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Protein

Putative fluoride ion transporter CrcB 1

Gene

crcB1

Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-583-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 1UniRule annotation
Gene namesi
Name:crcB1UniRule annotation
Ordered Locus Names:STH541
OrganismiSymbiobacterium thermophilum (strain T / IAM 14863)
Taxonomic identifieri292459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium
Proteomesi
  • UP000000417 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei4 – 2421HelicalUniRule annotationAdd
BLAST
Transmembranei36 – 5621HelicalUniRule annotationAdd
BLAST
Transmembranei67 – 8721HelicalUniRule annotationAdd
BLAST
Transmembranei103 – 12321HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 124124Putative fluoride ion transporter CrcB 1PRO_0000110198Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi292459.STH541.

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108BGT. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiTWMLETH.
OrthoDBiEOG6091KP.

Family and domain databases

HAMAPiMF_00454. CrcB.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q67S17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWVLIGVAG AAGAVARLLV GAWIDGRPGG RAFPWGTFAV NIAGSLLLGL
60 70 80 90 100
LTGLVVGRGW LAPEVKVVLG AGFLGAFTTF STWLLDLHEA LRRGDHRAAF
110 120
VNAALSTGLG LLAAWLGLAL GWGR
Length:124
Mass (Da):12,775
Last modified:October 11, 2004 - v1
Checksum:i1681E3FB5984D5E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD39526.1.
RefSeqiWP_011194675.1. NC_006177.1.

Genome annotation databases

EnsemblBacteriaiBAD39526; BAD39526; STH541.
KEGGisth:STH541.
PATRICi23779158. VBISymThe116959_0526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD39526.1.
RefSeqiWP_011194675.1. NC_006177.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292459.STH541.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD39526; BAD39526; STH541.
KEGGisth:STH541.
PATRICi23779158. VBISymThe116959_0526.

Phylogenomic databases

eggNOGiENOG4108BGT. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiTWMLETH.
OrthoDBiEOG6091KP.

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-583-MONOMER.

Family and domain databases

HAMAPiMF_00454. CrcB.
InterProiIPR003691. CrcB.
[Graphical view]
PfamiPF02537. CRCB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
    Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
    Nucleic Acids Res. 32:4937-4944(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T / IAM 14863.

Entry informationi

Entry nameiCRCB1_SYMTH
AccessioniPrimary (citable) accession number: Q67S17
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: October 11, 2004
Last modified: January 20, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.