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Protein

DNA-directed RNA polymerase subunit omega

Gene

rpoZ

Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-1409-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit omegaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP omega subunitUniRule annotation
Alternative name(s):
RNA polymerase omega subunitUniRule annotation
Transcriptase subunit omegaUniRule annotation
Gene namesi
Name:rpoZUniRule annotation
Ordered Locus Names:STH1340
OrganismiSymbiobacterium thermophilum (strain T / IAM 14863)
Taxonomic identifieri292459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium
Proteomesi
  • UP000000417 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6969DNA-directed RNA polymerase subunit omegaPRO_0000237515Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi292459.STH1340.

Structurei

3D structure databases

ProteinModelPortaliQ67PR8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase subunit omega family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41084KE. Bacteria.
COG1758. LUCA.
HOGENOMiHOG000245722.
KOiK03060.
OMAiHQMVESK.
OrthoDBiEOG6Q5NV5.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SMARTiSM01409. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q67PR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKPSLDQLM HLVDSKYTLV ILAARRARDL QDGKHQMVES KSNKPVTIAL
60
EELAAGKLFF ERGKPTPLG
Length:69
Mass (Da):7,703
Last modified:October 11, 2004 - v1
Checksum:i4DCAFC00D2BBBF36
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD40325.1.
RefSeqiWP_011195471.1. NC_006177.1.

Genome annotation databases

EnsemblBacteriaiBAD40325; BAD40325; STH1340.
KEGGisth:STH1340.
PATRICi23780831. VBISymThe116959_1336.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD40325.1.
RefSeqiWP_011195471.1. NC_006177.1.

3D structure databases

ProteinModelPortaliQ67PR8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292459.STH1340.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD40325; BAD40325; STH1340.
KEGGisth:STH1340.
PATRICi23780831. VBISymThe116959_1336.

Phylogenomic databases

eggNOGiENOG41084KE. Bacteria.
COG1758. LUCA.
HOGENOMiHOG000245722.
KOiK03060.
OMAiHQMVESK.
OrthoDBiEOG6Q5NV5.

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-1409-MONOMER.

Family and domain databases

Gene3Di3.90.940.10. 1 hit.
HAMAPiMF_00366. RNApol_bact_RpoZ.
InterProiIPR003716. DNA-dir_RNA_pol_omega.
IPR006110. Pol_omega/K/RPB6.
IPR012293. RNAP_RPB6_omega.
[Graphical view]
PfamiPF01192. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SMARTiSM01409. RNA_pol_Rpb6. 1 hit.
[Graphical view]
SUPFAMiSSF63562. SSF63562. 1 hit.
TIGRFAMsiTIGR00690. rpoZ. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
    Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
    Nucleic Acids Res. 32:4937-4944(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T / IAM 14863.

Entry informationi

Entry nameiRPOZ_SYMTH
AccessioniPrimary (citable) accession number: Q67PR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 11, 2004
Last modified: May 11, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.