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Q67QU3 (FENR_SYMTH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:STH965
OrganismSymbiobacterium thermophilum [Complete proteome] [HAMAP]
Taxonomic identifier2734 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364979

Sites

Binding site181FAD By similarity
Binding site371FAD By similarity
Binding site451FAD By similarity
Binding site501FAD By similarity
Binding site921FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1271FAD; via amide nitrogen By similarity
Binding site2901FAD By similarity
Binding site3311FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q67QU3 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 7AF1805EB6E584FD

FASTA33636,683
        10         20         30         40         50         60 
MSGTKELYDV TLIGAGPTGL FGVFYAGMRG MKTKVIEALP EVGGQLAALY PEKDIFDVAG 

        70         80         90        100        110        120 
FPRISAKRLV EQCKEQADSA NPDATYVFNQ RVDKLNRLED GTFELVTHTG ERHYSKAVII 

       130        140        150        160        170        180 
TAGIGAFEPN RIPNESARQY EGKGVFYSVT NLPQFEGKRV LVIGGGDSAV DYALMVEPIA 

       190        200        210        220        230        240 
AEVTLIHRRD GFRAHEESLK KLAASRVHVK VFYELRRVEG DGNWVKKATI FDNRTGEETT 

       250        260        270        280        290        300 
IDVDCVIIGT GFKASLGSML EWGLEIENKR QIVVNSKGET NIPGVYAAGD ICWYPGKIRL 

       310        320        330 
IATGFGEVAT AVNNAKAFID PGSAAFPGHS SEQRNK

« Hide

References

[1]"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T / IAM 14863.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006840 Genomic DNA. Translation: BAD39950.1.
RefSeqYP_074794.1. NC_006177.1.

3D structure databases

HSSPHSSP built from PDB template 1F6M based on UniProtKB P0A9P4.
ProteinModelPortalQ67QU3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2980582.
GenomeReviewsGene locus STH965 in contig AP006840_GR.
KEGGsth:STH965.
NMPDRfig|292459.1.peg.925.
PATRIC23780062. VBISymThe116959_0961.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG669726.
OMAFQVFELG.

Enzyme and pathway databases

BioCycSTHE292459:STH965-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_SYMTH
AccessionPrimary (citable) accession number: Q67QU3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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