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Q67QB6 (Q67QB6_SYMTH) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
EC=1.8.4.8 HAMAP MF_00063
Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP MF_00063
PAPS reductase, thioredoxin dependent HAMAP MF_00063
PAPS sulfotransferase HAMAP MF_00063
PAdoPS reductase HAMAP MF_00063
Gene names
Name:cysH HAMAP MF_00063
Ordered Locus Names:STH1142
OrganismSymbiobacterium thermophilum [Complete proteome] [HAMAP]
Taxonomic identifier2734 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite By similarity. HAMAP MF_00063 SAAS SAAS002500

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 SAAS SAAS002500

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 SAAS SAAS002500

Subcellular location

Cytoplasm By similarity HAMAP MF_00063 SAAS SAAS002500.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily. HAMAP MF_00063

Sequences

Sequence LengthMass (Da)Tools
Q67QB6 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 512407A8DF3DC50D

FASTA23326,421
        10         20         30         40         50         60 
MAEKRWSPEE IAAAARSLEG QGPVAALRWA YEQFAPEEIA FACSFGAEDV ALAHMISRVA 

        70         80         90        100        110        120 
PGAQVFYLDT DFLFPETYRT IEAVRAAYPL RIRRVSPALT PREQAERYGD ELWSRDPDLC 

       130        140        150        160        170        180 
CSLRKVEPLR EVLRGLKAWI TGIRRAQSPT RAGAQVVEWD RKFGLVKVNP LVDWKDADVW 

       190        200        210        220        230 
KYILEHNVPY NPLHDRGYPS IGCTHCTRPV RPGEDPRAGR WSGFAKTECG LHQ

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References

[1]"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T / IAM 14863.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006840 Genomic DNA. Translation: BAD40127.1.
RefSeqYP_074971.1. NC_006177.1.

3D structure databases

ProteinModelPortalQ67QB6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2981014.
GenomeReviewsGene locus STH1142 in contig AP006840_GR.
KEGGsth:STH1142.
NMPDRfig|292459.1.peg.1096.
PATRIC23780440. VBISymThe116959_1141.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG758022.
OMAFEETLAY.
ProtClustDBCLSK2463128.

Enzyme and pathway databases

BioCycSTHE292459:STH1142-MONOMER.

Family and domain databases

HAMAPMF_00063. CysH.
[Tree]
InterProIPR011798. APS_reductase.
IPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00390.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsTIGR02055. APS_reductase. 1 hit.
TIGR00434. CysH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ67QB6_SYMTH
AccessionPrimary (citable) accession number: Q67QB6
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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