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Protein

Protein disulfide isomerase-like 1-4

Gene

PDIL1-4

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds. May play a role in storage protein biogenesis (By similarity).By similarity

Catalytic activityi

Catalyzes the rearrangement of -S-S- bonds in proteins.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei102NucleophileBy similarity1
Active sitei105NucleophileBy similarity1
Sitei166Lowers pKa of C-terminal Cys of first active siteBy similarity1
Active sitei444NucleophileBy similarity1
Sitei445Contributes to redox potential valueBy similarity1
Sitei446Contributes to redox potential valueBy similarity1
Active sitei447NucleophileBy similarity1
Sitei509Lowers pKa of C-terminal Cys of second active siteBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein disulfide isomerase-like 1-4 (EC:5.3.4.1)
Short name:
OsPDIL1-4
Alternative name(s):
Protein disulfide isomerase-like 2-1
Short name:
OsPDIL2-1
Gene namesi
Name:PDIL1-4
Synonyms:PDIL2-1
Ordered Locus Names:Os02g0100100, LOC_Os02g01010
ORF Names:OsJ_04977, OSJNOa183H18.2
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000040003123 – 563Protein disulfide isomerase-like 1-4Add BLAST541

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi82N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi102 ↔ 105Redox-activePROSITE-ProRule annotation
Glycosylationi185N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi315N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi444 ↔ 447Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ67IX6.
PRIDEiQ67IX6.

Expressioni

Gene expression databases

GenevisibleiQ67IX6. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g01010.1.

Structurei

3D structure databases

ProteinModelPortaliQ67IX6.
SMRiQ67IX6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 180Thioredoxin 1PROSITE-ProRule annotationAdd BLAST135
Domaini394 – 523Thioredoxin 2PROSITE-ProRule annotationAdd BLAST130

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi560 – 563Prevents secretion from ERPROSITE-ProRule annotation4

Sequence similaritiesi

Belongs to the protein disulfide isomerase family.Curated

Keywords - Domaini

Redox-active center, Repeat, Signal

Phylogenomic databases

eggNOGiKOG0190. Eukaryota.
COG0526. LUCA.
InParanoidiQ67IX6.
KOiK09580.
OMAiQYGVRGY.
OrthoDBiEOG093607A9.

Family and domain databases

InterProiView protein in InterPro
IPR005788. Disulphide_isomerase.
IPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
PfamiView protein in Pfam
PF00085. Thioredoxin. 2 hits.
SUPFAMiSSF52833. SSF52833. 4 hits.
TIGRFAMsiTIGR01130. ER_PDI_fam. 1 hit.
TIGR01126. pdi_dom. 1 hit.
PROSITEiView protein in PROSITE
PS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q67IX6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSRSLLLVA LATLLLHASA SASDDDLDYL IDNADDIPAN DPDGWLQEGS
60 70 80 90 100
PDDDDDDDLF HHGQAQDHPI DETHVFLLSA ANFSDFLASH RHVMVEFYAP
110 120 130 140 150
WCAHCQALAP DYAAAAADLS PLAHQVALAK VDATEDTDLA QKYDVQGFPT
160 170 180 190 200
ILFFIDGVPK DYNGARTKEA IVSWVNKKLA PGVQNITTVD EAEKILTGED
210 220 230 240 250
KAILAVLDSL SGAHSDEIAA ASRLEDAINF YQTSNPDVAK LFHLDPAAKR
260 270 280 290 300
PSLVLLKKQE EEKLTFYDGP FKASAIADFV SANKLPLVNT LTQETAPSIF
310 320 330 340 350
DNPIKKQILL FVVANESSKF LPIFKEASKS FKGKLLFVFV ERDNEEVGEP
360 370 380 390 400
VANYFGITGQ ETTVLAYTGN EDARNFFLDG EISVENIKRF AEDFLEEKLT
410 420 430 440 450
PFYKSEPVPE SNEGDVKIVV GKNLDQIVLD ESKDALLEIY APWCGHCQEL
460 470 480 490 500
EPTYNKLGKH LRGIDSLVIA KMDGTANEHP RAKPDGFPTI LFYPAGKKSF
510 520 530 540 550
EPITFEGDRT VVEMYKFIKK HASIPFKLKR PDSSATKTEK DQSTASTNLR
560
GERSSGTNFK DEL
Length:563
Mass (Da):62,253
Last modified:October 11, 2004 - v1
Checksum:iF6862C4A2C65491F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006851 Genomic DNA. Translation: BAD38565.1.
AP008208 Genomic DNA. Translation: BAF07493.1.
AP014958 Genomic DNA. Translation: BAS76496.1.
CM000139 Genomic DNA. Translation: EEE56114.1.
AK071514 mRNA. Translation: BAG92533.1.
RefSeqiXP_015627045.1. XM_015771559.1.
UniGeneiOs.13477.

Genome annotation databases

EnsemblPlantsiOS02T0100100-01; OS02T0100100-01; OS02G0100100.
GeneIDi4327971.
GrameneiOS02T0100100-01; OS02T0100100-01; OS02G0100100.
KEGGiosa:4327971.

Similar proteinsi

Entry informationi

Entry nameiPDI14_ORYSJ
AccessioniPrimary (citable) accession number: Q67IX6
Secondary accession number(s): A0A0P0VDI0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: October 11, 2004
Last modified: August 30, 2017
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families