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Protein

Probable 2-phosphosulfolactate phosphatase

Gene

comB

Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-1780-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 2-phosphosulfolactate phosphataseUniRule annotation (EC:3.1.3.71UniRule annotation)
Gene namesi
Name:comBUniRule annotation
Ordered Locus Names:STH1711
OrganismiSymbiobacterium thermophilum (strain T / IAM 14863)
Taxonomic identifieri292459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium
Proteomesi
  • UP000000417 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 233233Probable 2-phosphosulfolactate phosphatasePRO_0000081473Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi292459.STH1711.

Structurei

3D structure databases

ProteinModelPortaliQ67NP7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ComB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108N5B. Bacteria.
COG2045. LUCA.
HOGENOMiHOG000232676.
KOiK05979.
OMAiFRATSCM.
OrthoDBiEOG6SNDT4.

Family and domain databases

Gene3Di3.90.1560.10. 1 hit.
HAMAPiMF_00490. ComB.
InterProiIPR005238. ComB-like.
IPR022995. ProB_Pase_ComB.
[Graphical view]
PfamiPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMiSSF142823. SSF142823. 1 hit.

Sequencei

Sequence statusi: Complete.

Q67NP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNIPPAEEL AGRVAVVIDV LRATTTICTA LANGADTVVP ILSPEEAFQV
60 70 80 90 100
ARDNPDRQFL LGGERKAVLI PGFHCDNSPL EYTEARVKGR PILFTTTNGT
110 120 130 140 150
RAIRRAAGAD RVYIASLLNA PAVGRELARL EVDVAICCAG THDQFSLEDT
160 170 180 190 200
VCAGAILEYM AGPDRPVETN DMGLVARELF RRYDGRLADL LHLSSHGQNL
210 220 230
VRLGMQDDLL FCAQLGTLTI LPVFTEGQVV LLE
Length:233
Mass (Da):25,210
Last modified:October 11, 2004 - v1
Checksum:i211315F45620BCDF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD40696.1.

Genome annotation databases

EnsemblBacteriaiBAD40696; BAD40696; STH1711.
KEGGisth:STH1711.
PATRICi23781579. VBISymThe116959_1710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD40696.1.

3D structure databases

ProteinModelPortaliQ67NP7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292459.STH1711.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD40696; BAD40696; STH1711.
KEGGisth:STH1711.
PATRICi23781579. VBISymThe116959_1710.

Phylogenomic databases

eggNOGiENOG4108N5B. Bacteria.
COG2045. LUCA.
HOGENOMiHOG000232676.
KOiK05979.
OMAiFRATSCM.
OrthoDBiEOG6SNDT4.

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-1780-MONOMER.

Family and domain databases

Gene3Di3.90.1560.10. 1 hit.
HAMAPiMF_00490. ComB.
InterProiIPR005238. ComB-like.
IPR022995. ProB_Pase_ComB.
[Graphical view]
PfamiPF04029. 2-ph_phosp. 1 hit.
[Graphical view]
SUPFAMiSSF142823. SSF142823. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
    Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
    Nucleic Acids Res. 32:4937-4944(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T / IAM 14863.

Entry informationi

Entry nameiCOMB_SYMTH
AccessioniPrimary (citable) accession number: Q67NP7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: October 11, 2004
Last modified: January 20, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.