Reviewed, UniProtKB/Swiss-Prot Q67NP7 (COMB_SYMTH)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	STH1711

Organism

Symbiobacterium thermophilum [Complete proteome] [HAMAP]

Taxonomic identifier

2734 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 233	233	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081473

Sequences

	Sequence		Length	Mass (Da)
	Q67NP7-1 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 211315F45620BCDF	FASTA	233	25,210
	10 20 30 40 50 60 MVNIPPAEEL AGRVAVVIDV LRATTTICTA LANGADTVVP ILSPEEAFQV ARDNPDRQFL 70 80 90 100 110 120 LGGERKAVLI PGFHCDNSPL EYTEARVKGR PILFTTTNGT RAIRRAAGAD RVYIASLLNA 130 140 150 160 170 180 PAVGRELARL EVDVAICCAG THDQFSLEDT VCAGAILEYM AGPDRPVETN DMGLVARELF 190 200 210 220 230 RRYDGRLADL LHLSSHGQNL VRLGMQDDLL FCAQLGTLTI LPVFTEGQVV LLE

References

[1]

"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism." Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T. Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T / IAM 14863.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP006840 Genomic DNA. Translation: BAD40696.1.
RefSeq	YP_075540.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2979970.
GenomeReviews	Gene locus STH1711 in contig AP006840_GR.
KEGG	sth:STH1711.
NMPDR	fig|292459.1.peg.1649.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q67NP7.
OMA	Q67NP7. DFICSGY.
Enzyme and pathway databases
BioCyc	STHE292459:STH1711-MON.
BRENDA	3.1.3.71. 20615.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COMB_SYMTH

Accession

Primary (citable) accession number: Q67NP7

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 21, 2004
Last sequence update:	October 11, 2004
Last modified:	June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)