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Q67BS9 (P19_HARV) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene names
ORF Names:ORF4
OrganismHavel river virus (HaRV)
Taxonomic identifier254711 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the tombusvirus protein p19 family.

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionSuppressor of RNA silencing
Gene Ontology (GO)
   Cellular_componentvirion

Inferred from electronic annotation. Source: InterPro

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 172172RNA silencing suppressor p19
PRO_0000222875

Sequences

Sequence LengthMass (Da)Tools
Q67BS9 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 3CD8A5EE4E6D7387

FASTA17219,082
        10         20         30         40         50         60 
MEGAIQGSDA REQANSERWD GGCGGTITPF KLPDESPGLH EWRLHNSEES EDKDHPLGFK 

        70         80         90        100        110        120 
ESWGFGKVVF KRYLRYDGTE ASLHRALGSW ERGSVNDAAS RFLGLGQVGC TYSIRFRGSC 

       130        140        150        160        170 
LTLSGGSRTL QRLIEMAIRT KRTMLQLTPS EVEGNVSRGR PEGAKAFEKE SE 

« Hide

References

[1]"Isolation of two strains of a new tombusvirus (Havel river virus, HaRV) from surface waters in Germany."
Koenig R., Pfeilstetter E., Kegler H., Lesemann D.E.
Eur. J. Plant Pathol. 110:429-433(2004) [AGRICOLA] [Europe PMC]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
Strain: S.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY370535 Genomic RNA. Translation: AAR28057.1.

3D structure databases

ProteinModelPortalQ67BS9.
SMRQ67BS9. Positions 9-152.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004905. Tombusvirus_p19.
[Graphical view]
PfamPF03220. Tombus_P19. 1 hit.
[Graphical view]
ProDomPD005743. Tombus_P19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF103145. SSF103145. 1 hit.
ProtoNetSearch...

Entry information

Entry nameP19_HARV
AccessionPrimary (citable) accession number: Q67BS9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: October 11, 2004
Last modified: October 16, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families