Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q67IX6 (PDI14_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein disulfide isomerase-like 1-4
Short name=OsPDIL1-4
EC=5.3.4.1
Alternative name(s):
Protein disulfide isomerase-like 2-1
Short name=OsPDIL2-1
Gene names
Name:PDIL1-4
Synonyms:PDIL2-1
Ordered Locus Names:Os02g0100100, LOC_Os02g01010
ORF Names:OsJ_04977, OSJNOa183H18.2
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds. May play a role in storage protein biogenesis By similarity.

Catalytic activity

Catalyzes the rearrangement of -S-S- bonds in proteins.

Subcellular location

Endoplasmic reticulum lumen Probable.

Sequence similarities

Belongs to the protein disulfide isomerase family.

Contains 2 thioredoxin domains.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 563541Protein disulfide isomerase-like 1-4
PRO_0000400031

Regions

Domain46 – 180135Thioredoxin 1
Domain394 – 523130Thioredoxin 2
Motif560 – 5634Prevents secretion from ER By similarity

Sites

Active site1021Nucleophile By similarity
Active site1051Nucleophile By similarity
Active site4441Nucleophile By similarity
Active site4471Nucleophile By similarity
Site1661Lowers pKa of C-terminal Cys of first active site By similarity
Site4451Contributes to redox potential value By similarity
Site4461Contributes to redox potential value By similarity
Site5091Lowers pKa of C-terminal Cys of second active site By similarity

Amino acid modifications

Glycosylation821N-linked (GlcNAc...) Potential
Glycosylation1851N-linked (GlcNAc...) Potential
Glycosylation3151N-linked (GlcNAc...) Potential
Disulfide bond102 ↔ 105Redox-active By similarity
Disulfide bond444 ↔ 447Redox-active By similarity

Sequences

Sequence LengthMass (Da)Tools
Q67IX6 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: F6862C4A2C65491F

FASTA56362,253
        10         20         30         40         50         60 
MRSRSLLLVA LATLLLHASA SASDDDLDYL IDNADDIPAN DPDGWLQEGS PDDDDDDDLF 

        70         80         90        100        110        120 
HHGQAQDHPI DETHVFLLSA ANFSDFLASH RHVMVEFYAP WCAHCQALAP DYAAAAADLS 

       130        140        150        160        170        180 
PLAHQVALAK VDATEDTDLA QKYDVQGFPT ILFFIDGVPK DYNGARTKEA IVSWVNKKLA 

       190        200        210        220        230        240 
PGVQNITTVD EAEKILTGED KAILAVLDSL SGAHSDEIAA ASRLEDAINF YQTSNPDVAK 

       250        260        270        280        290        300 
LFHLDPAAKR PSLVLLKKQE EEKLTFYDGP FKASAIADFV SANKLPLVNT LTQETAPSIF 

       310        320        330        340        350        360 
DNPIKKQILL FVVANESSKF LPIFKEASKS FKGKLLFVFV ERDNEEVGEP VANYFGITGQ 

       370        380        390        400        410        420 
ETTVLAYTGN EDARNFFLDG EISVENIKRF AEDFLEEKLT PFYKSEPVPE SNEGDVKIVV 

       430        440        450        460        470        480 
GKNLDQIVLD ESKDALLEIY APWCGHCQEL EPTYNKLGKH LRGIDSLVIA KMDGTANEHP 

       490        500        510        520        530        540 
RAKPDGFPTI LFYPAGKKSF EPITFEGDRT VVEMYKFIKK HASIPFKLKR PDSSATKTEK 

       550        560 
DQSTASTNLR GERSSGTNFK DEL

« Hide

References

« Hide 'large scale' references
[1]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[3]"Sequencing and characterization of telomere and subtelomere regions on rice chromosomes 1S, 2S, 2L, 6L, 7S, 7L and 8S."
Mizuno H., Wu J., Kanamori H., Fujisawa M., Namiki N., Saji S., Katagiri S., Katayose Y., Sasaki T., Matsumoto T.
Plant J. 46:206-217(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[6]"Phylogenetic analyses identify 10 classes of the protein disulfide isomerase family in plants, including single-domain protein disulfide isomerase-related proteins."
Houston N.L., Fan C., Xiang J.Q., Schulze J.M., Jung R., Boston R.S.
Plant Physiol. 137:762-778(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
[7]"The protein disulfide isomerase gene family in bread wheat (T. aestivum L.)."
d'Aloisio E., Paolacci A.R., Dhanapal A.P., Tanzarella O.A., Porceddu E., Ciaffi M.
BMC Plant Biol. 10:101-101(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008208 Genomic DNA. Translation: BAF07493.1.
AP006851 Genomic DNA. Translation: BAD38565.1.
CM000139 Genomic DNA. Translation: EEE56114.1.
AK071514 mRNA. Translation: BAG92533.1.
RefSeqNP_001045579.1. NM_001052114.1.
UniGeneOs.13477.

3D structure databases

ProteinModelPortalQ67IX6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os02g01010.1; LOC_Os02g01010.1; LOC_Os02g01010.
GeneID4327971.
KEGGdosa:Os02t0100100-01.
osa:4327971.

Organism-specific databases

GrameneQ67IX6.

Phylogenomic databases

eggNOGCOG0526.
KOK09580.
OMAKSFEPIT.
ProtClustDBCLSN2692351.

Gene expression databases

ArrayExpressQ67IX6.

Family and domain databases

Gene3D3.40.30.10. 4 hits.
InterProIPR005788. Disulphide_isomerase.
IPR005792. Prot_disulphide_isomerase.
IPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamPF00085. Thioredoxin. 2 hits.
[Graphical view]
PRINTSPR00421. THIOREDOXIN.
SUPFAMSSF52833. Thiordxn-like_fd. 4 hits.
TIGRFAMsTIGR01130. ER_PDI_fam. 1 hit.
TIGR01126. pdi_dom. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePDI14_ORYSJ
AccessionPrimary (citable) accession number: Q67IX6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: October 11, 2004
Last modified: April 3, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents