWE GCEPFQRQRF 1690 1700 1710 1720 1730 1740 SFITHLQDKH CSKDALLAGL KQDEPGQAGS QKSSTKQPTV GGTSSTPRAQ KAIVNHPSAA 1750 1760 1770 1780 1790 1800 LMALRRGSRN LVFRDFTDEK EGPITKHIRL TAALILKNIG KYSECGRRLL KRHENNLSVL 1810 1820 1830 AISNMEASST LAKCLYELNF TVQSKEQEKD SEMLQ
	Isoform 2 [UniParc]. Checksum: DD2BB28AF96DC860	FASTA	1,783	191,422
	10 20 30 40 50 60 MANSTGKAPP DERRKGLAFL DELRQFHHSR GSPFKKIPAV GGKELDLHGL YTRVTTLGGF 70 80 90 100 110 120 AKVSEKNQWG EIVEEFNFPR SCSNAAFALK QYYLRYLEKY EKVHHFGEDD DEVPPGNPKP 130 140 150 160 170 180 QLPIGAIPSS YNYQQHSVSD YLRQSYGLSM DFNSPNDYNK LVLSLLSGLP NEVDFAINVC 190 200 210 220 230 240 TLLSNESKHV MQLEKDPKII TLLLANAGVF DDTLGSFSTV FGEEWKEKTD RDFVKFWKDI 250 260 270 280 290 300 VDDNEVRDLI SDRNKSHEGT SGEWIWESLF HPPRKLGIND IEGQRVLQIA VILRNLSFEE 310 320 330 340 350 360 GNVKLLAANR TCLRFLLLSA HSHFISLRQL GLDTLGNIAA ELLLDPVDFK TTHLMFHTVT 370 380 390 400 410 420 KCLMSRDRFL KMRGMEILGN LCKAEDNGVL ICEYVDQDSY REIICHLTLP DVLLVISTLE 430 440 450 460 470 480 VLYMLTEMGD VACTKIAKVE KSIDMLVCLV SMDIQMFGPD ALAAVKLIEH PSSSHQMLSE 490 500 510 520 530 540 IRPQAIEQVQ TQTHVASAPA SRAVVAQHVA PPPGIVEIDS EKFACQWLNA HFEVNPDCSV 550 560 570 580 590 600 SRAEMYSEYL STCSKLARGG ILTSTGFYKC LRTVFPNHTV KRVEDSSSNG QAHIHVVGVK 610 620 630 640 650 660 RRAIPLPIQM YYQQQPVSTS VVRVDSVPDV SPAPSPAGIP HGSQTIGNHF QRTPVANQSS 670 680 690 700 710 720 NLTATQMSFP VQGVHTVAQT VSRIPQNPSP HTHQQQNAPV TVIQSKAPIP CEVVKATVIQ 730 740 750 760 770 780 NSIPQTGVPV SIAVGGGPPQ SSVVQNHSTG PQPVTVVNSQ TLLHHPSVIP QQSPLHTVVP 790 800 810 820 830 840 GQIPSGTPVT VIQQAVPQSH MFGRVQNIPA CTSTVSQGQQ LITTSPQPVQ TSSQQTSAGS 850 860 870 880 890 900 QSQDTVIIAP PQYVTTSASN IVSATSVQNF QVATGQMVTI AGVPSPQASR VGFQNIAPKP 910 920 930 940 950 960 LPSQQVSSTV VQQPIQQPQQ PTQQSVVIVS QPAQQGQTYA PAIHQIVLAN PAALPAGQTV 970 980 990 1000 1010 1020 QLTGQPNITP SSSPSPVPAT NNQVPTAMSS SSTPQSQGPP PTVSQMLSVK RQQQQQHSPA 1030 1040 1050 1060 1070 1080 PPPQQVQVQV QQPQQVQMQV QPQQSNAGVG QPASGESSLI KQLLLPKRGP STPGGKLILP 1090 1100 1110 1120 1130 1140 APQIPPPNNA RAPSPQVVYQ VASNQAAGFG VQGQTPAQQL LVGQQNVQLV PSAMPPSGGV 1150 1160 1170 1180 1190 1200 QTVPISNLQI LPGPLISNSP ATIFQGTSGN QVTITVVPNT SFAPATVSQG NATQLIAPAG 1210 1220 1230 1240 1250 1260 ITMSGTQTGV GLPVQTLPAT QASPAGQSSC TTATPPFKGD KIICQKEEEA KEATGLHVHE 1270 1280 1290 1300 1310 1320 RKIEVMENPS CRRGATNTSN GDTKENEMHV GSLLNGRKYS DSSLPPSNSG KIQSETNQCS 1330 1340 1350 1360 1370 1380 LISNGPSLEL GENGASGKQN SEQIDMQDIK SDLRKPLVNG ICDFDKGDGS HLSKNIPNHK 1390 1400 1410 1420 1430 1440 TSNHVGNGEI SPMEPQGTLD ITQQDTAKGD QLERISNGPV LTLGGSSVSS IQEASNAATQ 1450 1460 1470 1480 1490 1500 QFSGTDLLNG PLASSLNSDV PQQRPSVVVS PHSTTSVIQG HQIIAVPDSG SKVSHSPALS 1510 1520 1530 1540 1550 1560 SDVRSTNGTA ECKTVKRPAE DTDRETVAGI PNKVGVRIVT ISDPNNAGCS ATMVAVPAGA 1570 1580 1590 1600 1610 1620 DPSTVAKVAI ESAVQQKQQH PPTYVQNVVP QNTPMPPSPA VQVQGQPNSS QPSPFSGSSQ 1630 1640 1650 1660 1670 1680 PGDPMRKPGQ NFMCLWQSCK KWFQTPSQVF YHAATEHGGK DVYPGQCLWE GCEPFQRQRF 1690 1700 1710 1720 1730 1740 SFITHLQDKH CSKDALLAGL KQDEPGQAGS QKSSTKQPTV GGTSSTPRAQ KAIVNHPSAA 1750 1760 1770 1780 LMALRRGSRN LVFRDFTDEK EGPITKHIRL TAALILKNIG KYS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation." Zhang X., Azhar G., Zhong Y., Wei J.Y. Biochem. Biophys. Res. Commun. 346:794-801(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH SRF, SUBUNIT, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE. Tissue: Heart.
[2]	"DNA-binding properties of ARID family proteins." Patsialou A., Wilsker D., Moran E. Nucleic Acids Res. 33:66-80(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1093, DNA-BINDING.
