Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Formate dehydrogenase 2, mitochondrial

Gene

Os06g0486900

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Formate + NAD+ = CO2 + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei284 – 2841By similarity
Binding sitei308 – 3081NADBy similarity
Active sitei332 – 3321Proton donorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2022NADBy similarity
Nucleotide bindingi282 – 2843NADBy similarity
Nucleotide bindingi332 – 3354NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Formate dehydrogenase 2, mitochondrial (EC:1.2.1.2)
Alternative name(s):
NAD-dependent formate dehydrogenase 2
Short name:
FDH 2
Gene namesi
Ordered Locus Names:Os06g0486900, LOC_Os06g29220
ORF Names:P0404G03.13
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 6

Organism-specific databases

GrameneiQ67U69.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1818MitochondrionSequence AnalysisAdd
BLAST
Chaini19 – 378360Formate dehydrogenase 2, mitochondrialPRO_0000225339Add
BLAST

Proteomic databases

PaxDbiQ67U69.
PRIDEiQ67U69.

Expressioni

Gene expression databases

ExpressionAtlasiQ67U69. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os06g29220.1.

Structurei

3D structure databases

ProteinModelPortaliQ67U69.
SMRiQ67U69. Positions 31-372.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136703.
InParanoidiQ67U69.
KOiK00122.
OMAiELIYYDY.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q67U69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMWRAPSAA GQLLGRALAS TAAQTSAGSK KVVGVFYKGG EYADKNPNFV
60 70 80 90 100
GCVDSALGIR GWLESKGHRY IVTDDKEGIN CELEKHIEDA HVLITTPFHP
110 120 130 140 150
AYITAERIKK AKNLELLLTA GVGSDHIDLP AAAAAGLTVA EITGSNTVSV
160 170 180 190 200
AEDQLMRILL LLRNFLPGHH QIVNGEWNVA GIAHRTYDLE GKTVGTVGAG
210 220 230 240 250
RIGRLLLQRL KPFNCNLMYH DRVKIDPELE KEIGAKYEED LDAMLPKCDV
260 270 280 290 300
VVINMPLTEK TRGMFNKERI AKMKKGVTIV NNARGAIMDT QAVADACASG
310 320 330 340 350
HVAGYGGDVW FPQPAPKDHP WRYMPNHAMT PHCSGTTIDG QLRYAAGVKD
360 370
MLDRYFKGED FPAQNYIVKA GQLASQYQ
Length:378
Mass (Da):41,267
Last modified:October 11, 2004 - v1
Checksum:i7DFE10FAABC0E2EF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti41 – 411E → K in AK064610 (PubMed:12869764).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005656 Genomic DNA. Translation: BAD38302.1.
AK064610 mRNA. No translation available.
RefSeqiNP_001057667.1. NM_001064202.1.
UniGeneiOs.14187.

Genome annotation databases

EnsemblPlantsiOS06T0486900-01; OS06T0486900-01; OS06G0486900.
GeneIDi4341070.
KEGGiosa:4341070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005656 Genomic DNA. Translation: BAD38302.1.
AK064610 mRNA. No translation available.
RefSeqiNP_001057667.1. NM_001064202.1.
UniGeneiOs.14187.

3D structure databases

ProteinModelPortaliQ67U69.
SMRiQ67U69. Positions 31-372.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os06g29220.1.

Proteomic databases

PaxDbiQ67U69.
PRIDEiQ67U69.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS06T0486900-01; OS06T0486900-01; OS06G0486900.
GeneIDi4341070.
KEGGiosa:4341070.

Organism-specific databases

GrameneiQ67U69.

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136703.
InParanoidiQ67U69.
KOiK00122.
OMAiELIYYDY.

Gene expression databases

ExpressionAtlasiQ67U69. baseline.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR029752. D-isomer_DH_CS1.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEiPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiFDH2_ORYSJ
AccessioniPrimary (citable) accession number: Q67U69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: October 11, 2004
Last modified: June 24, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.