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Q67AJ0 (Q67AJ0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:HLA-DQB1 EMBL AAQ88044.1
OrganismHomo sapiens (Human) EMBL AAQ88044.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length234 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS014745

Ontologies

Keywords
   Biological processImmunity
   Cellular componentMembrane
MHC II RuleBase RU000321 SAAS SAAS014745
   DomainTransmembrane
Transmembrane helix SAAS SAAS014745
Gene Ontology (GO)
   Biological_processB cell affinity maturation

Inferred from electronic annotation. Source: Ensembl

antigen processing and presentation of exogenous peptide antigen via MHC class II

Inferred from electronic annotation. Source: Ensembl

cellular response to interferon-gamma

Inferred from electronic annotation. Source: Ensembl

positive regulation of T-helper 1 type immune response

Inferred from electronic annotation. Source: Ensembl

positive regulation of alpha-beta T cell activation

Inferred from electronic annotation. Source: Ensembl

positive regulation of antigen processing and presentation

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentGolgi apparatus

Inferred from electronic annotation. Source: Ensembl

MHC class II protein complex

Inferred from electronic annotation. Source: UniProtKB-KW

early endosome

Inferred from electronic annotation. Source: Ensembl

external side of plasma membrane

Inferred from electronic annotation. Source: Ensembl

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

multivesicular body

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionpeptide antigen binding

Inferred from electronic annotation. Source: Ensembl

toxic substance binding

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue2341 EMBL AAQ88044.1

Sequences

Sequence LengthMass (Da)Tools
Q67AJ0 [UniParc].

Last modified October 11, 2004. Version 1.
Checksum: 95A46B3EF03AAE4D

FASTA23426,904
        10         20         30         40         50         60 
MSWKKALRIP GDLRVATVTL MLAMLSSLLA EGRDSPEDFV FQFKGMCYFT NGTERVRLVT 

        70         80         90        100        110        120 
RYIYNREEYA RFDSDVGVYR AVTPQGRPDA EYWNSQKEVL EGTRAELDTV CRHNYEVAFR 

       130        140        150        160        170        180 
GILQRRVEPT VTISPSRTEA LNHHNLLVCS VTDFYPGQIK VRWFRNDQEE TAGVVSTPLI 

       190        200        210        220        230 
RNGDWTFQIL VMLEMTPQRG DVYTCHVEHP SLQSPITVEW RAQSESAQSK MLSG 

« Hide

References

[1]"Comparative haplotype analysis of polymorphism within the DQB1 gene. Continuous sequencing from promoter to exon 4."
Wood J.M., Simons M.J., Ashdown M.L.
Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY375870 Genomic DNA. Translation: AAQ88044.1.
UniGeneHs.409934.
Hs.534322.

3D structure databases

ProteinModelPortalQ67AJ0.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ67AJ0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG012730.

Gene expression databases

ArrayExpressQ67AJ0.
BgeeQ67AJ0.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMSSF54452. SSF54452. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSHLA-DQB1. human.

Entry information

Entry nameQ67AJ0_HUMAN
AccessionPrimary (citable) accession number: Q67AJ0
Entry history
Integrated into UniProtKB/TrEMBL: October 11, 2004
Last sequence update: October 11, 2004
Last modified: March 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.