Unreviewed, UniProtKB/TrEMBL Q68A19 (Q68A19_HUMAN)

Names and origin

Protein names

Submitted name:
    Iroquois homeobox protein 2 EMBL BAD37140.1

Gene names

Name:

IRX2 EMBL BAD37140.1

Organism

Homo sapiens (Human) EMBL BAD37140.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location

NucleusBy similarity. RuleBase RU000682V4

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682V4
Domain	Homeobox RuleBase RU000682V4
Ligand	DNA-binding RuleBase RU000682V4
Gene Ontology (GO)
Biological process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q68A19-1 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 3B370608B5223C3C	FASTA	471	49,129
	10 20 30 40 50 60 MSYPQGYLYQ APGSLALYSC PAYGASALAA PRSEELARSA SGSAFSPYPG SAAFTAQAAT 70 80 90 100 110 120 GFGSPLQYSA DAAAAAAGFP SYMGAPYDAH TTGMTGAISY HPYGSAAYPY QLNDPAYRKN 130 140 150 160 170 180 ATRDATATLK AWLNEHRKNP YPTKGEKIML AIITKMTLTQ VSTWFANARR RLKKENKMTW 190 200 210 220 230 240 APRNKSEDED EDEGDATRSK DESPDKAQEG TETSAEDEGI SLHVDSLTDH SCSAESDGEK 250 260 270 280 290 300 LPCRAGDPLC ESGSECKDKY DDLEDDEDDD EEGERGLAPP KPVTSSPLTG LEAPLLSPPP 310 320 330 340 350 360 EAAPRGGRKT PQGSRTSPGA PPPASKPKLW SLAEIATSDL KQPSLGPGCG PPGLPAAAAP 370 380 390 400 410 420 ASTGAPPGGS PYPASPLLGR PLYYTSPFYG NYTNYGNLNA ALQGQGLLRY NSAAAAPGEA 430 440 450 460 470 LHTAPKAASD AGKAGAHPLE SHYRSPGGGY EPKKDASEGC TVVGGGVQPY L

References

[1]	"Homo sapiens mRNA." Sugiyama A., Inoue H., Oka M. Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Kidney EMBL BAD37140.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB188492 mRNA. Translation: BAD37140.1.
RefSeq	NP_001127694.1. NP_150366.1.
UniGene	Hs.282089
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000170561. Homo sapiens. [Contig view]
GeneID	153572.
KEGG	hsa:153572.
Organism-specific databases
HGNC	HGNC:14359. IRX2.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q68A19.
Gene expression databases
ArrayExpress	Q68A19.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR012287. Homeodomain-rel. IPR003893. Iroquois_homeo. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
ProDom	PD000010. Homeobox. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00389. HOX. 1 hit. SM00548. IRO. 1 hit. [Graphical view]
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
Other Resources
NextBio	87142.

Entry information

Entry name

Q68A19_HUMAN

Accession

Primary (citable) accession number: Q68A19

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	November 25, 2008
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)