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Protein
Submitted name:

Coagulation factor VIII

Gene

F8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor VIIIImported
Gene namesi
Name:F8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88383. F8.

PTM / Processingi

Proteomic databases

PaxDbiQ684Q7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000031196.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033539.

Structurei

3D structure databases

ProteinModelPortaliQ684Q7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini27 – 136110Plastocyanin-likeInterPro annotationAdd
BLAST
Domaini161 – 285125Plastocyanin-likeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IJ6Y. Eukaryota.
ENOG4111F6G. LUCA.
HOGENOMiHOG000031471.
HOVERGENiHBG102538.

Family and domain databases

Gene3Di2.60.40.420. 2 hits.
InterProiIPR001117. Cu-oxidase.
IPR011707. Cu-oxidase_3.
IPR008972. Cupredoxin.
IPR014707. Factor_8.
[Graphical view]
PANTHERiPTHR10127:SF50. PTHR10127:SF50. 2 hits.
PfamiPF00394. Cu-oxidase. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q684Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYKKTVFVEY KDQLFNIAKP RPPWMGLLGP TIWTEVHDTV VITLKNMASH
60 70 80 90 100
PVSLHAVGVS YWKASEGDEY EDQTSQMEKE DDKVFPGESH TYVWQVLKEN
110 120 130 140 150
GPMASDPPCL TYSYMSHVDL VKDLNSGLIG ALLVCKEGSL SKERTQMLYQ
160 170 180 190 200
FVLLFAVFDE GKSWHSETND SYTQSMDSAS ARDWPKMHTV NGYVNRSLPG
210 220 230 240 250
LIGCHRKSVY WHVIGMGTTP EIHSIFLEGH TFFVRNHRQA SLEISPITFL
260 270 280 290 300
TAQTLLIDLG QFLLFCHISS HKHDGMEAYV KVDSCPEESQ WQKKNNNEEM
310 320 330 340
EDYDDDLYSE MDMFTLDYDS SPFIQIRSVA KKYPKTWIHY ISAEEEDWD
Length:349
Mass (Da):40,228
Last modified:October 11, 2004 - v1
Checksum:iC9911BF216E7F34B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei349 – 3491Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ627040 mRNA. Translation: CAF25309.1.
UniGeneiMm.1805.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ627040 mRNA. Translation: CAF25309.1.
UniGeneiMm.1805.

3D structure databases

ProteinModelPortaliQ684Q7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000033539.

Proteomic databases

PaxDbiQ684Q7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:88383. F8.

Phylogenomic databases

eggNOGiENOG410IJ6Y. Eukaryota.
ENOG4111F6G. LUCA.
HOGENOMiHOG000031471.
HOVERGENiHBG102538.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031196.

Family and domain databases

Gene3Di2.60.40.420. 2 hits.
InterProiIPR001117. Cu-oxidase.
IPR011707. Cu-oxidase_3.
IPR008972. Cupredoxin.
IPR014707. Factor_8.
[Graphical view]
PANTHERiPTHR10127:SF50. PTHR10127:SF50. 2 hits.
PfamiPF00394. Cu-oxidase. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ684Q7_MOUSE
AccessioniPrimary (citable) accession number: Q684Q7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.