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Q67C40 (MPK7_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitogen-activated protein kinase 7

Short name=MAP kinase 7
EC=2.7.11.24
Alternative name(s):
MAP kinase 6
OsMAPK6
Gene names
Name:MPK7
Synonyms:MAPK6
Ordered Locus Names:Os05g0566400, LOC_Os05g49140
ORF Names:OJ1781_H11.5, OJ1781_H11.6
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza

Protein attributes

Sequence length569 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulation

Activated by threonine and tyrosine phosphorylation By similarity.

Induction

By jasmonic acid (JA) and infection with rice blast fungus (M.grisea). Ref.3

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Post-translational modification

Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

Contains 1 protein kinase domain.

Ontologies

Keywords
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Serine/threonine-protein kinase
Transferase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcortical microtubule organization

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

MAP kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 569569Mitogen-activated protein kinase 7
PRO_0000239750

Regions

Domain13 – 304292Protein kinase
Nucleotide binding19 – 279ATP By similarity
Motif175 – 1773TXY

Sites

Active site1391Proton acceptor By similarity
Binding site421ATP By similarity

Amino acid modifications

Modified residue1751Phosphothreonine By similarity
Modified residue1771Phosphotyrosine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q67C40 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: F2A244BB1D2D8D91

FASTA56964,669
        10         20         30         40         50         60 
MDFFSEYGDS SRYKIQEIVG KGSYGVVCSA IDQHTGDKVA IKKIHNIFEH LSDAARILRE 

        70         80         90        100        110        120 
IKLLRLLRHP DIVEIKHIML PPSRRDFKDI YVVFELMDTD LHQVIKANDD LTKEHHQFFL 

       130        140        150        160        170        180 
YQMLRALKYI HTANVYHRDL KPKNILANAN CKLKICDFGL ARVAFNDTPT TVFWTDYVAT 

       190        200        210        220        230        240 
RWYRAPELCG SFFSKYSPAI DTWSIGCIFA EILTGKPLFP GKNVVHQLDL MTDLLGTPSM 

       250        260        270        280        290        300 
DAISRIRNDK ARRYLSSMRR KQPVPFSEKF PNVDPLALKL LQRLLAFDPK DRPTAEEALA 

       310        320        330        340        350        360 
DPYFKGLAKV EREPSCQPIS KMEFEFERRK VTKDDIKELI FREILEYHPQ LLKDYMNGSE 

       370        380        390        400        410        420 
NTSFLYPSAV DNFRRQFAIL EENGGKSGAL DRKHVSLPRA TTVHSTSIPP NEGLDATSQV 

       430        440        450        460        470        480 
TQRIPTARPG RTVGPVLPFE NPGAADPHSA RRVVRNPMVP PAAANKSGYS YNLKSDYSDR 

       490        500        510        520        530        540 
QHQEELEKDR VQYRPAQHLM DAKVAPDTAP DIRSSQYYFT RSAPRTDLTD RAALQGSMLY 

       550        560 
GIAPFNGIAA VAGGYSKVGA VQYGVSRMY 

« Hide

References

« Hide 'large scale' references
[1]"A novel MAP kinase-OsMAPK6 involved in the developmental regulation for rice plants."
Wang Y.D., Chen X., Ye Z., Wei M.L.
Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"A fine physical map of the rice chromosome 5."
Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J., Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F., Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.
Mol. Genet. Genomics 274:337-345(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
Reyna N.S., Yang Y.
Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION, NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY366480 mRNA. Translation: AAR11478.1.
AC120986 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalQ67C40.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ67C40.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

GrameneQ67C40.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000233024.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMPK7_ORYSJ
AccessionPrimary (citable) accession number: Q67C40
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations