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Q67ND6 (Q67ND6_SYMTH) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Ordered Locus Names:STH1822
OrganismSymbiobacterium thermophilum [Complete proteome] [HAMAP]
Taxonomic identifier2734 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q67ND6 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 43687C008069032B

FASTA37239,777
        10         20         30         40         50         60 
MRVGVVRELK AYENRVAMTP AGVMAMVRAG HEVYVEHDAG RGSGFDDSEY VAAGARILPS 

        70         80         90        100        110        120 
NEDVWATADM IVKVKEPLPP EYDLMREGQI IFTYLHLAAE PELTRKLIER KSIAIAYETV 

       130        140        150        160        170        180 
QPADRSLPLL TPMSEVAGRM AVQIGAHYLE KAHGGRGVLL GGVPGVAPGR VAIIGGGTVG 

       190        200        210        220        230        240 
TNAAKIALGM GAHVTILDIN ADRLRYLDDI FGSRVETRIS NEFEIANAVA QADLVIGAVL 

       250        260        270        280        290        300 
IPGAKAPKLV TAEMVKRMAP GSVIVDVAID QGGSVETIDR VTTHQDPVYE RFGVVHYAVA 

       310        320        330        340        350        360 
NIPGAVPRTS TWALTNVTLP YALKLANLGW KEALRQDPAL AKGANVVSGH VTYPAVAEAH 

       370 
GLEYVELDNV LR

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References

[1]"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T / IAM 14863.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006840 Genomic DNA. Translation: BAD40807.1.
RefSeqYP_075651.1. NC_006177.1.

3D structure databases

ProteinModelPortalQ67ND6.
SMRQ67ND6. Positions 1-360.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2981991.
GenomeReviewsGene locus STH1822 in contig AP006840_GR.
KEGGsth:STH1822.
PATRIC23781805. VBISymThe116959_1822.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289735.
OMAVAHGHEV.

Enzyme and pathway databases

BioCycSTHE292459:STH1822-MONOMER.

Family and domain databases

InterProIPR008143. Ala_DH/PNT_CS2.
IPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
PROSITEPS00837. ALADH_PNT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ67ND6_SYMTH
AccessionPrimary (citable) accession number: Q67ND6
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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