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Protein
Submitted name:

O-acetylhomoserine sulfhydrylase

Gene

STH2681

Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. pyridoxal phosphate binding Source: InterPro
  2. transferase activity, transferring alkyl or aryl (other than methyl) groups Source: InterPro

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-2765-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
O-acetylhomoserine sulfhydrylaseImported
Gene namesi
Ordered Locus Names:STH2681Imported
OrganismiSymbiobacterium thermophilum (strain T / IAM 14863)Imported
Taxonomic identifieri292459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium
ProteomesiUP000000417: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi292459.STH2681.

Structurei

3D structure databases

ProteinModelPortaliQ67KY0.
SMRiQ67KY0. Positions 13-429.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the trans-sulfuration enzymes family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246417.
KOiK01740.
OMAiNIYGRMG.
OrthoDBiEOG67DPN3.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PTHR11808:SF12. PTHR11808:SF12. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q67KY0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPDRSDAASD RYRPATLVVH AGWQPDPLTG AQAVPIYQTT AYAFQSTEHA
60 70 80 90 100
RQLFSLEAEG NIYTRINNPT TAAFEARVAA LEGGIGAVAF ASGHAALAAT
110 120 130 140 150
VLAICNAGDE IVTSSSLYGG TYNLFATTLP KWGITARFVD AHDLAGFHRA
160 170 180 190 200
ITPRTRLIFG EVIGNPRLDV FDIAGVAAIA HEHGLPLVID NTFATPMLCR
210 220 230 240 250
PIEHGADLVI HSATKWLGGH GVAMGGVVVD SGNFDWNSPR FPGFTEPDPS
260 270 280 290 300
YHGVRYAVDF GRAGFITKVR AQMLRDLGGC QSPFNAFLLL LGLDTLALRM
310 320 330 340 350
RAISENALEI ARYLSEHPAV AWVRYPGLPS HPDHALAQRY LTGGFGGMLV
360 370 380 390 400
FGLKGGLEAG ARFIDSVRLF SHVANVGDAR SLVIHPASTT HSQLTPAQRE
410 420 430
AAGVGDDLIR VSVGFEDVAD LIADLEQALE KAAGA
Length:435
Mass (Da):46,329
Last modified:October 11, 2004 - v1
Checksum:i9A6D595970EF5F83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD41666.1.
RefSeqiYP_076510.1. NC_006177.1.

Genome annotation databases

EnsemblBacteriaiBAD41666; BAD41666; STH2681.
GeneIDi2979826.
KEGGisth:STH2681.
PATRICi23783538. VBISymThe116959_2674.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA. Translation: BAD41666.1.
RefSeqiYP_076510.1. NC_006177.1.

3D structure databases

ProteinModelPortaliQ67KY0.
SMRiQ67KY0. Positions 13-429.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi292459.STH2681.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD41666; BAD41666; STH2681.
GeneIDi2979826.
KEGGisth:STH2681.
PATRICi23783538. VBISymThe116959_2674.

Phylogenomic databases

HOGENOMiHOG000246417.
KOiK01740.
OMAiNIYGRMG.
OrthoDBiEOG67DPN3.

Enzyme and pathway databases

BioCyciSTHE292459:GJMM-2765-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 1 hit.
PTHR11808:SF12. PTHR11808:SF12. 1 hit.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism."
    Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T.
    Nucleic Acids Res. 32:4937-4944(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T / IAM 14863Imported.

Entry informationi

Entry nameiQ67KY0_SYMTH
AccessioniPrimary (citable) accession number: Q67KY0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: February 4, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.