Q67PJ6 (Q67PJ6_SYMTH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
Ordered Locus Names:	STH1412

Organism

Symbiobacterium thermophilum [Complete proteome] [HAMAP]

Taxonomic identifier

2734 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134 SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134 SAAS SAAS013798
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134 SAAS SAAS013798
Molecular function	Decarboxylase HAMAP MF_00134 SAAS SAAS013798 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q67PJ6 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 70F0984150C851A3	FASTA	270	28,202
	10 20 30 40 50 60 MAAARRARPL ADVIAAARAA PPPRGFLRAL GGPPSGAGAG GTEVRVIAEV KKASPSKGVI 70 80 90 100 110 120 RPDFDPVAIA RAYAEGGAAC LSVLTDERYF QGSLAYLAAI REAVALPLLR KDFIIEEYQV 130 140 150 160 170 180 HEARAAGADA ILLIVAAFCG DCAGGRTPED LNRLAALARE LGMDVLTEVH TADELALAVA 190 200 210 220 230 240 SGAPLIGINN RDLRTFHTTL EVTERLAPLV PPDRLLVSES GIWTHDDLRR VAAAGARAVL 250 260 270 VGESLMRQPD VAAALRALRG SPEGSVPDNS

References

[1]

"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism." Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T. Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T / IAM 14863.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006840 Genomic DNA. Translation: BAD40397.1.
RefSeq	YP_075241.1. NC_006177.1.
3D structure databases
ProteinModelPortal	Q67PJ6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2982087.
GenomeReviews	Gene locus STH1412 in contig AP006840_GR.
KEGG	sth:STH1412.
NMPDR	fig|292459.1.peg.1356.
PATRIC	23780979. VBISymThe116959_1410.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG540956.
OMA	VESLGMT.
Enzyme and pathway databases
BioCyc	STHE292459:STH1412-MONOMER.
Family and domain databases
HAMAP	MF_00134_A. IGPS_A. [Tree] MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q67PJ6_SYMTH

Accession

Primary (citable) accession number: Q67PJ6

Entry history

Integrated into UniProtKB/TrEMBL:	October 11, 2004
Last sequence update:	October 11, 2004
Last modified:	December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)