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Protein

Putative fluoride ion transporter CrcB 1

Gene

crcB1

Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-583-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 1UniRule annotation
Gene namesi
Name:crcB1UniRule annotation
Ordered Locus Names:STH541
OrganismiSymbiobacterium thermophilum (strain T / IAM 14863)
Taxonomic identifieri292459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium
Proteomesi
  • UP000000417 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei4 – 2421HelicalUniRule annotationAdd
BLAST
Transmembranei36 – 5621HelicalUniRule annotationAdd
BLAST
Transmembranei67 – 8721HelicalUniRule annotationAdd
BLAST
Transmembranei103 – 12321HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 124124Putative fluoride ion transporter CrcB 1PRO_0000110198Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi292459.STH541.

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108BGT. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiWLAIELM.
OrthoDBiPOG091H017F.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q67S17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWVLIGVAG AAGAVARLLV GAWIDGRPGG RAFPWGTFAV NIAGSLLLGL
60 70 80 90 100
LTGLVVGRGW LAPEVKVVLG AGFLGAFTTF STWLLDLHEA LRRGDHRAAF
110 120
VNAALSTGLG LLAAWLGLAL GWGR
Length:124
Mass (Da):12,775
Last modified:October 11, 2004 - v1
Checksum:i1681E3FB5984D5E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD39526.1.
RefSeqiWP_011194675.1. NC_006177.1.

Genome annotation databases

EnsemblBacteriaiBAD39526; BAD39526; STH541.
KEGGisth:STH541.
PATRICi23779158. VBISymThe116959_0526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD39526.1.
RefSeqiWP_011194675.1. NC_006177.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292459.STH541.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD39526; BAD39526; STH541.
KEGGisth:STH541.
PATRICi23779158. VBISymThe116959_0526.

Phylogenomic databases

eggNOGiENOG4108BGT. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiWLAIELM.
OrthoDBiPOG091H017F.

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-583-MONOMER.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCRCB1_SYMTH
AccessioniPrimary (citable) accession number: Q67S17
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: October 11, 2004
Last modified: September 7, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.