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Protein

Protein-arginine kinase

Gene

mcsB

Organism
Symbiobacterium thermophilum (strain T / IAM 14863)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the specific phosphorylation of arginine residues in proteins.UniRule annotation

Catalytic activityi

ATP + a [protein]-L-arginine = ADP + a [protein]-N(omega)-phospho-L-arginine.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei93ATPUniRule annotation1
Binding sitei127ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi27 – 31ATPUniRule annotation5
Nucleotide bindingi178 – 182ATPUniRule annotation5
Nucleotide bindingi209 – 214ATPUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein-arginine kinaseUniRule annotation (EC:2.7.14.1UniRule annotation)
Gene namesi
Name:mcsBUniRule annotation
Ordered Locus Names:STH3134
OrganismiSymbiobacterium thermophilum (strain T / IAM 14863)
Taxonomic identifieri292459 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesSymbiobacteriaceaeSymbiobacterium
Proteomesi
  • UP000000417 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002120381 – 353Protein-arginine kinaseAdd BLAST353

Interactioni

Protein-protein interaction databases

STRINGi292459.STH3134

Structurei

3D structure databases

ProteinModelPortaliQ67JN4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 256Phosphagen kinase C-terminalUniRule annotationAdd BLAST233

Sequence similaritiesi

Belongs to the ATP:guanido phosphotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41066A3 Bacteria
COG3869 LUCA
HOGENOMiHOG000082112
KOiK19405
OMAiACPTNVG
OrthoDBiPOG091H027W

Family and domain databases

CDDicd07930 bacterial_phosphagen_kinase, 1 hit
HAMAPiMF_00602 Prot_Arg_kinase, 1 hit
InterProiView protein in InterPro
IPR023660 Arg_Kinase
IPR000749 ATP-guanido_PTrfase
IPR022415 ATP-guanido_PTrfase_AS
IPR022414 ATP-guanido_PTrfase_cat
IPR014746 Gln_synth/guanido_kin_cat_dom
PANTHERiPTHR11547 PTHR11547, 1 hit
PfamiView protein in Pfam
PF00217 ATP-gua_Ptrans, 1 hit
SUPFAMiSSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00112 PHOSPHAGEN_KINASE, 1 hit
PS51510 PHOSPHAGEN_KINASE_C, 1 hit

Sequencei

Sequence statusi: Complete.

Q67JN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGWNELVSRA ESRWMEGTGP HADIVLSSRI RLARNLDDLP FPQRMSEPDT
60 70 80 90 100
ERLLQAAEAG VREINLVGFP SRVELYRLAD TTPLDRQILV EKHLISPQQS
110 120 130 140 150
KEVMAKAVAI SEDEAISIMV NEEDHLRIQV LASGLQLQEA WRVASQVDDA
160 170 180 190 200
LEQRLQFAFD EQLGYLTACP TNVGTGLRAS VMMHLPALVL TQQAGRLFHN
210 220 230 240 250
LSQLGLVVRG LYGEGTEAAG QIFQISNQTS LGKAEEEIIA NLEAIARTVI
260 270 280 290 300
DTEEQARRHL YGEMRLQIED RVSRAYGILT TARMISSEEA MRLLSDVRLG
310 320 330 340 350
VALGVVPKID YRILNELLVA MQPACLQRQA GRELNPLERD VRRAALIRAR

LSA
Length:353
Mass (Da):39,405
Last modified:October 11, 2004 - v1
Checksum:i33E19F14BC005834
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006840 Genomic DNA Translation: BAD42116.1

Genome annotation databases

EnsemblBacteriaiBAD42116; BAD42116; STH3134
KEGGisth:STH3134

Similar proteinsi

Entry informationi

Entry nameiMCSB_SYMTH
AccessioniPrimary (citable) accession number: Q67JN4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: October 11, 2004
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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