Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Capsid protein

Gene

V1

Organism
Tomato yellow leaf curl Sardinia virus (isolate Spain-2) (TYLCSV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Encapsidates the viral genome into characteristic twinned ('geminate') particles. Binds the genomic viral ssDNA and shuttles it into and out of the cell nucleus. Plays a role in protection of the genome from degradation, virus acquisition and transmission by insect vectors, infectivity, and systemic movement. The CP of monopartite geminiviruses is absolutely essential for virus movement (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri68 – 8518Sequence analysisAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Viral penetration into host nucleus, Virus entry into host cell

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
Coat protein
Short name:
CP
Gene namesi
ORF Names:V1
OrganismiTomato yellow leaf curl Sardinia virus (isolate Spain-2) (TYLCSV)
Taxonomic identifieri221538 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus
Virus hostiCynanchum acutum [TaxID: 185024]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Solanum nigrum (Black nightshade) [TaxID: 4112]
Proteomesi
  • UP000008266 Componenti: Genome

Subcellular locationi

  • Virion Curated
  • Host nucleus By similarity

  • Note: It is actively transported into the host cell nucleus. It may be exported out of the nucleus through a nuclear export signal for cell-to-cell movement and spread (By similarity).By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, Host nucleus, T=1 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 257257Capsid proteinPRO_0000320109Add
BLAST

Interactioni

Subunit structurei

Homomultimer. Binds to single-stranded and double-stranded viral DNA. Interacts (via nuclear localization signals) with host importin alpha-1a (By similarity).By similarity

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi3 – 2018Bipartite nuclear localization signalSequence analysisAdd
BLAST
Motifi40 – 5415Nuclear localization signalSequence analysisAdd
BLAST
Motifi101 – 12222Nuclear export signalSequence analysisAdd
BLAST
Motifi201 – 24848Bipartite nuclear localization signalSequence analysisAdd
BLAST

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri68 – 8518Sequence analysisAdd
BLAST

Keywords - Domaini

Zinc-finger

Family and domain databases

InterProiIPR000650. Gem_coat_AR1.
IPR000263. GV_A/BR1_coat.
[Graphical view]
PfamiPF00844. Gemini_coat. 1 hit.
[Graphical view]
PRINTSiPR00224. GEMCOATAR1.
PR00223. GEMCOATARBR1.

Sequencei

Sequence statusi: Complete.

Q67617-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKRTGDILM SSPLSKFRRK LNFDSPYTSR AAAPTVQGIK RRSWTYRPMY
60 70 80 90 100
RKPRMYRMYR SPDVPFGCEG PCKVQSYEQR DDVKHTGVVR CVSDVTRGSG
110 120 130 140 150
ITHRVGKRFC IKSIYILGKI WMDENIKKQN HTNQVMFFLV RDRRPYGTSP
160 170 180 190 200
MDFGQVFNMF DNEPSTATVK NDLRDRYQVM RKFHATVVGG PSGMKEQCLL
210 220 230 240 250
KRFFKVNTHV VYNHQEQAKY ENHTENALLL YMACTHASNP VYATLKIRIY

FYDAVTN
Length:257
Mass (Da):30,056
Last modified:November 1, 1996 - v1
Checksum:i209E9B421883A4FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27708 Genomic DNA. Translation: AAA47952.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L27708 Genomic DNA. Translation: AAA47952.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000650. Gem_coat_AR1.
IPR000263. GV_A/BR1_coat.
[Graphical view]
PfamiPF00844. Gemini_coat. 1 hit.
[Graphical view]
PRINTSiPR00224. GEMCOATAR1.
PR00223. GEMCOATARBR1.
ProtoNetiSearch...

Publicationsi

  1. "Characterization of a tomato yellow leaf curl virus isolated from southeast Spain (almeria)."
    Reina J., Cuadrado-Gomez I.M., Jimenez J., Bejarano E.R.
    Submitted (JAN-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCAPSD_TYCS2
AccessioniPrimary (citable) accession number: Q67617
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.