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Reviewed, UniProtKB/Swiss-Prot Q67NP7 (COMB_SYMTH)

Last modified June 16, 2009. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71
Gene names
Name: comB
Ordered Locus Names: STH1711
OrganismSymbiobacterium thermophilum [Complete proteome] [HAMAP]
Taxonomic identifier2734 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiales Family XVIII. Incertae SedisSymbiobacterium

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the comB family.

Ontologies

Keywords
   LigandMagnesium
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcoenzyme M biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular function2-phosphosulfolactate phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490
PRO_0000081473

Sequences

Sequence LengthMass (Da)Tools
Q67NP7-1 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 211315F45620BCDF

FASTA23325,210
        10         20         30         40         50         60 
MVNIPPAEEL AGRVAVVIDV LRATTTICTA LANGADTVVP ILSPEEAFQV ARDNPDRQFL 

        70         80         90        100        110        120 
LGGERKAVLI PGFHCDNSPL EYTEARVKGR PILFTTTNGT RAIRRAAGAD RVYIASLLNA 

       130        140        150        160        170        180 
PAVGRELARL EVDVAICCAG THDQFSLEDT VCAGAILEYM AGPDRPVETN DMGLVARELF 

       190        200        210        220        230 
RRYDGRLADL LHLSSHGQNL VRLGMQDDLL FCAQLGTLTI LPVFTEGQVV LLE 

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References

[1]"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T / IAM 14863.

Cross-references

Sequence databases

AP006840 Genomic DNA. Translation: BAD40696.1.
RefSeqYP_075540.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2979970.
GenomeReviewsGene locus STH1711 in contig AP006840_GR.
KEGGsth:STH1711.
NMPDRfig|292459.1.peg.1649.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ67NP7.
OMAQ67NP7. DFICSGY.

Enzyme and pathway databases

BioCycSTHE292459:STH1711-MON.
BRENDA3.1.3.71. 20615.

Family and domain databases

HAMAPMF_00490.
[Tree]
InterProIPR005238. 2-PSlactate_phosphatase.
[Graphical view]
Gene3DG3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
PfamPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOMB_SYMTH
AccessionPrimary (citable) accession number: Q67NP7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: October 11, 2004
Last modified: June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents