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Q67L76 (ACKA_SYMTH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:STH2585
OrganismSymbiobacterium thermophilum [Complete proteome] [HAMAP]
Taxonomic identifier2734 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Acetate kinase HAMAP MF_00020
PRO_0000107629

Sequences

Sequence LengthMass (Da)Tools
Q67L76 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: E018C7C53B3D3B06

FASTA39843,191
        10         20         30         40         50         60 
MKILVLNCGS SSIKYQLLDM ETESVLAIGK VERVGMEDAI FEYKGAGEKI KEIGTILDHT 

        70         80         90        100        110        120 
AGVRKVLKAL TDPVHGVIQA PEEIAAVGHR VVHGGEAFVK SVIITDEVKR TLRELFDLAP 

       130        140        150        160        170        180 
LHNPANLTGI LAAEAALPHA PGVAVFDTAF HATMPRKAFL YALPYAMYKG HKVRRYGFHG 

       190        200        210        220        230        240 
TSHKYVSQRA ADLLGRPLEE VNLITCHLGN GSSVTAVQGG KSVDTSMGFT PLAGLIMGTR 

       250        260        270        280        290        300 
AGDLDPGVIP YIMAREEIGI SEVNSMLNKH SGILGISGIS SDMRQIEEEM EKGDPRAVET 

       310        320        330        340        350        360 
FEMMEYRLRK YIGAYAAVLG RVDGIVFTGG IGENSPLFRK AVCQNLGFLG VTFDEEANNC 

       370        380        390 
RGQERIISGP DSKVAVMVIP TNEELMIARE TAELIRNR

« Hide

References

[1]"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T / IAM 14863.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP006840 Genomic DNA. Translation: BAD41570.1.
RefSeqYP_076414.1. NC_006177.1.

3D structure databases

ProteinModelPortalQ67L76.
SMRQ67L76. Positions 1-396.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2981578.
GenomeReviewsGene locus STH2585 in contig AP006840_GR.
KEGGsth:STH2585.
NMPDRfig|292459.1.peg.2475.
PATRIC23783342. VBISymThe116959_2577.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMAQTMPEHV.

Enzyme and pathway databases

BioCycSTHE292459:STH2585-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_SYMTH
AccessionPrimary (citable) accession number: Q67L76
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: October 11, 2004
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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