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Protein

Mitogen-activated protein kinase 7

Gene

MPK7

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei42ATPPROSITE-ProRule annotation1
Active sitei139Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 27ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-4086398 Ca2+ pathway
R-OSA-5687128 MAPK6/MAPK4 signaling

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinase 7 (EC:2.7.11.24)
Short name:
MAP kinase 7
Alternative name(s):
MAP kinase 6
OsMAPK6
Gene namesi
Name:MPK7
Synonyms:MAPK6
Ordered Locus Names:Os05g0566400, LOC_Os05g49140
ORF Names:OJ1781_H11.5, OJ1781_H11.6
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002397501 – 569Mitogen-activated protein kinase 7Add BLAST569

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei175PhosphothreonineBy similarity1
Modified residuei177PhosphotyrosineBy similarity1

Post-translational modificationi

Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ67C40
PRIDEiQ67C40

Expressioni

Inductioni

By jasmonic acid (JA) and infection with rice blast fungus (M.grisea).1 Publication

Gene expression databases

ExpressionAtlasiQ67C40 differential
GenevisibleiQ67C40 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os05g49140.1

Structurei

3D structure databases

ProteinModelPortaliQ67C40
SMRiQ67C40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 304Protein kinasePROSITE-ProRule annotationAdd BLAST292

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi175 – 177TXY3

Domaini

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0660 Eukaryota
ENOG410XNY0 LUCA
HOGENOMiHOG000233024
InParanoidiQ67C40

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR003527 MAP_kinase_CS
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS01351 MAPK, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

Q67C40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFFSEYGDS SRYKIQEIVG KGSYGVVCSA IDQHTGDKVA IKKIHNIFEH
60 70 80 90 100
LSDAARILRE IKLLRLLRHP DIVEIKHIML PPSRRDFKDI YVVFELMDTD
110 120 130 140 150
LHQVIKANDD LTKEHHQFFL YQMLRALKYI HTANVYHRDL KPKNILANAN
160 170 180 190 200
CKLKICDFGL ARVAFNDTPT TVFWTDYVAT RWYRAPELCG SFFSKYSPAI
210 220 230 240 250
DTWSIGCIFA EILTGKPLFP GKNVVHQLDL MTDLLGTPSM DAISRIRNDK
260 270 280 290 300
ARRYLSSMRR KQPVPFSEKF PNVDPLALKL LQRLLAFDPK DRPTAEEALA
310 320 330 340 350
DPYFKGLAKV EREPSCQPIS KMEFEFERRK VTKDDIKELI FREILEYHPQ
360 370 380 390 400
LLKDYMNGSE NTSFLYPSAV DNFRRQFAIL EENGGKSGAL DRKHVSLPRA
410 420 430 440 450
TTVHSTSIPP NEGLDATSQV TQRIPTARPG RTVGPVLPFE NPGAADPHSA
460 470 480 490 500
RRVVRNPMVP PAAANKSGYS YNLKSDYSDR QHQEELEKDR VQYRPAQHLM
510 520 530 540 550
DAKVAPDTAP DIRSSQYYFT RSAPRTDLTD RAALQGSMLY GIAPFNGIAA
560
VAGGYSKVGA VQYGVSRMY
Length:569
Mass (Da):64,669
Last modified:October 11, 2004 - v1
Checksum:iF2A244BB1D2D8D91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY366480 mRNA Translation: AAR11478.1
AC120986 Genomic DNA No translation available.
AP014961 Genomic DNA No translation available.
UniGeneiOs.18735

Genome annotation databases

EnsemblPlantsiOs05t0566400-01; Os05t0566400-01; Os05g0566400
GrameneiOs05t0566400-01; Os05t0566400-01; Os05g0566400

Similar proteinsi

Entry informationi

Entry nameiMPK7_ORYSJ
AccessioniPrimary (citable) accession number: Q67C40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: October 11, 2004
Last modified: May 23, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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