Q67UX7 (P2C10_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable protein phosphatase 2C 10
Short name=OsPP2C10
EC=3.1.3.16

Gene names

Ordered Locus Names:	Os02g0149800, LOC_Os02g05630
ORF Names:	OSJNBa0050G13.3

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate.
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the PP2C family. Contains 1 PP2C-like domain.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Magnesium Manganese Metal-binding
Molecular function	Hydrolase Protein phosphatase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	defense response to bacterium Inferred from electronic annotation. Source: EnsemblPlants/Gramene protein dephosphorylation Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: EnsemblPlants/Gramene
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine phosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 348	348	Probable protein phosphatase 2C 10		PRO_0000363256
Regions
	Transmembrane	23 – 43	21	Helical; Potential
	Domain	81 – 321	241	PP2C-like
	Compositional bias	11 – 18	8	Poly-Ser
	Compositional bias	34 – 40	7	Poly-Val
Sites
	Metal binding	118	1	Manganese 1 By similarity
	Metal binding	118	1	Manganese 2 By similarity
	Metal binding	119	1	Manganese 1; via carbonyl oxygen By similarity
	Metal binding	280	1	Manganese 2 By similarity
	Metal binding	319	1	Manganese 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q67UX7 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 43405A0F8056495C	FASTA	348	37,568
	10 20 30 40 50 60 MHGRPSRPLA SSSSSSSSRV FSFFLAPRVF LFLVVVVVVV FLPGRSSCWW LEGTEELEEE 70 80 90 100 110 120 MGFAGDCSPV SGGGLSENGK FSYGYASAPG KRASMEDFYE TRIDGVDGET IGLFGVFDGH 130 140 150 160 170 180 GGARAAEYVK QHLFSNLIKH PKFISDIKSA IAETYNHTDS EFLKAESSHT RDAGSTASTA 190 200 210 220 230 240 ILVGDRLLVA NVGDSRAVVC RGGDAIAVSR DHKPDQSDER QRIEDAGGFV MWAGTWRVGG 250 260 270 280 290 300 VLAVSRAFGD KLLKQYVVAD PEIKEEIVDS SLEFLILASD GLWDVVSNKE AVDMVRPIQD 310 320 330 340 PEQAAKRLLQ EAYQRGSADN ITVVIVRFLE GTTTGGGPSR EAASDQNS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[3]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[4]	"Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis." Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y. BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP005412 Genomic DNA. Translation: BAD38042.1. AP008208 Genomic DNA. Translation: BAF07812.1. AK066016 mRNA. Translation: BAG89775.1.
RefSeq	NP_001045898.1. NM_001052433.1.
UniGene	Os.21078.
3D structure databases
HSSP	HSSP built from PDB template 1A6Q based on UniProtKB P35813.
ProteinModelPortal	Q67UX7.
ModBase	Search...
Proteomic databases
PRIDE	Q67UX7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os02g05630.1; LOC_Os02g05630.1; LOC_Os02g05630.
GeneID	4328306.
KEGG	osa:4328306.
Organism-specific databases
Gramene	Q67UX7.
Phylogenomic databases
eggNOG	COG0631.
HOGENOM	HOG000233896.
OMA	IRSSMED.
ProtClustDB	CLSN2692449.
Gene expression databases
ArrayExpress	Q67UX7.
Family and domain databases
Gene3D	3.60.40.10. 1 hit.
InterPro	IPR001932. PP2C-like. IPR000222. PP2C_Mn2_Asp60_BS. IPR015655. Protein_Pase_2C. [Graphical view]
PANTHER	PTHR13832. PTHR13832. 1 hit.
Pfam	PF00481. PP2C. 1 hit. [Graphical view]
SMART	SM00331. PP2C_SIG. 1 hit. SM00332. PP2Cc. 1 hit. [Graphical view]
SUPFAM	SSF81606. PP2C-related. 1 hit.
PROSITE	PS01032. PP2C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P2C10_ORYSJ

Accession

Primary (citable) accession number: Q67UX7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	October 11, 2004
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program