Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Replicase polyprotein 1ab

Gene

rep

Organism
Simian hemorrhagic fever virus (SHFV)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

The replicase polyprotein 1ab is a multifunctional protein: it contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products.
The Nsp1 chain is essential for viral subgenomic mRNA synthesis.By similarity
The 3C-like serine proteinase chain is responsible for the majority of cleavages as it cleaves the C-terminus of the polyprotein.By similarity
The helicase chain, which contains a zinc finger structure, displays RNA and DNA duplex-unwinding activities with 5' to 3' polarity.By similarity

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation
ATP + H2O = ADP + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei63For Nsp1-alpha papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei130For Nsp1-alpha papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei246For Nsp1-beta papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei309For Nsp1-beta papain-like cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei378For Nsp2 cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei430For Nsp2 cysteine proteinase activityPROSITE-ProRule annotation1
Active sitei1502Charge relay system; for 3C-like serine proteinase activityPROSITE-ProRule annotation1
Active sitei1527Charge relay system; for 3C-like serine proteinase activityPROSITE-ProRule annotation1
Active sitei1580Charge relay system; for 3C-like serine proteinase activityPROSITE-ProRule annotation1
Metal bindingi2752Zinc 1PROSITE-ProRule annotation1
Metal bindingi2755Zinc 1PROSITE-ProRule annotation1
Metal bindingi2765Zinc 2PROSITE-ProRule annotation1
Metal bindingi2770Zinc 1PROSITE-ProRule annotation1
Metal bindingi2773Zinc 1PROSITE-ProRule annotation1
Metal bindingi2777Zinc 2PROSITE-ProRule annotation1
Metal bindingi2779Zinc 2PROSITE-ProRule annotation1
Metal bindingi2782Zinc 2PROSITE-ProRule annotation1
Metal bindingi2789Zinc 3PROSITE-ProRule annotation1
Metal bindingi2791Zinc 3PROSITE-ProRule annotation1
Metal bindingi2798Zinc 3PROSITE-ProRule annotation1
Metal bindingi2801Zinc 3PROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3 – 23C4-type; atypicalAdd BLAST21
Nucleotide bindingi2897 – 2904ATPBy similarity8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymerase, Serine protease, Thiol protease, Transferase
Biological processViral RNA replication
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Protein family/group databases

MEROPSiC32.002.

