Q67K94 (GCP_SYMTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	STH2921

Organism

Symbiobacterium thermophilum [Complete proteome] [HAMAP]

Taxonomic identifier

2734 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303581

Sequences

	Sequence		Length	Mass (Da)
	Q67K94 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: 7A1B8FD0201E7754	FASTA	341	35,728
	10 20 30 40 50 60 MKGLSEGLIL GIESSCDETA AAVVAGGRRV LSNTVASQVD LFRKYGGVVP EIASRRHLEL 70 80 90 100 110 120 ILPVIREALQ MAGVTLEQID AVAVTHGPGL VGTLLVGLSA AKALAFGLDK PLIGVNHLQG 130 140 150 160 170 180 HIYANFLVEP PPEFPLVCLV VSGGHTDLIY MAGHGRMELL GRTLDDAAGE AFDKVARSVG 190 200 210 220 230 240 LGYPGGPQVE KLARSGDPEA VPLPRAHTEG PYDFSFSGLK TAVLQYVQRT GPLNDQQRAD 250 260 270 280 290 300 LAASFQRAVT SVLVERTVKA AEAKGVRQVI LAGGVAANGA LREEMRAALE PRGIRLGYPP 310 320 330 340 PVLCTDNAAM IAAAGYYLWR AGVRHDLDLN AVPGLGLGIG G

References

[1]

"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism." Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T. Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T / IAM 14863.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006840 Genomic DNA. Translation: BAD41904.1.
RefSeq	YP_076748.1. NC_006177.1.
3D structure databases
ProteinModelPortal	Q67K94.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2979438.
GenomeReviews	Gene locus STH2921 in contig AP006840_GR.
KEGG	sth:STH2921.
NMPDR	fig|292459.1.peg.2795.
PATRIC	23784025. VBISymThe116959_2901.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
Enzyme and pathway databases
BioCyc	STHE292459:STH2921-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_SYMTH

Accession

Primary (citable) accession number: Q67K94

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program