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Q67UP9

- P2C58_ORYSJ

UniProt

Q67UP9 - P2C58_ORYSJ

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Protein

Probable protein phosphatase 2C 58

Gene

Os06g0651600

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi57 – 571Manganese 1By similarity
Metal bindingi57 – 571Manganese 2By similarity
Metal bindingi58 – 581Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi272 – 2721Manganese 2By similarity
Metal bindingi320 – 3201Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 58 (EC:3.1.3.16)
Short name:
OsPP2C58
Gene namesi
Ordered Locus Names:Os06g0651600, LOC_Os06g44210
ORF Names:P0453H04.39-1, P0453H04.39-2
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 6

Organism-specific databases

GrameneiQ67UP9.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 368368Probable protein phosphatase 2C 58PRO_0000363305Add
BLAST

Expressioni

Gene expression databases

ExpressionAtlasiQ67UP9. baseline.

Structurei

3D structure databases

ProteinModelPortaliQ67UP9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 322301PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ67UP9.
KOiK17499.
OMAiTEDCCND.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 2 hits.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 2 hits.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q67UP9-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGVYLSTPKT EKLSEDGEND KLKFGLSSMQ GWRATMEDAH SALLDIDNDT
60 70 80 90 100
SFFGVFDGHG GRVVAKFCAK YLHREVLRSE AYSAGDLGNA AHKAFFRMDE
110 120 130 140 150
MMRGQRGWRE LQALGDKINQ ISGMIEGLIW SPRGSDSNDQ HDDWAFEEGP
160 170 180 190 200
HSDFAGPTCG STACVAIVRN SQLVVANAGD SRCVISRNGQ AYNLSRDHKP
210 220 230 240 250
ELEAERERIL KAGGYIQMGR VNGTINLSRA IGDIEFKQNK FLSPDKQMLT
260 270 280 290 300
ANPDINTVEL CDDDDFLVLA CDGIWDCMSS QQLVDFIHEH INTESSLSAV
310 320 330 340 350
CERVLDRCLA PSTLGGEGCD NMTMILVQFK KPISQNKNVS PAEQSAADKQ
360
PTGDTHWSEI HVTEESSS
Length:368
Mass (Da):40,591
Last modified:October 11, 2004 - v1
Checksum:i2ED54855F9A80D5C
GO
Isoform 2 (identifier: Q67UP9-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     276-368: Missing.

Note: No experimental confirmation available.

Show »
Length:275
Mass (Da):30,432
Checksum:iB278EA19D727FAD6
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei276 – 36893Missing in isoform 2. 1 PublicationVSP_036276Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005453 Genomic DNA. Translation: BAD38120.1.
AP005453 Genomic DNA. Translation: BAD38121.1.
AP008212 Genomic DNA. Translation: BAF20143.1.
AK112023 mRNA. Translation: BAG99518.1.
AK120711 mRNA. Translation: BAH00138.1.
RefSeqiNP_001058229.1. NM_001064764.1. [Q67UP9-1]
UniGeneiOs.46083.

Genome annotation databases

EnsemblPlantsiOS06T0651600-01; OS06T0651600-01; OS06G0651600. [Q67UP9-1]
GeneIDi4341693.
KEGGiosa:4341693.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005453 Genomic DNA. Translation: BAD38120.1 .
AP005453 Genomic DNA. Translation: BAD38121.1 .
AP008212 Genomic DNA. Translation: BAF20143.1 .
AK112023 mRNA. Translation: BAG99518.1 .
AK120711 mRNA. Translation: BAH00138.1 .
RefSeqi NP_001058229.1. NM_001064764.1. [Q67UP9-1 ]
UniGenei Os.46083.

3D structure databases

ProteinModelPortali Q67UP9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS06T0651600-01 ; OS06T0651600-01 ; OS06G0651600 . [Q67UP9-1 ]
GeneIDi 4341693.
KEGGi osa:4341693.

Organism-specific databases

Gramenei Q67UP9.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233896.
InParanoidi Q67UP9.
KOi K17499.
OMAi TEDCCND.

Gene expression databases

ExpressionAtlasi Q67UP9. baseline.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 2 hits.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 2 hits.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  3. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: cv. Nipponbare.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C58_ORYSJ
AccessioniPrimary (citable) accession number: Q67UP9
Secondary accession number(s): Q67UP8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: October 11, 2004
Last modified: November 26, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3