Names & Taxonomyi

Protein namesi
Recommended name:
Replicase polyprotein 1ab
Alternative name(s):
ORF1ab polyprotein
Cleaved into the following 15 chains:
Alternative name(s):
PCP1-alpha
Alternative name(s):
PCP1-beta
Alternative name(s):
CP2
Short name:
CP
Non-structural protein 3
Short name:
Nsp3
3C-like serine proteinase (EC:3.4.21.-)
Short name:
3CLSP
Alternative name(s):
Nsp4
Non-structural protein 5-6-7
Short name:
Nsp5-6-7
Non-structural protein 5
Short name:
Nsp5
Non-structural protein 6
Short name:
Nsp6
Non-structural protein 7-alpha
Short name:
Nsp7-alpha
Non-structural protein 7-beta
Short name:
Nsp7-beta
Non-structural protein 8
Short name:
Nsp8
RNA-directed RNA polymerase (EC:2.7.7.48)
Short name:
Pol
Short name:
RdRp
Alternative name(s):
Nsp9
Helicase (EC:3.6.4.12, EC:3.6.4.13)
Short name:
Hel
Alternative name(s):
Nsp10
Non-structural protein 11
Short name:
Nsp11
Non-structural protein 12
Short name:
Nsp12
Gene namesi
Name:rep
ORF Names:1a-1b
OrganismiSimian hemorrhagic fever virus (SHFV)
Taxonomic identifieri38143 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageNidoviralesArteriviridae
Virus hostiErythrocebus patas (Red guenon) (Cercopithecus patas) [TaxID: 9538]
Macaca (macaques) [TaxID: 9539]
Proteomesi
  • UP000106311 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei922 – 942HelicalSequence analysisAdd BLAST21
Transmembranei951 – 971HelicalSequence analysisAdd BLAST21
Transmembranei1019 – 1039HelicalSequence analysisAdd BLAST21
Transmembranei1239 – 1259HelicalSequence analysisAdd BLAST21
Transmembranei1316 – 1336HelicalSequence analysisAdd BLAST21
Transmembranei1345 – 1365HelicalSequence analysisAdd BLAST21
Transmembranei1381 – 1401HelicalSequence analysisAdd BLAST21
Transmembranei1673 – 1693HelicalSequence analysisAdd BLAST21
Transmembranei1711 – 1731HelicalSequence analysisAdd BLAST21
Transmembranei1744 – 1764HelicalSequence analysisAdd BLAST21
Transmembranei1784 – 1804HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm, Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000036712? – 350Nsp1-beta papain-like cysteine proteinaseBy similarity
ChainiPRO_00000367091 – 3595Replicase polyprotein 1abAdd BLAST3595
ChainiPRO_00000367111 – ?Nsp1-alpha papain-like cysteine proteinaseBy similarity
ChainiPRO_0000036713351 – 1236Nsp2 cysteine proteinaseBy similarityAdd BLAST886
ChainiPRO_00000367141237 – 1463Non-structural protein 3By similarityAdd BLAST227
ChainiPRO_00000367151464 – 16643C-like serine proteinaseBy similarityAdd BLAST201
ChainiPRO_00000367161665 – 2055Non-structural protein 5-6-7By similarityAdd BLAST391
ChainiPRO_00004231381665 – 1830Non-structural protein 5By similarityAdd BLAST166
ChainiPRO_00004231391831 – 1843Non-structural protein 6By similarityAdd BLAST13
ChainiPRO_00004231401844 – 1999Non-structural protein 7-alphaBy similarityAdd BLAST156
ChainiPRO_00004231412000 – 2055Non-structural protein 7-betaBy similarityAdd BLAST56
ChainiPRO_00000367172056 – 2746RNA-directed RNA polymeraseBy similarityAdd BLAST691
ChainiPRO_00000367182056 – 2104Non-structural protein 8By similarityAdd BLAST49
ChainiPRO_00000367192746 – 3195HelicaseBy similarityAdd BLAST450
ChainiPRO_00000367203196 – 3418Non-structural protein 11By similarityAdd BLAST223
ChainiPRO_00000367213419 – 3595Non-structural protein 12By similarityAdd BLAST177

Post-translational modificationi

Specific enzymatic cleavages in vivo by its own proteases yield mature proteins. There are two alternative pathways for processing. Either nsp4-5 is cleaved, which represents the major pathway or the nsp5-6 and nsp6-7 are processed, which represents the minor pathway. The major pathway occurs when nsp2 acts as cofactor for nsp4 (By similarity).By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei164 – 165Cleavage; by autolysisSequence analysis2
Sitei350 – 351Cleavage; by autolysisSequence analysis2
Sitei1236 – 1237Cleavage; by CP2By similarity2
Sitei1463 – 1464Cleavage; by 3CLSPBy similarity2
Sitei1664 – 1665Cleavage; by 3CLSPBy similarity2
Sitei1830 – 1831Cleavage; by 3CLSPBy similarity2
Sitei1843 – 1844Cleavage; by 3CLSPBy similarity2
Sitei1999 – 2000Cleavage; by 3CLSPBy similarity2
Sitei2055 – 2056Cleavage; by 3CLSPBy similarity2
Sitei2745 – 2746Cleavage; by 3CLSPBy similarity2
Sitei3195 – 3196Cleavage; by 3CLSPBy similarity2
Sitei3418 – 3419Cleavage; by 3CLSPBy similarity2

