Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear shuttle protein

Gene

DNA B

Organism
Tomato golden mosaic virus-Common
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to the genomic viral ssDNA, shuttles it into and out of the cell nucleus. Begomoviruses use 2 proteins to transport their DNA from cell to cell. The nuclear shuttle protein (NSP) shuttles it between nucleus and cytoplasm and the movement protein (MP) probably transports the DNA-NSP complex to the cell periphery and facilitates movement across the cell wall.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Viral movement proteinUniRule annotation

Keywords - Biological processi

Host-virus interactionUniRule annotation, Transport

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear shuttle proteinUniRule annotation
Short name:
NSPUniRule annotation
Gene namesi
Name:DNA BImported
OrganismiTomato golden mosaic virus-CommonImported
Taxonomic identifieri223340 [NCBI]
Taxonomic lineageiVirusesssDNA virusesGeminiviridaeBegomovirus

Subcellular locationi

  • Host cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Host cytoplasm UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host cell membraneUniRule annotation, Host cytoplasmUniRule annotation, Host membrane, Host nucleusUniRule annotation, Membrane

Interactioni

Subunit structurei

Binds to single-stranded and double-stranded viral DNA. Interacts with the host nuclear shuttle interacting (NSI) protein. This interaction may allow NSP to recruit NSI monomers to the viral genome and thus regulate nuclear export of viral genome by NSP.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the begomovirus nuclear shuttle protein family.UniRule annotation

Family and domain databases

InterProiIPR001530. Gemini_BR1.
IPR000263. GV_A/BR1_coat.
[Graphical view]
PfamiPF00844. Gemini_coat. 1 hit.
[Graphical view]
PRINTSiPR00223. GEMCOATARBR1.
PR00225. GEMCOATBR1.

Sequencei

Sequence statusi: Complete.

Q67600-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSTKYRRGL LANQRRGYPR HSTGKRSHNV SRIDFKRRSS KYVHGNDDSK
60 70 80 90 100
MANQRIHENQ FGPEFVMVHN TAISTFITFP SLGKTEPSRS RSYIKLKRLR
110 120 130 140 150
FKGTVKIERV HVDLSMDGPS PKIEGVFSLV VVVDRQPHLS PTGCLHTFDE
160 170 180 190 200
LFGARIHSHG NLAISSALKD RFYIRHVFKR VISVEKDSTM IDLEGTTSFT
210 220 230 240 250
NRRFNCWSAF KDFDRQACNG VYGNISKNAI LVYYCWMSDI VSKASTFVSF

DLDYVG
Length:256
Mass (Da):29,405
Last modified:November 1, 1996 - v1
Checksum:i2183FB1AE9A13810
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73794 Genomic DNA. Translation: AAA46583.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73794 Genomic DNA. Translation: AAA46583.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR001530. Gemini_BR1.
IPR000263. GV_A/BR1_coat.
[Graphical view]
PfamiPF00844. Gemini_coat. 1 hit.
[Graphical view]
PRINTSiPR00223. GEMCOATARBR1.
PR00225. GEMCOATBR1.
ProtoNetiSearch...

Entry informationi

Entry nameiQ67600_9GEMI
AccessioniPrimary (citable) accession number: Q67600
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.