ID   Q67K49_SYMTH            Unreviewed;       572 AA.
AC   Q67K49;
DT   11-OCT-2004, integrated into UniProtKB/TrEMBL.
DT   11-OCT-2004, sequence version 1.
DT   27-MAR-2024, entry version 81.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:BAD41949.1};
GN   OrderedLocusNames=STH2966 {ECO:0000313|EMBL:BAD41949.1};
OS   Symbiobacterium thermophilum (strain T / IAM 14863).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Symbiobacteriaceae;
OC   Symbiobacterium.
OX   NCBI_TaxID=292459 {ECO:0000313|EMBL:BAD41949.1, ECO:0000313|Proteomes:UP000000417};
RN   [1] {ECO:0000313|EMBL:BAD41949.1, ECO:0000313|Proteomes:UP000000417}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T / IAM 14863 {ECO:0000313|Proteomes:UP000000417};
RX   PubMed=15383646; DOI=10.1093/nar/gkh830;
RA   Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K.,
RA   Ikeda H., Hattori M., Beppu T.;
RT   "Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium
RT   that depends on microbial commensalism.";
RL   Nucleic Acids Res. 32:4937-4944(2004).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AP006840; BAD41949.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q67K49; -.
DR   STRING; 292459.STH2966; -.
DR   KEGG; sth:STH2966; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_9; -.
DR   Proteomes; UP000000417; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000417};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        120..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          142..199
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          246..531
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   572 AA;  60512 MW;  2B0FA44A332088CC CRC64;
     MAYAASAYTA TAEAGYRERY RTLEGEVSQG IQGLLDAAED DRESQLVAEV QRRYAEFSAF
     VGRVVSRDSF NEAQIRVMSR SLQSERNKII EALNELLTHL QERVDETALA AEQAVRFTRL
     VTIGTTGAAV LFGFVVAFFV ARNIVFPVLA LARAAQRMAA GDLSQDVTAG LAGLRGRDEL
     AEMARSFHQM VNYLRGLVVG MQGTVQAGLE VSGDLAATAD QAALSAQDAA RAVAIVAEGT
     SQQAASAQEM NRMIEDLRQS VQQIAAGASR SSADLEEAST LLHRAAQDLT RMTGQTDQVA
     RGAQQAAQMA AEGSRAVDEM VQGMTRIEQA VGDSAARMDE LAKASAQIGQ ITAVISEIAD
     QTNLLALNAA IEAARAGEHG RGFAVVADEV RKLAERSAAS AREISELIAR IQARTDQVVE
     SMTVASNEVQ QSTELAARSG RRLEQILQTV TRAAEDVSHV AEAARSLQRQ VDVAMKAFEG
     VAAVTAENTA ATEEMAEGTA RVLSSIGAIV DAAQQNAAAA EQVSAAIEEL TAVADGVAGH
     AQNLNQIALW LKEQVGNFQV GEGEGEHGNA SS
//