Structurei

3D structure databases

ProteinModelPortaliQ68772.
SMRiQ68772.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 164Peptidase C31PROSITE-ProRule annotationAdd BLAST109
Domaini239 – 350Peptidase C32PROSITE-ProRule annotationAdd BLAST112
Domaini633 – 736Peptidase C33PROSITE-ProRule annotationAdd BLAST104
Domaini1464 – 1664Peptidase S32PROSITE-ProRule annotationAdd BLAST201
Domaini2491 – 2625RdRp catalyticPROSITE-ProRule annotationAdd BLAST135
Domaini2746 – 2812AV ZBDPROSITE-ProRule annotationAdd BLAST67
Domaini2862 – 3022(+)RNA virus helicase ATP-bindingAdd BLAST161
Domaini3023 – 3157(+)RNA virus helicase C-terminalAdd BLAST135

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni922 – 1039HD1Add BLAST118
Regioni1239 – 1399HD2Add BLAST161
Regioni1687 – 1804HD3Add BLAST118

Domaini

The hydrophobic domains (HD) could mediate the membrane association of the replication complex and thereby alter the architecture of the host cell membrane.By similarity

Sequence similaritiesi

Belongs to the arteriviridae polyprotein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3 – 23C4-type; atypicalAdd BLAST21

Keywords - Domaini

Transmembrane, Transmembrane helix, Zinc-finger

Family and domain databases

Gene3Di3.30.40.20. 1 hit.
InterProiView protein in InterPro
IPR027351. (+)RNA_virus_helicase_core_dom.
IPR031932. Arteri_nsp7a.
IPR008743. Arterivirus_Nsp2_C33.
IPR023338. Arterivirus_NSP4_peptidase.
IPR008741. AV_PCPalpha.
IPR025773. AV_PCPbeta.
IPR027355. AV_ZBD.
IPR023183. Chymotrypsin-like_domain3.
IPR008760. EAV_peptidase_S32.
IPR027417. P-loop_NTPase.
IPR009003. Peptidase_S1_PA.
IPR001205. RNA-dir_pol_C.
IPR007094. RNA-dir_pol_PSvirus.
PfamiView protein in Pfam
PF16749. Arteri_nsp7a. 1 hit.
PF05411. Peptidase_C32. 2 hits.
PF05412. Peptidase_C33. 1 hit.
PF05579. Peptidase_S32. 1 hit.
PF00680. RdRP_1. 1 hit.
PF01443. Viral_helicase1. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS51538. AV_CP. 1 hit.
PS51493. AV_NSP4_PRO. 1 hit.
PS51539. AV_PCP_ALPHA. 1 hit.
PS51540. AV_PCP_BETA. 1 hit.
PS51652. AV_ZBD. 1 hit.
PS51657. PSRV_HELICASE. 1 hit.
PS50507. RDRP_SSRNA_POS. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by ribosomal frameshifting. AlignAdd to basket

Isoform Replicase polyprotein 1ab (identifier: Q68772-1) [UniParc]FASTAAdd to basket
Also known as: pp1ab

