Q67JX0 (RS4A_SYMTH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4 A

Gene names

Name:	rpsD1
Synonyms:	rpsD
Ordered Locus Names:	STH3048

Organism

Symbiobacterium thermophilum [Complete proteome] [HAMAP]

Taxonomic identifier

2734 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiales Family XVIII. Incertae Sedis › Symbiobacterium

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP MF_01306_B With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP MF_01306_B
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 207	207	30S ribosomal protein S4 A HAMAP MF_01306_B		PRO_0000228933
Regions
	Domain	98 – 161	64	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	Q67JX0 [UniParc]. Last modified October 11, 2004. Version 1. Checksum: F97E0B4426F83FAD	FASTA	207	23,916
	10 20 30 40 50 60 MARYTGPVCR LCRREGVKLY LKGEKCYSDK CPIVKRATPP GQHGASRRKP TEYAIQLREK 70 80 90 100 110 120 QKARRYYGVL ERQFERYFEM ASRKKGVTGE VLLQTLERRL DNVVYRMGFA ASRAEARQIV 130 140 150 160 170 180 KHSHIEVNGR KVNIPSYLVR EGDVVAVRES SREHKRIKEL AAAATRTVPA WLSVDPEALR 190 200 GTVLRLPNRD EIDTPVQEQL IVEFYSR

References

[1]

"Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism." Ueda K., Yamashita A., Ishikawa J., Shimada M., Watsuji T., Morimura K., Ikeda H., Hattori M., Beppu T. Nucleic Acids Res. 32:4937-4944(2004) [PubMed: 15383646] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T / IAM 14863.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP006840 Genomic DNA. Translation: BAD42030.1.
RefSeq	YP_076874.1. NC_006177.1.
3D structure databases
ProteinModelPortal	Q67JX0.
SMR	Q67JX0. Positions 2-207.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2979361.
GenomeReviews	Gene locus STH3048 in contig AP006840_GR.
KEGG	sth:STH3048.
NMPDR	fig|292459.1.peg.2920.
PATRIC	23784277. VBISymThe116959_3027.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285740.
OMA	QLVVELY.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	STHE292459:STH3048-MONOMER.
Family and domain databases
HAMAP	MF_01306_B. Ribosomal_S4_B. [Tree]
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.1050.10. G3DSA:1.10.1050.10. 1 hit. G3DSA:3.10.290.10. G3DSA:3.10.290.10. 1 hit.
KO	K02986.
PANTHER	PTHR11831. Ribosomal_S4. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. RpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4A_SYMTH

Accession

Primary (citable) accession number: Q67JX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
Last sequence update:	October 11, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program