[3]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 28-1835 (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 150-1835 (ISOFORM 1). Tissue: Liver.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 950-1835 (ISOFORM 1).
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 976-1835 (ISOFORM 1). Tissue: Testis.
[6]	"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Nakayama M., Hirosawa M., Ohara O. DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1030-1835 (ISOFORM 1). Tissue: Brain.
[7]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-631; SER-635; THR-653; SER-689; THR-692 AND SER-1496, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-635; SER-689 AND SER-1496, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[9]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[10]	"Recent advances in understanding chromatin remodeling by SWI/SNF complexes." Martens J.A., Winston F. Curr. Opin. Genet. Dev. 13:136-142(2003) [PubMed] [Europe PMC] [Abstract] Cited for: REVIEW ON SWI/SNF CHROMATIN REMODELING COMPLEXES.
[11]	"PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes." Yan Z., Cui K., Murray D.M., Ling C., Xue Y., Gerstein A., Parsons R., Zhao K., Wang W. Genes Dev. 19:1662-1667(2005) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION IN THE PBAF COMPLEX, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DQ096628 mRNA. Translation: AAZ74794.1. AY727870 mRNA. Translation: AAU20329.2. Different termination. AL832200 mRNA. Translation: CAD91164.1. BX537879 mRNA. Translation: CAD97878.1. CR749833 mRNA. Translation: CAH18689.1. AK027718 mRNA. Translation: BAB55320.1. Different initiation. AK127872 mRNA. Translation: BAC87171.1. Sequence problems. BC090062 mRNA. Translation: AAH90062.1. AB046777 mRNA. Translation: BAB13383.1.
IPI	IPI00444237. IPI00470537. IPI00647133.
RefSeq	NP_689854.2. NM_152641.2.
UniGene	Hs.317304.
3D structure databases
ProteinModelPortal	Q68CP9.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-33391N.
IntAct	Q68CP9. 11 interactions.
PTM databases
PhosphoSite	Q68CP9.
Polymorphism databases
DMDM	73921721.
Proteomic databases
PaxDb	Q68CP9.
PRIDE	Q68CP9.
Protocols and materials databases
DNASU	196528.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000334344; ENSP00000335044; ENSG00000189079.
GeneID	196528.
KEGG	hsa:196528.
UCSC	uc001ror.3. human.
Organism-specific databases
CTD	196528.
GeneCards	GC12P046123.
HGNC	HGNC:18037. ARID2.
MIM	609539. gene.
neXtProt	NX_Q68CP9.
PharmGKB	PA134916396.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG311317.
HOVERGEN	HBG068777.
InParanoid	Q68CP9.
KO	K11765.
OMA	IQNSIPQ.
OrthoDB	EOG49KFPP.
Gene expression databases
ArrayExpress	Q68CP9.
Bgee	Q68CP9.
Genevestigator	Q68CP9.
Family and domain databases
Gene3D	1.10.10.10. 1 hit. 1.10.150.60. 1 hit.
InterPro	IPR001606. ARID/BRIGHT_DNA-bd. IPR003150. DNA-bd_RFX. IPR011991. WHTH_DNA-bd_dom. IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. [Graphical view]
Pfam	PF01388. ARID. 1 hit. PF02257. RFX_DNA_binding. 1 hit. [Graphical view]
SMART	SM00501. BRIGHT. 1 hit. SM00355. ZnF_C2H2. 2 hits. [Graphical view]
SUPFAM	SSF46774. ARID. 1 hit.
PROSITE	PS51011. ARID. 1 hit. PS51526. RFX_DBD. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. False negative. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	196528.
NextBio	89525.
PMAP-CutDB	Q68CP9.
SOURCE	Search...

Entry information

Entry name

ARID2_HUMAN

Accession

Primary (citable) accession number: Q68CP9
Secondary accession number(s): Q15KG9 , Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	August 30, 2005
Last modified:	May 1, 2013
This is version 96 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.