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MFCECPRSNL VVMCSGAFCC VLCGHRRRPR PASESDRAKY GPIVQYVEAR
60 70 80 90 100
VAHVYSGLEG RYCALEMIPI TYGNKFPYCK PLPVSFVIKT LAGVQGDLTR
110 120 130 140 150
LEETPLPGGY GVIPCWGPHL AAVGYLSPAH VGRDWFEGAT HAIVHIGSYG
160 170 180 190 200
GHERPTTIPF NTTGGDVYQL GTCTIVETID HVEWHAGVKP GTAICPLDRI
210 220 230 240 250
DFAQKVITAF PEGFLANKAW LGDKRGTLKV EADPETAALS FEHGRCWLKL
260 270 280 290 300
FPDPACELTT ASTFGYQLNC GVQGKYIARR LQTNGLKLVQ NQEGKFIAYT
310 320 330 340 350
FHRGSWLGHI GHADESVPPD CQIIARFDVL PYNEWSPLPL LKLPGKTYFG
360 370 380 390 400
GNASSVSWPE WKYDEQLLYA DSLTAGFCWL QLFPPLSRKS EAQRAILAQQ
410 420 430 440 450
VNNYGVTGTY LEYRLRQYGI VLAECDYGEH YIYAAASDSS IRHISPVPIH
460 470 480 490 500
DRHHVFVTRL TARFGAFDEG FDLGFGTRYG RRRGGGKKSG QSSGVRAPGR
510 520 530 540 550
TTPDLAGDWG KAVDDQEKTA SKVTTDKAMS TSEPAVVQVG CETKPVADAA
560 570 580 590 600
AVPASVNSTG CALLPVQADP CCTAGVAAKE SEPKAVAAPS IPITFGAPAG
610 620 630 640 650
ETLPVAASPL VVKKDKRCIS VKLTAKKALP KETFIPPPDG GCGVHAFAAI
660 670 680 690 700
QYHINTGHWP EQKPVVNWAY EAWTTNEDIG HMICSTETPA ALEPCLHARY
710 720 730 740 750
VVRLDSDHWV VDHYPNRPMC FVEACAHGWC SSLLSEPTGE EGEHLVDCSA
760 770 780 790 800
LYDCLGKFRN GTEFADTVLG LSKTAHCCNK RVPTPRKQAI MSLLNRPNCV
810 820 830 840 850
PCIAPPSQVR TVDPSQPAAP LPPVPRPRKR KAAAQQVSKV PSEQDPSLAH
860 870 880 890 900
DPPEKPDSVR PPKLGYLDRA WNNMLARTHK LHNLQQRVFG LYPQLLSMLL
910 920 930 940 950
PSGARPSTPR LLGCYFSMAV AMFFLFLGSP LFILCAVLAG VIAPSARYPK
960 970 980 990 1000
ILCCCLVVVY ICTLFADAIS SVCDNDDADC RAFLSDLGDR YSTNQPVYIT
1010 1020 1030 1040 1050
PGPATFFLAV SRNFFVVSVA LFPLHLLLLM VDVLLVIGVL CMDGYCFRCF
1060 1070 1080 1090 1100
SRCVRKAPEE VSLLTIPQSR VSRRFLLDIC DFYSAPPVDI IRLATGLNGC
1110 1120 1130 1140 1150
FRGDYSPIGS STSVITADKI DVKKVSCRTV CSFPSCPSEA VKVLHVLSVR
1160 1170 1180 1190 1200
GQMCAHNEQK VEKVDALPCK NPLFPYDLSS KKIVPVDSGT YEILSSIGCD
1210 1220 1230 1240 1250
MSHLVIGDGD FFKVMGVPRP SPFTVMRLRA CRVVGGGRIF RTALAAAWVL
1260 1270 1280 1290 1300
FFVCAGYWVQ MSTPCGIGTN DPFCKSSFGV PTYVNQGVCH GQYCASSKGV
1310 1320 1330 1340 1350
SRATSILTVR NPAVAPYIVL AACLVYLASV YVPGIIEVSL LVLNALLPAG
1360 1370 1380 1390 1400
PAISALRTLV MIIAAPHLSM KYIAFFCCTT AFVDFTSVVV VLTALLVGWI
1410 1420 1430 1440 1450
LARYTGIGGF VTPYDIHDVV KSQRDGVAVA NAPPNTYLGA VRRAALTGKP
1460 1470 1480 1490 1500
AFFVANNTGI VLEGLLREKT RASNSVSVYG VTCGSGGLFS DGNNTVCLTA
1510 1520 1530 1540 1550
