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Q67SX4 (Q67SX4_SYMTH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase HAMAP MF_00197
Short name=DAP epimerase HAMAP MF_00197
EC=5.1.1.7 HAMAP MF_00197
Gene names
Name:dapF HAMAP MF_00197
Ordered Locus Names:STH234
OrganismSymbiobacterium thermophilum [Complete proteome] [HAMAP]
Taxonomic identifier2734 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197 SAAS SAAS018510

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197 SAAS SAAS018510

Subcellular location

Cytoplasm By similarity HAMAP MF_00197 SAAS SAAS018510.

Sequence similarities

Belongs to the diaminopimelate epimerase family. HAMAP MF_00197

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis HAMAP MF_00197 SAAS SAAS018510
   Cellular componentCytoplasm HAMAP MF_00197 SAAS SAAS018510
   Molecular functionIsomerase HAMAP MF_00197 SAAS SAAS018510
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site761 By similarity HAMAP MF_00197
Active site2131 By similarity HAMAP MF_00197

Sequences

Sequence LengthMass (Da)Tools
Q67SX4 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: E709569E2E6A1415

FASTA27229,543
        10         20         30         40         50         60 
MVRFTKMEGA GNDYIYVNNL VEQVPEERLP ALARALSDRH FGVGADGLIV ILPPAEPGYD 

        70         80         90        100        110        120 
FRFRMFNADG SEGEMCGNGM RCFARYCYER GLTARRRMRV QTAAGCVVPE VLVDDAGSFA 

       130        140        150        160        170        180 
GVRVDLGPPR ILGDRRIAAE GREYPVTVVD TGVPHIVIFV DDVDAVDLAK VGPQLERHPD 

       190        200        210        220        230        240 
FPARVNVNFA EAQGPAELRA RTWERGSGLT LACGTGASAV LVAACLKGRT GRAARVRMPG 

       250        260        270 
GDLQVEWDEA TGHVFLTGPA EFVCDGVFLR EF

« Hide

References

[1]"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T / IAM 14863.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006840 Genomic DNA. Translation: BAD39219.1.
RefSeqYP_074063.1. NC_006177.1.

3D structure databases

ProteinModelPortalQ67SX4.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2980141.
GenomeReviewsGene locus STH234 in contig AP006840_GR.
KEGGsth:STH234.
NMPDRfig|292459.1.peg.231.
PATRIC23778531. VBISymThe116959_0237.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG399442.
OMAFMTGPAT.

Enzyme and pathway databases

BioCycSTHE292459:STH234-MONOMER.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ67SX4_SYMTH
AccessionPrimary (citable) accession number: Q67SX4
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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