THVCGNNKAV VDYQGTRYEA VFTTKGDYAS AVVPIPGAFP PLKFAPQSYT
1560 1570 1580 1590 1600
GRAYWYANTG VETGFVGTTG CLVFSGPGDS GSPIITPDGL IVGVHTGSDS
1610 1620 1630 1640 1650
KGSGAYTTPN GLTVSGPLSL KEMGAHYEGP IVDVPTRLPR NVHNDTKSVP
1660 1670 1680 1690 1700
QPLARLLESS INLEGGLGTI QLIIVAVVLW KYAVDPLSIP FVVAFFLLNE
1710 1720 1730 1740 1750
ILPKCLIRCF YNYSLFCLAA FSPLASRIFF IRLLTAALNR NPTALICHAC
1760 1770 1780 1790 1800
FAGIAVLNDF IILGDIRLAL RFTSFYVVGV NHDAIAIAVI GALVCVAACC
1810 1820 1830 1840 1850
LELFGLPQMA SVIGCHGSFD PTFLSRYVHE GIRQGVSSGF GTESLSTALA
1860 1870 1880 1890 1900
CALSEDELNF LAQAVDHKAI VSAIHVHKTL QDYILSKNAK ILRASLASVH
1910 1920 1930 1940 1950
ANHNASKALA SLDKFLQGTS TQLKPGDPVI LLGSTSAELV SVFSGDSEYI
1960 1970 1980 1990 2000
AEPIRSHPVA GTICTLCVVQ AKCEGGLVTQ VNGKFSPAKY LAVAGKVLAD
2010 2020 2030 2040 2050
HPDYKLENDG RFPRTREDRV KDSVQVDTVD IGSHTFKKMW NKTTGDVWYD
2060 2070 2080 2090 2100
IIMPESAANP LAVHDLDSAV AAIGMSKEIP EKDMNRLRAI ISKLQGLVSS
2110 2120 2130 2140 2150
EALNLLTAAG CTSADRSGLV ITLDYAKIIT HHARTRAFSS IDFKVVSPDE
2160 2170 2180 2190 2200
AMRTARLSPS PQPIIASFSD DKFLLLRRHP PSLLDVLTKG LDATCREPLH
2210 2220 2230 2240 2250
SPGDQGIDGY LWDFEAPHSK EAIWLSNQII SACAARRGDA PGCYPYKLHP
2260 2270 2280 2290 2300
VRGDPYRVGN VLKNTRFGDV TYTAVSDSDS PWLKVASINS GGCPVVTDRV
2310 2320 2330 2340 2350
LGSTIPVGSE IYLPTLPESV LDYLDSRPDC PTYYTQHGCE AAALQDLKKF
2360 2370 2380 2390 2400
NLSTQGFILP EVLNIVRNYL LGTIGYRPAI YKPSTVPSND SHAGINGLSF
2410 2420 2430 2440 2450
STKTLQALPD IDELCEKAIA EVWQTVTPVT LKKQFCSKAK TRTILGTNAM
2460 2470 2480 2490 2500
ASLALRALLS GVTQGFQLAG KNSPICLGKS KFDPCTFEVK GRCLETDLAS
2510 2520 2530 2540 2550
CDRSTPAIVR HFATKLLFEM ACAERALPLY VVNCCHDLIV TQTSAATKRG
2560 2570 2580 2590 2600
GLSSGDPVTS IANTIYSLVL YVQHMVLTLL ENGHPLSLKF LSGKLNFQDL
2610 2620 2630 2640 2650
YKLQAFIVYS DDLILLNESD DLPNFERWVP HLELALGFKV DPKKTVITSN
2660 2670 2680 2690 2700
PGFLGCEYRH GWLVPQKQRV LAALAYHVNA KDVHTYYINA TAILNDASAL
2710 2720 2730 2740 2750
SAFEPDWFDD LVIGLADCAR KDGYSFPGPA AFREFFSRVS GYQFEGKEVQ
2760 2770 2780 2790 2800
VCSICCSTAR TTSLCGMALC DFCAHRHYHP GCHVLSSFCK HVIGSNTCKM
2810 2820 2830 2840 2850
CSIPILKDRT KFAELLASDQ YRSVCTVEVT VVDGYTDAAP GRYSYQKKQY
2860 2870 2880 2890 2900
MLRKERRGCP LDLPDGKYSM KLLPNSCSGI CVPKAQENAT LSNFVVGPPG
2910 2920 2930 2940 2950
SGKTTFISNL LDDDAVVYCP THVSLIAYSK SLPAARFSVP RGQDPAEYGT
2960 2970 2980 2990 3000
PALSGPTLQL LSAGYVPGAK HYLDEACYAN PFDVFKLLSK TPITAIGDPA
3010 3020 3030 3040 3050
QLTPVGFDTP LYVFELMKKN ALHAIYRFGQ NICNAIQPCY STKLVSQRQG
3060 3070 3080 3090 3100
DTEVIFQTKF APRGKVLTPY HRDRVGAAVT IDSSQGSTYD VVTLYLPTKG
3110 3120 3130 3140 3150
SLTLARGLVG ITRARERLYV YDPHHQLAKY FNLQPSSTTI RPHAVVIDGK
3160 3170 3180 3190 3200
ARVMLSDKCY AAPEDFPGML CTARPATAAD RKILEETCLK LDFLESGSLS
3210 3220 3230 3240 3250
PLPRVCYNLG FYYSPDITKL LPIPSELAKH WPVATNRNNP EWPNRLVVSA
3260 3270 3280 3290 3300
TRLSPLSHPA VCAGYYVGDS LFVGTPNVTS YWLTKFLDGR AVPMEDSVYS
3310 3320 3330 3340 3350
TGRFEMDIRD YLDSAERDFA AKHPHAFIGD TKGTTVGGCH HITSQYLPHV
3360 3370 3380 3390 3400
LPADSVVKVG VSKPGVAHKA LCTVTDIYLP MLGSYTSPPT QSKVYKVNVD
3410 3420 3430 3440 3450
HKACKLMVWR DQTMYFQEGF DYHTLVDALR FVRLSSDGVY RVAPELTPMI
3460 3470 3480 3490 3500
GNRRLDLGAK PLRPVDLAIT PWDDPKCEFL VTHASPFDMS DEFLLVNAFD
3510 3520 3530 3540 3550
FIKEDLLGKS VTPVYFYKRL SEPLHFDQNL PPHVGAILSK APRFISLAKV
3560 3570 3580 3590
FNFCFTPTAC HCKVSVKTAT GDHMCKCSLS SDEFLSRFNP TVGTP
Note: Produced by -1 ribosomal frameshifting at the 1a-1b genes boundary.
Length:3,595
Mass (Da):391,443
Last modified:November 11, 2015 - v4
Checksum:i75E2CB1BE0242E18
GO
Isoform Replicase polyprotein 1a (identifier: Q68772-2) [UniParc]FASTAAdd to basket
Also known as: pp1a, ORF1a polyprotein

The sequence of this isoform differs from the canonical sequence as follows:
     2105-3595: Missing.

Note: Produced by conventional translation.
Show »
Length:2,104
Mass (Da):227,223
Checksum:i6C9623FD4D88B9F2
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0328942105 – 3595Missing in isoform Replicase polyprotein 1a. CuratedAdd BLAST1491

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF180391 Genomic RNA. Translation: AAA68933.3.
AF180391 Genomic RNA. Translation: AAB63390.4.
U28864 mRNA. Translation: AAB40002.1.
RefSeqiNP_203542.2. NC_003092.2.
YP_009109556.3. NC_003092.2. [Q68772-1]

Genome annotation databases

GeneIDi22220025.
KEGGivg:22220025.

Keywords - Coding sequence diversityi

Ribosomal frameshifting

Similar proteinsi

Entry informationi

Entry nameiRPOA_SHFV
AccessioniPrimary (citable) accession number: Q68772
Secondary accession number(s): P89132, Q87077
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: November 11, 2015
Last modified: July 5, 2017
This is version 113 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families